Standardized uptake values highly correlate with tumor size and Fuhrman grade in patients with clear cell renal cell carcinoma
AuthorPolat, Emre Can
Horsanalı, Mustafa Ozan
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CitationPolat, E. C., Ötünçtemur, A., Özbek, E., Beşiroğlu, H., Dursun, M., Özer, K. ... Horsanalı, M. O. (2014). Standardized uptake values highly correlate with tumor size and Fuhrman grade in patients with clear cell renal cell carcinoma. Asian Pacific Journal of Cancer Prevention, 15(18), 7821-7824. https://dx.doi.org/10.7314/APJCP.2014.15.18.7821
Background: We investigated the correlation between standardized uptake value (SUVmax), tumor size and Fuhrman grade in patients with renal cell carcinoma (RC). Materials and Methods: We retrospectively analyzed the data of 54 patients with clear cell renal cell carcinoma histopathologically diagnosed who underwent fluorine-18 fluoro-2 deoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) between January 2005 and March 2014. Results: Avarage tumor sizes were 5.64±1.85, 6.85±2.24 and 7.98±2.45 in low, medium and high SUVmax groups, respectively. The Spearman's correlation coefficient between the tumor size and SUVmax was 0.385 (p=0.004) and between the Fuhrman grade and SUVmax was 0.578 (p<0.001). Conclusions: SUVmax appears highly correlated with tumor size and Fuhrman grade in patients with histopathologically confirmed clear cell RC. Multicenter studies are needed to provide larger series for more accurate results.