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dc.contributor.authorBener, Abdülbari
dc.contributor.authorEliaçık, Mustafa
dc.contributor.authorCıncık, Hakan
dc.contributor.authorÖztürk, Mustafa
dc.contributor.authorDeFronzo, Ralph Albarado
dc.contributor.authorAbdul-Ghani, Muhammad A.
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:37:14Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:37:14Z
dc.date.issued2018en_US
dc.identifier.citationBener, A., Eliaçık, M., Cıncık, H., Öztürk, M., DeFronzo, R. ve Abdul-Ghani, M. (2018). The impact of vitamin D deficiency on retinopathy and hearing loss among type 2 diabetic patients. BioMed Research International, 2018. https://dx.doi.org/10.1155/2018/2714590en_US
dc.identifier.issn2314-6133
dc.identifier.issn2314-6141
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1361
dc.identifier.urihttps://dx.doi.org/10.1155/2018/2714590
dc.description.abstractAim. The current study was aiming to investigate the relation between vitamin D, retinopathy, and hearing loss among type 2 diabetes mellitus (T2DM) patients. Methods. Cross-sectional study carried on 638 subjects aged between 20 and 60 years who visited the Endocrinology, Ophthalmology, and ENT Outpatient Clinics of the Medipol Hospital during the period from March 2016 to May 2017. Two audiometers Grason Stadler GSI 61 and Interacoustics AC40 Clinical audiometer were used to evaluate the hearing loss. Risk factors for diabetic retinopathy were evaluated, including age, sex, diabetes duration, glycated hemoglobin (HbA1c), hypertension, and lipid profiles. Results. The mean age (± SD, in years) for retinopathy with hearing loss versus normal subjects was 47.7 ±10.2 versus 48.5±9.1. The associated risk factors were significantly higher in T2DM with hearing loss, hypertension (32.6% versus 15.7%), tinnitus (40.0% versus 18.0%), vertigo (59.7% versus 26.8%), and headache (54.9% versus 45.3%), than in normal hearing diabetes. There were statistically significant differences between hearing impairment versus normal hearing for vitamin D [19.40±9.71 ng/ml versus 22.67±9.28 ng/ml; p<0.001], calcium, magnesium, phosphorous, cholesterol, HDL-C, LDL-C, albumin, systolic blood pressure [131.70±9.25 Hg versus 127.73±11.98 Hg], diastolic blood pressure [82.20±8.60 mm Hg versus 79.80±8.20 mm Hg], and microalbuminuria. Multivariate logistic regression analysis revealed that variables such as vertigo, duration of DM, mobile/I pad phone, vitamin D deficiency, sleeping disturbance, headache, frequently TV watching, tinnitus, cigarette smokers, and hypertension were considered at higher risk as a predictors of retinopathy with hearing loss among diabetic patients. Conclusion. Vitamin D deficiency is considered as a risk factor for diabetic retinopathy and hearing loss among diabetic patients. Meanwhile, hyperglycemia could be considered as a modifiable risk factor for diabetic retinopathy; tight glycemic control may be the most effective and important therapy for improving quality of life and substantially reducing the incidence of retinopathy and in T2DM patients.en_US
dc.description.sponsorshipIstanbul Medipol University, International School of Medicine; Istanbul Medipol Universityen_US
dc.language.isoengen_US
dc.publisherHindawi Limiteden_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVitamin Den_US
dc.subjectVitamin D Deficiencyen_US
dc.subjectVitamin D3en_US
dc.subjectAlbuminen_US
dc.subjectBilirubinen_US
dc.subjectCalciumen_US
dc.subjectCholesterolen_US
dc.titleThe impact of vitamin D deficiency on retinopathy and hearing loss among type 2 diabetic patientsen_US
dc.typearticleen_US
dc.relation.journalBioMed Research Internationalen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0002-7902-5803en_US
dc.authorid0000-0002-2563-2149en_US
dc.authorid0000-0002-6221-7788en_US
dc.identifier.volume2018en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1155/2018/2714590en_US


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