Synthesis and antifungal activities of some aryl naphthofuran ketoximes
MetadataShow full item record
CitationKaraburun, A. Ç., Gündoğdu Karaburun, N., Uçucu, Ü. ve Demirayak, Ş. (2011). Synthesis and antifungal activities of some aryl naphthofuran ketoximes. Letters in Drug Design and Discovery, 8(8), 758-762. https://doi.org/10.2174/157018011796576097
In this study, some aryl naphtho[2, 1-b]furan-2-yl ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, 1H-NMR and MASS spectroscopic data and elemental analyses results. Antifungal activities of the compounds were tested against Candida albicans (two strains), Candida glabrata, Candida tropicalis and Candida parapsilosis using a microbroth dilution technique. The results showed that the compounds displayed minimum inhibitory concentrations, 7.8-625 µg/mL.