Kurum Yazarı "Balcı, Nur" Fakülteler İçin Listeleme
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Does smoking influence tryptophan metabolism in periodontal inflammation? A cross-sectional study
Önder, Canan; Akdoğan, Nihan; Kurgan, Şivge; Balcı, Nur; Serdar, Ceyhan Ceran; Ceran Serdar, Ceyhan; Serdar, Muhittin Abdulkadir; Günhan, Meral (John Wiley and Sons Inc, 2023)ObjectivesThe aim of this study was to identify the effects of smoking and periodontal inflammation on tryptophan-kynurenine metabolism as well as the correlation between these findings and clinical periodontal parameters. ... -
Influence of periodontal inflammation on tryptophan-kynurenine metabolism: A cross-sectional study
Kurgan, Şivge; Önder, Canan; Balcı, Nur; Akdoğan, Nihan; Altıngöz, Sema Merve; Serdar, Muhittin Abdulkadir; Günhan, Meral (Springer Heidelberg, 2022)Objectives Kynurenine pathway (KP) is the primary way of degrading tryptophan (TRP) and generates several bioactive metabolites (such as kynurenine (KYN), kynurenic acid (KYNA), 3-hydroxykynurenine (3OHKYN)) to regulate ... -
Oral and gut microbial profiling in periodontitis and parkinson's disease
Yay, Ekin; Yılmaz, Melis; Toygar, Hilal; Balcı, Nur; Rivas, Carla Alvarez; Bolluk Kılıç, Başak; Zırh, Ali; Paster, Bruce J.; Kantarcı, Alpdoğan (Taylor & Francis Ltd, 2024)ObjectivesWe tested the hypothesis that Parkinson's disease (PA) alters the periodontitis-associated oral microbiome.MethodPatients with periodontitis with Parkinson's disease (PA+P) and without PA (P) and systemically and ... -
Oxidative stress and foxo-1 relationship in stage iii periodontitis
Gürbüz, Elif Selin; Güney, Zeliha; Kurgan, Şivge; Balcı, Nur; Serdar, Muhittin Abdulkadir; Günhan, Meral (2024)Objectives: 8-Hydroxideoxyguanosine (8-OHdG) is a marker of oxidative stress, and Forkhead Box-O1 (FOXO1) is a transcription factor and signaling integrator in cell and tissue homeostasis. This study aims to determine FOXO1 ... -
Parkinson's disease is positively associated with periodontal inflammation
Yılmaz, Melis; Yay, Ekin; Balcı, Nur; Toygar, Hilal; Bolluk Kılıç, Başak; Zırh, Ali; Rivas, Carla Alvarez; Kantarcı, Alpdoğan (Wiley, 2023)BackgroundParkinson's disease (PA) affects 1% of the global population above 60 years. PA pathogenesis involves severe neuroinflammation that impacts systemic and local inflammatory changes. We tested the hypothesis that ... -
Parkinson’s disease alters the composition of subgingival microbiome
Yay, Ekin; Yılmaz, Melis; Toygar, Hilal; Balcı, Nur; Alvarez Rivas, Carla; Bolluk Kılıç, Başak; Zırh, Ali; Paster, Bruce; Kantarcı, Alpdoğan (Taylor and Francis Ltd., 2023)Aim: The current study aimed to test the hypothesis that Parkinson’s disease exacerbates periodontitis by altering its microbiome. Materials and Methods: Clinical periodontal parameters were recorded. Subgingival samples ... -
Salivary irisin level is higher and related with interleukin-6 in generalized periodontitis
Türkmen, Emrah; Uzun, Erdem Veli; Bozaba, Fuat; Balcı, Nur; Toygar, Hilal (Springer Science and Business Media Deutschland GmbH, 2023)Objectives: Irisin plays an important role in energy homeostasis, inflammation, glucose, and lipid metabolism, and it is shown to have relations with many inflammatory diseases. The aim of the study was to determine saliva ... -
Serum, saliva, and gingival tissue human beta-defensin levels in relation to retinoic acid use
Atalay, Nur; Balcı, Nur; Uslu Toygar, Hilal; Yardımcı, Gürkan; Gürsoy, Ulvi Kahraman (Wiley, 2023)BackgroundRetinoic acid is an active derivative of vitamin A and regulates the differentiation, proliferation, and antimicrobial peptide expression profiles of human cells. The aim of the present study was to analyze the ... -
Sirtuin6 and Lipoxin A4 levels are decreased in severe periodontitis
Çekici, Ali; Şahinkaya, Selin; Dönmez, Mehmet Fatih; Türkmen, Emrah; Balcı, Nur; Toygar, Hilal (Springer, 2023)Objective: Sirtuin6 plays an important role in the regulation of inflammation, homeostasis, and apoptosis, and it has anti-inflammatory effects on several diseases. Lipoxin A4 is a pro-resolving lipid mediator of inflammation ...