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Synthesis and antimycobacterial activity evaluation of isatin-derived 3- [(4-aryl-2-thiazolyl])hydrazone]-1H-indol-2,3-diones

dc.contributor.authorYurttaş, Leyla
dc.contributor.authorErtaş, Merve
dc.contributor.authorCankılıç Yılmaz, Meral
dc.contributor.authorDemirayak, Şeref
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:14Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:14Z
dc.date.issued2017en_US
dc.identifier.citationYurttaş, L., Ertaş, M., Cankılıç Yılmaz, M. ve Demirayak, Ş. (2017). Synthesis and antimycobacterial activity evaluation of isatin-derived 3- [(4-aryl-2-thiazolyl])hydrazone]-1H-indol-2,3-diones. Acta Pharmaceutica Sciencia, 55(1), 51-58. https://dx.doi.org/10.23893/1307-2080.APS.0554en_US
dc.identifier.issn1307-2080
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1104
dc.identifier.urihttps://dx.doi.org/10.23893/1307-2080.APS.0554
dc.description.abstractA series of 3-[(4-aryl-2-thiazolyl)hydrazone]-1H-indol-2,3-dione derivatives (2a-f) were designed and synthesized using isatin as starting material. The obtained thiazole compounds were screened to investigate their antituberculosis activity against Mycobacterum tuberculosis H37RV (ATCC 27294). Among them, two compounds 2c and 2d were displayed antitubercular potential two-fold greater than standard drugs.en_US
dc.language.isoengen_US
dc.publisherUniversity of Istanbulen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimycobacterial Activityen_US
dc.subjectIsatinen_US
dc.subjectIndoleen_US
dc.subjectThiazoleen_US
dc.subjectAntimycobacterial Activityen_US
dc.titleSynthesis and antimycobacterial activity evaluation of isatin-derived 3- [(4-aryl-2-thiazolyl])hydrazone]-1H-indol-2,3-dionesen_US
dc.typearticleen_US
dc.relation.ispartofActa Pharmaceutica Scienciaen_US
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalıen_US
dc.authorid0000-0002-2289-7950en_US
dc.authorid0000-0002-0841-1299en_US
dc.identifier.volume55en_US
dc.identifier.issue1en_US
dc.identifier.startpage51en_US
dc.identifier.endpage58en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.23893/1307-2080.APS.0554en_US
dc.identifier.scopusqualityQ4en_US


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