Kurum Yazarı "Bülbül, Muhammet Volkan" Fakülteler İçin Listeleme
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Antiproliferative and apoptotic effects of onobrychis albiflora extract on HCT-116 cells
Bülbül, Muhammet Volkan; Özbek, Hanefi; Bahadır Acıkara, Özlem; Özbilgin, Serkan; Ergene Öz, Burçin; Kurtul, Ekin; Keskin, İlknur (Ondokuz Mayıs University, 2018)In this study, the cytotoxic effects of the extracts of methanol: water (80:20) prepared from the above-ground parts of the varieties of Onobrychis albiflora Hub.-Mor., Onobrychis argyrea Boiss. subsp. argyrea, Onobrychis ... -
Benzotriazole-oxadiazole hybrid compounds: Synthesis, anticancer activity, molecular docking and ADME profiling studies
Mermer, Arif; Bülbül, Muhammet Volkan; Kalender, Semiha Mervenur; Keskin, İlknur; Tüzün, Burak; Eyüpoğlu, Ozan Emre (Elsevier B.V., 2022)Herein the designed novel benzotriazole-oxadiazole hybrid compounds were synthesized using both conventional method and ultrasound sonication (US) as an environmentally friendly method. It was observed that the US method ... -
In 2D and 3D cell culture models, effects of endothelial cells on E-cadherin / β-catenin expression levels and spheroid sizes in ishikawa cells
Kalender, Mervenur; Bülbül, Muhammet Volkan; Kolbaşı, Bircan; Keskin, İlknur (Asian Pacific Organization for Cancer Prevention, 2022)Increasing evidence shows that three dimensional cell culture models better reflect the in vivo tumor microenvironment than two dimensional cell culture models. Co-culture models are ideal cell culture models for understanding ...