dc.contributor.author | Keşke, Murat | |
dc.contributor.author | Canda, Abdullah Erdem | |
dc.contributor.author | Karadağ, Mert Ali | |
dc.contributor.author | Çiftçi, Halil | |
dc.contributor.author | Erturhan, Sakip | |
dc.contributor.author | Kaçtan, Çağrı | |
dc.contributor.author | Soytaş, Mustafa | |
dc.contributor.author | Özkaya, Fatih | |
dc.contributor.author | Özbey, İsa | |
dc.contributor.author | Ördek, Eser | |
dc.contributor.author | Atmaca, Ali Fuat | |
dc.contributor.author | Yıldırım, Asıf | |
dc.contributor.author | Şahin, Selçuk | |
dc.contributor.author | Çolakoğlu, Yunus | |
dc.contributor.author | del Pilar Laguna Pes, Maria | |
dc.date.accessioned | 2023-09-18T09:12:36Z | |
dc.date.available | 2023-09-18T09:12:36Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Keşke, M., Canda, A. E., Karadağ, M. A., Çiftçi, H., Erturhan, S., Kaçtan, Ç. ... del Pilar Laguna Pes, M. (2023). A retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian uro-oncology association multicenter study. Urologia Internationalis. https://dx.doi.org/10.1159/000531645 | en_US |
dc.identifier.issn | 0042-1138 | |
dc.identifier.issn | 1423-0399 | |
dc.identifier.uri | https://dx.doi.org/10.1159/000531645 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/11447 | |
dc.description.abstract | Introduction: Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. Methods: This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible with testicular dysgenesis syndrome. Histology was categorized per size and risk groups. Results: TSS was performed in 83 patients (86 tumors) of them, 27 in the high-risk group. Fifty-nine patients had a non-tumoral contralateral testis present. Sixty masses and 26 masses were benign and TGCTs, respectively. No statistical differences were observed in mean age (30.9 ± 10.32 years), pathological tumor size (14.67 ± 6.7 mm) between risk groups or between benign and malignant tumors (p = 0.608). When categorized per risk groups, 22 (73.3%) and 4 (7.1%) of the TSS specimens were malignant in the high- and low-risk patient groups, respectively. Univariate analysis showed that the only independent variable significantly related to malignant outcome was previous history of TGCT. During a mean follow-up of 25.5 ± 22.7 months, no patient developed systemic disease. Local recurrence was detected in 5 patients and received radical orchiectomy. Postoperative testosterone levels remained normal in 88% of those patients with normal preoperative level. No erectile dysfunction was reported in patients with benign lesions. Conclusion: TSS is a safe and feasible approach with adequate cancer control, and preservation of sexual function is possible in 2/3 of patients harboring malignancy. Incidence of TGCT varies extremely between patients at high and low risk for TGCT requiring a careful consideration and counseling. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Karger | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Germ Cell Testicular Cancer | en_US |
dc.subject | Partial Orchiectomy | en_US |
dc.subject | Testicular Tumor | en_US |
dc.subject | Testis-Sparing Surgery | en_US |
dc.title | A retrospective analysis of 83 patients with testicular mass who underwent testis-sparing surgery: The Eurasian uro-oncology association multicenter study | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Urologia Internationalis | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-3474-3510 | en_US |
dc.authorid | 0000-0003-0906-4417 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1159/000531645 | en_US |
dc.institutionauthor | Kaçtan, Çağrı | |
dc.institutionauthor | Soytaş, Mustafa | |
dc.institutionauthor | del Pilar Laguna Pes, Maria | |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.wos | 001102611400003 | en_US |
dc.identifier.scopus | 2-s2.0-85170556538 | en_US |
dc.identifier.pmid | 37591208 | en_US |
dc.identifier.scopusquality | Q2 | en_US |