Ara
Toplam kayıt 4, listelenen: 1-4
Discussion on "Modeling karst spring hydrograph recession based on head drop at sinkholes" by Guangquan, Li, Nico Goldscheider, Malcom S. Field
(Elsevier Science Bv, 2018)
Groundwater movement model development in karstic aquifers is very difficult due to the complexity of the solution cavities. The authors (Li et al., 2016) have proposed a square law model for expressing the discharge ratio ...
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)
Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)
Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ...