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dc.contributor.authorİlgenli, Tevfik Fikret
dc.contributor.authorTokatlı, Alptuǧ
dc.contributor.authorAkpınar, Onur
dc.contributor.authorKılıçaslan, Fethi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:47Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:47Z
dc.date.issued2015en_US
dc.identifier.citationİlgenli, T. F., Tokatlı, A., Akpınar, O. ve Kılıçaslan, F. (2015). The effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. Advances in Clinical and Experimental Medicine, 24(6), 973-978. https://dx.doi.org/10.17219/acem/28114en_US
dc.identifier.issn1899-5276
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1254
dc.identifier.urihttps://dx.doi.org/10.17219/acem/28114
dc.description.abstractBackground. Cigarette smoking increases the risk of sudden cardiac death. Smoking may predispose individuals to ventricular fibrillation and sudden cardiac death by altering ventricular repolarization and stimulating sympathetic nervous system activity. Objectives. The aim of the study was to investigate the instantaneous effects of smoking on ventricular repolarization. Material and Methods. The study included 47 healthy subjects; 24 long-term heavy smokers (10 women, mean age: 40 ± 5 years) constituted the study group, and 23 non-smokers (10 women, mean age: 42 ± 10 years) constituted the control group. ECGs were performed on all the subjects. The Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio were measured and compared between the groups. Results. There were no significant differences between smokers and nonsmokers in the basic clinical and echocardiographic variables (p > 0.05). The QT interval and QTc interval were similar in both groups. The Tp-e interval (p = 0.02) and Tpe/QT ratio (p = 0.001) were higher in the heavy smokers than in the non-smokers. The Tpe/QTc ratio (p = 0.001) was also higher in the smokers. Other ECG parameters were similar between the smokers and nonsmokers. Conclusions. The results show that chronic cigarette smoking is associated with a prolonged Tp-e interval, increased Tp-e/QT ratio and Tp-e/QTc ratio. These observations may indicate that there may be a relationship between smoking and altered ventricular repolarization. Abnormal ventricular repolarization values on an ECG may explain the increased cardiovascular event risk in long-term heavy cigarette smokers.en_US
dc.language.isoengen_US
dc.publisherWroclaw University of Medicineen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmokingen_US
dc.subjectTp-e Intervalen_US
dc.subjectTp-e/QT Ratioen_US
dc.subjectTp-e/QTc Ratioen_US
dc.titleThe effects of cigarette smoking on the Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratioen_US
dc.typearticleen_US
dc.relation.journalAdvances in Clinical and Experimental Medicineen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.identifier.volume24en_US
dc.identifier.issue6en_US
dc.identifier.startpage973en_US
dc.identifier.endpage978en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.17219/acem/28114en_US


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