Browsing Tez Koleksiyonu by Type "masterThesis"
Now showing items 21-40 of 63
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Development of EPPT1 targeted biocompatible drug delivery system and investigation of its anticancer activity
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2020)Recently, the superior properties of graphene to other biomaterials have made graphene an indispensable and unique material for anticancer drug delivery research, gene and peptide transport. On the other hand, the undeniable ... -
Development of a histotripsy agent using host-guest interaction
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2017)Histotripsy is a mechanical cell ablation technique, which works on the mechanism of acoustic cavitation using microsecond-long, high-frequency ultrasound (US) pulses that can generate a bubble cloud (cavitation) using the ... -
Development of a wireless multichannel neural data transmission system
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2017)Implantable microelectrode arrays enable multichannel electrophysiological recordings from the mammalian brain during behavioral experiments. Wireless data transmission systems combined with the microelectrode arrays and ... -
Development of anti-cancer nanoformulations by incorporation of water-insoluble natural bioactive agents into lipid-based drug delivery systems
(İstanbul Medipol Üniversitesi, Fen Bilimleri Enstitüsü, 2022)Broccoli is a well-known and highly consumed vegetable around the world, it falls into the cruciferous category, which is proven to be effective against breast, skin, and prostate cancers. This anti-cancer property stems ... -
Digital filter and analog LDO design for ADPLL in 180 nm CMOS technology
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2021)PLL is a control system built by elements that synchronize frequency and phase of a stable reference signal with an oscillator output signal. In 21st century, PLL is widely and essentially used in one's daily life in ... -
Directivity enhancement of 60 GHz microstrip patch antennas using dielectric fabry-perot resonantors
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2019)The 60 GHz frequency band offers many opportunities for innovations in the wireless network technology, unlike other bands. Since the wavelength in the 60 GHz band is millimetric, this band can suitably represent the ... -
Dynamic range enhancement in light field imaging systems
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2019)High dynamic range imaging has been an active research area in computational photography over the last two decades. The main reason is that the dynamic range of a traditional camera is typically less than the dynamic range ... -
Emulation techniques for small scale fading aspects of wireless channels by using reverberation chamber
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2018)Reverberation chambers (RVCs) are used to provide an effective and reliable testbed for emulating wireless channel effects in the laboratory environment. Various techniques that enrich the capabilities of the RVC in channel ... -
Eritrosit envanter yönetiminde derin pekiştirmeli öğrenme
(İstanbul Medipol Üniversitesi, Fen Bilimleri Enstitüsü, 2022)Dünya çapında en yaygın olarak uygulanan tedavi yöntemlerinden birisi kan transfüzyonudur. Sağlığın korunmasında ve hayatların kurtarılmasında kan ürünlerinin doğru bir şekilde temini çok önemli bir rol oynamaktadır. Her ... -
Evaluation of dopamine signaling in the rat ventromedial striatum for varying reward proximity
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2020)Dopaminergic neurons play an important role in reward-mediated learning and motor control. In this work, we studied the transient changes in dopamine concentration in the ventromedial striatum (VMS) or nucleus accumbens ... -
Extending light field camera capabilities
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2017)A traditional camera captures an image by projecting a scene on a two-dimensional image sensor plane regardless of the direction light rays coming onto the sensor. A light field camera, in contrast, records light rays in ... -
Extracting sub-exposure images from a single capture through fourier-based optical modulation
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2017)Through pixel-wise optical coding of images during exposure time, it is possible to extract sub-exposure images from a single capture. Such a capability can be used for different purposes, including high-speed imaging, ... -
Finite element analysis of cervical spine & finite element modeling of knee joint
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2017)Finite Element (FE) analysis allows predicting the behavior of real life systems in controlled environment. In the recent decades, FE modeling has gained significant attention of the medical industry as well. There is no ... -
Fizik tedavi ve rehabilitasyon ünitesinin simülasyon yöntemi ile değerlendirilmesi
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2021)Sağlık sektörü içerisinde yer alan kurumların ortak amaçlarından birisi de sağlık hizmeti sunumunun kesintisiz, kaliteli ve verimli bir şekilde gerçekleştirmektir. Bu doğrultuda istenilen sağlık hizmetini sunmak için hasta ... -
FM band channel measurements and modelling
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2018)As the demand for higher data rates increases every day, the need for new frequency bands becomes more and more prominent. The FM band between 88 and 108 MHz is one of the bands that are not fully utilized. This band for ... -
Hasta güvenliği kültürü boyutlarının çok kriterli karar verme yöntemi ile değerlendirilmesi
(İstanbul Medipol Üniversitesi, Fen Bilimleri Enstitüsü, 2022)Sağlık hizmeti sunumunda tıbbi hatalardan kaynaklanan ölümler hasta güvenliği kavramını beraberinde getirmiştir. Hasta güvenliğini sağlık hizmetinin hastaya zarar vermeden sağlanması olarak tanımlamak mümkündür. Hasta ... -
A high-resolution time to digital converter design for all digital phase-locked loops
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2021)Phase-locked loops are one of the most significant modules that are used not only for communication circuits but also in other fields like biomedical and computer sciences. There are many types of PLLs such as Analog, ... -
In silico phosphorylation-independent activation of arrestin-3 protein by means of small molecules
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2019)G protein-coupled receptors (GPCRs) are responsible for communication of the cell with its surroundings. Upon ligand binding, a set of conformational changes occurs at the GPCR, which triggers activation and dissociation ... -
An integrative gene-expression analysis of axolotl limb wound healing and regeneration
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2019)Axolotl is a member of the urodele amphibians that exhibits extraordinary regenerative and scarless wound healing capabilities, fully restoring a lost limb as well as efficiently healing a damaged one. Axolotl has recently ... -
Investigation of the candidate tumor suppressor gene CTCF using multi-omics data mining
(İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2021)CCCTC binding factor (CTCF) is a vertebrate, 11-zinc-finger protein. This ubiquitously expressed multifunctional transcription factor can bind to a myriad of target sites in the genome. It is involved, among others, in ...