dc.contributor.author | Ayla, Şule | |
dc.contributor.author | Okur, Mehmet Evren | |
dc.contributor.author | Günal, Mehmet Yalçın | |
dc.contributor.author | Özdemir, Ekrem Musa | |
dc.contributor.author | Çiçek Polat, Derya | |
dc.contributor.author | Yoltaş, Ayşegül | |
dc.contributor.author | Biçeroğlu, Özge | |
dc.contributor.author | Karahüseyinoğlu, Serçin | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:49:36Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T19:49:36Z | |
dc.date.issued | 2019 | en_US |
dc.identifier.citation | Ayla, Ş., Okur, M. E., Günal, M. Y., Özdemir, E. M., Çiçek, P., Yoltaş, A. … Karahüseyinoğlu, S. (2019). Wound healing effects of methanol extract of Laurocerasus officinalis roem. Biotechnic & Histochemistry, 94(3), 180-188. https://dx.doi.org/10.1080/10520295.2018.1539242 | en_US |
dc.identifier.issn | 1052-0295 | |
dc.identifier.issn | 1473-7760 | |
dc.identifier.uri | https://dx.doi.org/10.1080/10520295.2018.1539242 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/1671 | |
dc.description | WOS: 000469009000004 | en_US |
dc.description | PubMed ID: 30409033 | en_US |
dc.description.abstract | Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using an excisional wound model model in mice. We used four groups of eight mice as follows: untreated (control), empty gel, extract +gel (L. officinalis +gel), and Madecassol (R) groups. All treatments were applied topically once daily. The scar area, percentage wound closure and epithelization time were measured. L. officinalis promoted wound healing and increased granulation tissue, epidermal regeneration and angiogenesis. L. officinalis extract, which is known for its antioxidant and antimicrobial activities, may be useful for promoting wound healing. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Antimicrobial | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Extract | en_US |
dc.subject | Laurocerasus Officinalis | en_US |
dc.subject | Mice | en_US |
dc.subject | Wound Healing | en_US |
dc.title | Wound healing effects of methanol extract of Laurocerasus officinalis roem | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Biotechnic & Histochemistry | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) | en_US |
dc.authorid | 0000-0003-2143-5268 | en_US |
dc.authorid | 0000-0001-7702-2441 | en_US |
dc.authorid | 0000-0001-9416-7757 | en_US |
dc.identifier.volume | 94 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 180 | en_US |
dc.identifier.endpage | 188 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1080/10520295.2018.1539242 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q3 | en_US |