Fakülteler by Institution Author "Macit, Çağlar"
Now showing items 1-10 of 10
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Chemical characterization and biological properties of oyster and shiitake mushrooms extracts and their liposomal formulations
In recent years, the production of liposomal formulations using mushroom extracts has gained increasing interest to increase the bioavailability of bioactive compounds in the nutraceutical field. Based on this information, ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
Omurtag Özgen, Pınar Sinem; Biltekin, Sevde Nur; İduğ, Tuğba; Macit, Çağlar; Ayran, İrem; Çelik, Sadiye Ayşe; Kültür, Şükran; Kan, Yüksel; Omurtag, Gülden Zehra (Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Formulation development of Silybum marianum seed extracts and silymarin nanoparticles, and evaluation of hepatoprotective effect
Macit, Meltem; Duman, Gülengül; Cumbul, Alev; Sümer, Engin; Macit, Çağlar (Editions de Sante, 2023)In this study, we formulated silymarin-nanoparticles and assayed their ability to reduce acetaminophen-induced toxicity in vitro and in vivo. After silymarin molecules were encapsulated the loading efficiency and the ... -
Hypertension-related knowledge, attitudes, and behavior among hypertensive patients in a community pharmacy in Sivas, Türkiye: A regional descriptive study
Macit, Çağlar; Taner, Neda (Istanbul Medipol University, 2023)This study scrutinized hypertension-related knowledge, attitudes, and behavior among patients with hypertension. It was performed with 88 hypertensive patients in a community pharmacy in Sivas for one month. Suitably ... -
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
Karakaya Çimen, Fatma Bedia; Macit, Çağlar; Sivas, Güzin Göksun; Tunalı Akbay, Tuğba; Şener, Göksel; Ercan, Feriha (Istanbul University Press, 2023)Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ... -
Nitric oxide mediated effects of nebivolol on erectile function in rats with heart failure
Mercanoğlu, Güldem; Gümrükçü, Gülistan; Macit, Çağlar (IMR Press, 2022)Background and objective: Heart failure (HT) is a common complication of cardiovascular disease, which leads to functional cardiac abnormalities. Beta-blockers are commonly used to reduce mortality in HF patients; however, ... -
Panax ginseng extract ameliorates methotrexate-induced multi-organ damage via the regulation of oxidative stress
Macit, Çağlar; Ede Pazarbaşı, Seren; Yılmaz Karaoğlu, Sümeyye; Tunali Akbay, Tuğba; Karakaya Çimen, Fatma Bedia; Ercan, Feriha; Şener, Göksel (Marmara University, 2023)Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and ... -
Protective effects of momordica charantia (Bitter Melon) against metho-trexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers, 2023)Background: Methotrexate is a cytotoxic chemotherapeutic agent that has severe side ef-fects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage
Macit, Çağlar; Özbeyli, Dilek; Çevik, Özge; Çetin, Melisa; Şener, Göksel; Özkan, Sevil (Bentham Science Publishers Ltd., 2023)Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Steam bath, vibration, and thermal ablation administrations augment the release of tramadol HCl from transdermal patch and enhance the plasma concentration in rats
Macit, Çağlar; Duman, Gülengül; Macit, Meltem (Marmara University, 2023)Recently, transdermal drug delivery has become popular due to their numerous advantages. They offer non-invasive application and eliminate the first-pass metabolism. The skin membrane is sensitive to heat and vibration ...