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Toplam kayıt 105, listelenen: 91-100
The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies
(Bentham Science Publishers, 2016)
There are rapidly replicating human data suggesting the therapeutic and neurorestorative role of repetitive transcranial magnetic stimulation (rTMS) in clinical depression. However there are only limited experimental studies ...
B cells and progressive multifocal leukoencephalopathy: Search for the missing link
(Frontiers Media, 2015)
Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease due to JC virus (JCV) replication in the brain. PML classically occurs in patients with severe immunodepression, and cases have recently ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)
G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...
Endobronchial causes
(2013)
Öksürük reseptörleri trakeobronşiyal ağaçta yaygın olarak bulunmaktadır. Endobronşiyal yerleşim gösteren akciğer patolojileri bu nedenle karşımıza sıklıkla öksürükle çıkar. Endobronşial kronik öksürük sebepleri benign ve ...
Surface modified multifunctional and stimuli responsive nanoparticles for drug targeting: Current status and uses
(MDPI, 2016)
Nanocarriers, due to their unique features, are of increased interest among researchers working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules, involving non-toxic biodegradable polymers, ...
Cellular protection and therapeutic potential of tocotrienols
(Bentham Science Publishers Ltd., 2011)
Tocotrienols, components belonging to vitamin E members, are used as potent therapeutics in the treatment of several diseases. Recent studies suggested tocotrienol to have better activity in many situations compared to ...
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)
Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ...
Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview
(Bentham Science Publishers B.V., 2018)
Repetitive transcranial magnetic stimulation (rTMS) is a well known non-invasive brain stimulation procedure which is capable of inducing the expression of the hippocampal BDNF that has been already shown to exert significant ...
The therapeutic role of minocycline in Parkinson's disease
(Bioexcel Publishing LTD, 2019)
Minocycline, a semisynthetic tetracycline-derived antibiotic, has been shown to exert anti-apoptotic, anti-inflammatory, and antioxidant effects. Furthermore, there is rapidly growing evidence suggesting that minocycline ...