Wound healing effects of methanol extract of Laurocerasus officinalis roem
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info:eu-repo/semantics/embargoedAccessTarih
2019Yazar
Ayla, ŞuleOkur, Mehmet Evren
Günal, Mehmet Yalçın
Özdemir, Ekrem Musa
Çiçek Polat, Derya
Yoltaş, Ayşegül
Biçeroğlu, Özge
Karahüseyinoğlu, Serçin
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Ayla, Ş., Okur, M. E., Günal, M. Y., Özdemir, E. M., Çiçek, P., Yoltaş, A. … Karahüseyinoğlu, S. (2019). Wound healing effects of methanol extract of Laurocerasus officinalis roem. Biotechnic & Histochemistry, 94(3), 180-188. https://dx.doi.org/10.1080/10520295.2018.1539242Özet
Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using an excisional wound model model in mice. We used four groups of eight mice as follows: untreated (control), empty gel, extract +gel (L. officinalis +gel), and Madecassol (R) groups. All treatments were applied topically once daily. The scar area, percentage wound closure and epithelization time were measured. L. officinalis promoted wound healing and increased granulation tissue, epidermal regeneration and angiogenesis. L. officinalis extract, which is known for its antioxidant and antimicrobial activities, may be useful for promoting wound healing.
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Biotechnic & HistochemistryCilt
94Sayı
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