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dc.contributor.authorYüce, Meral
dc.contributor.authorKurt, Hasan
dc.contributor.authorHussain, Babar
dc.contributor.authorBudak, Hikmet
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:38:13Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:38:13Z
dc.date.issued2018en_US
dc.identifier.citationYüce, M., Kurt, H., Hussain, B. ve Budak, H. (2018). Systematic evolution of ligands by exponential enrichment for aptamer selection. Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation içinde (211-243. ss.). Elsevier. https://dx.doi.org/10.1016/B978-0-323-50878-0.00008-2en_US
dc.identifier.isbn9780323508797
dc.identifier.isbn9780323508780en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1556
dc.identifier.urihttps://dx.doi.org/10.1016/B978-0-323-50878-0.00008-2
dc.description.abstractDiscovery of aptamers and developments in the field of nanotechnology has made a significant contribution to the field of biosensing. Nanomaterials with various physical, optic, and electronic properties have been functionalized with aptamers, which are the synthetic counterparts of the conventional antibodies, to be used as more stable and cost-effective affinity probes for the detection of target molecules ranging from small ions, disease biomarkers, cell surfaces, microorganisms, and hazardous materials to food-borne allergens and pathogens. In this chapter, we described the fundamental methodology for in vitro aptamer selection, known as systematic evolution of ligands by exponential enrichment, with recent examples from the literature. We also provide the audience with graphical abstracts and illustrations for a better understanding of the aptamer selection concept.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectAptameren_US
dc.subjectBiosensingen_US
dc.subjectNext-Generation Sequencingen_US
dc.subjectOligonucleotideen_US
dc.subjectPost-SELEX Modificationen_US
dc.subjectSELEXen_US
dc.titleSystematic evolution of ligands by exponential enrichment for aptamer selectionen_US
dc.typebookParten_US
dc.relation.ispartofBiomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translationen_US
dc.departmentİstanbul Medipol Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.authorid0000-0002-1677-644Xen_US
dc.identifier.startpage211en_US
dc.identifier.endpage243en_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.identifier.doi10.1016/B978-0-323-50878-0.00008-2en_US


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