Kurum Yazarı "Çakıcı, Çağrı" Fakülteler İçin Listeleme
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Can lactate dehydrogenase inhibition be increased efficiency of 1,25(OH)2 D3 vitamin in prostate cancer animal model?
Çakıcı, Çağrı; Daylan, Benay; Ayla, Şule; Yiğit, Pakize; Yavuz Dokgöz, Elif; Yigitbaşı, Türkan (NLM (Medline), 2022)The Warburg effect explains that the cancer cell's metabolism is programmed based on anaerobic glycolysis to support the proliferation and anabolic growth of cancer cells. LDH-A is the form of LDH found in cancer cells, ... -
Could the increase in oxidative stress be the reason for the increased polyamine levels in diabetic obese and non-diabetic obese patients?
Göktürk, Nurcan; Şahin, Hicret; Bayramoğlu, Feyza; Çakıcı, Çağrı; Büyükuslu, Nihal; Yiğit, Pakize; Yiğitbaşı, Türkan (İstanbul Medipol University, 2022)Putresin, spermine, and spermidine are important polyamines found in all living organisms. In this study, as a first in the literature, we aimed to investigate polyamines levels and their relationship with oxidative stress ... -
Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
Aydeğer, Asel; Ayşit, Neşe; Baydaş, Gülsena; Çakıcı, Çağrı; Erim, Ümit Can; Arpa, Muhammet Davut; Özçiçek, İlyas (Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto’s thyroiditis
Tunç, Sümeyye; Altuntaş, Şükriye Leyla; Atmaca, Murat; Çakıcı, Çağrı; Yiğitbaşı, Türkan; Liou, Yeong Cheng; Chang, Wei An (2024)This study aimed to examine the effects of low-level laser therapy (LLLT) combined with levothyroxine replacement therapy on thyroid function, oxidative stress (OS), and quality of life in patients with Hashimoto’s thyroiditis ... -
The effects of gold nanoparticles with different surface coatings and sizes on biochemical parameters in mice
Özçiçek, İlyas; Çakıcı, Çağrı; Ayşit, Neşe; Erim, Ümit Can (Prusa Medical Publishing, 2023)Objectives: Gold nanoparticles are very popular metallic nanomaterials and they have a wide spectrum of biomedical applications. This study was aimed to the production of stable and monodisperse polyethyleneimine (PEI) and ... -
Effects of hardaliye, a fermented grape drink, on oxidative stress, lipid profile, and blood pressure in young soccer players: a randomized controlled trial
Atan, Ramazan Mert; Ersoy, Gülgün; Çakıcı, Çağrı (2024)Objective: Hardaliye, a traditional fermented grape juice, can prevent imbalances in the antioxidant defense systems of soccer players. Hardaliye is mainly produced through the fermentation of grapes, sour cherry leaves, ... -
Large-scale proteomic analysis of patients with type 2 diabetes mellitus and atherosclerosis using a label-free LC-MS/MS approach
Sürmen, Mustafa Gani; Alkan Bozkaya, Tijen; Ateş, Mehmet Şanser; Sürmen, Saime; Çakıcı, Çağrı; Pençe, Sadrettin; Emekli, Nesrin (Istanbul University, 2023)Objective: Type 2 diabetes mellitus (T2D) is a metabolic disease whose molecular events have not yet been fully clarified. However, next-generation powerful molecular approaches such as mass spectrometry (MS)-based proteomics ... -
LDH-A inhibitor as a remedy to potentiate the anticancer effect of docetaxel in prostate cancer
Çakıcı, Çağrı; Daylan, Benay; Ünlüer, Rüveyde Safiye; Emekli Alturfan, Ebru; Ayla, Şule; Eren Gözel, Hilal; Yiğit, Pakize; Yavuz Dokgöz, Elif; Yiğitbaşı, Türkan (Ivyspring International Publisher, 2024)Increased LDH-A activity promotes tumor growth, migration, invasion, and metastasis. This study aimed to investigate the effects of the combination of LDH-A inhibitor and Docetaxel on apoptosis and epithelial-mesenchymal ... -
The relationship between zonulin and metabolic syndrome in renal transplant patients
Canbaloğlu Erkan, Gülbanu; Şumnu, Abdullah; Ertuğrul, Gökhan; Ülfer, Gözde; Çakıcı, Çağrı; Aydın, Hüseyin Çağatay; Ünal, Aydın (Verlag Klinisches Labor GmbH, 2023)Background: Levels of zonulin, a surrogate marker of intestinal permeability, are elevated in various disorders including insulin resistance, obesity, celiac disease, and inflammatory bowel disease. We aimed to elucidate ... -
Tissue factor and vascular endothelial growth factor in detecting thromboembolic complications in diabetic atherosclerotic patients
Alkan Bozkaya, Tijen; Ateş, Şanser; Üstündağ, Ünsal Veli; Çakıcı, Çağrı; Keskin, İlknur; Yiğit, Pakize; Yiğitbaşı, Ahmet; Emekli, Nesrin (Sage Publications Ltd, 2023)BackgroundAtherosclerosis, which is one of the leading causes of death all over the world, can create major or minor thromboembolic complications with the exponentially increasing diabetic status. Despite all the studies, ...