dc.contributor.author | Babiloni, Claudio | |
dc.contributor.author | Noce, Giuseppe | |
dc.contributor.author | Ferri, Raffaele | |
dc.contributor.author | Lizio, Roberta | |
dc.contributor.author | Lopez, Susanna | |
dc.contributor.author | Lorenzo, Ivan | |
dc.contributor.author | Tucci, Federico | |
dc.contributor.author | Soricelli, Andrea | |
dc.contributor.author | Zurrón, Montserrat | |
dc.contributor.author | Díaz, Fernando | |
dc.contributor.author | Nobili, Flavio | |
dc.contributor.author | Arnaldi, Dario | |
dc.contributor.author | Famà, Francesco | |
dc.contributor.author | Buttinelli, Carla | |
dc.contributor.author | Giubilei, Franco | |
dc.contributor.author | Cipollini, Virginia | |
dc.contributor.author | Marizzoni, Moira | |
dc.contributor.author | Güntekin, Bahar | |
dc.contributor.author | Yıldırım, Ebru | |
dc.contributor.author | Hanoğlu, Lütfü | |
dc.contributor.author | Yener, Görsev | |
dc.contributor.author | Hünerli Gündüz, Duygu | |
dc.contributor.author | Onorati, Paolo | |
dc.contributor.author | Stocchi, Fabrizio | |
dc.contributor.author | Vacca, Laura | |
dc.contributor.author | Maestú, Fernando | |
dc.contributor.author | Frisoni, Giovanni B. | |
dc.contributor.author | del Percio, Claudio | |
dc.date.accessioned | 2023-01-11T09:13:53Z | |
dc.date.available | 2023-01-11T09:13:53Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Babiloni, C., Noce, G., Ferri, R., Lizio, R., Lopez, S., Lorenzo, I. ... del Percio, C. (2022). Resting state alpha electroencephalographic rhythms are affected by sex in cognitively unimpaired seniors and patients with alzheimer's disease and amnesic mild cognitive impairment: A retrospective and exploratory study. Cerebral Cortex, 32(10), 2197-2215. https://dx.doi.org/10.1093/cercor/bhab348 | en_US |
dc.identifier.issn | 1047-3211 | |
dc.identifier.issn | 1460-2199 | |
dc.identifier.uri | https://dx.doi.org/10.1093/cercor/bhab348 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/10284 | |
dc.description.abstract | In the present retrospective and exploratory study, we tested the hypothesis that sex may affect cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms recorded in normal elderly (Nold) seniors and patients with Alzheimer's disease and mild cognitive impairment (ADMCI). Datasets in 69 ADMCI and 57 Nold individuals were taken from an international archive. The rsEEG rhythms were investigated at individual delta, theta, and alpha frequency bands and fixed beta (14-30 Hz) and gamma (30-40 Hz) bands. Each group was stratified into matched females and males. The sex factor affected the magnitude of rsEEG source activities in the Nold seniors. Compared with the males, the females were characterized by greater alpha source activities in all cortical regions. Similarly, the parietal, temporal, and occipital alpha source activities were greater in the ADMCI-females than the males. Notably, the present sex effects did not depend on core genetic (APOE4), neuropathological (A beta 42/phospho-tau ratio in the cerebrospinal fluid), structural neurodegenerative and cerebrovascular (MRI) variables characterizing sporadic AD-related processes in ADMCI seniors. These results suggest the sex factor may significantly affect neurophysiological brain neural oscillatory synchronization mechanisms underpinning the generation of dominant rsEEG alpha rhythms to regulate cortical arousal during quiet vigilance. | en_US |
dc.description.sponsorship | Ministry of Health, Italy | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Oxford University Press Inc | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Exact Low-Resolution Brain Electromagnetic Source Tomography (eLORETA) | en_US |
dc.subject | Mild Cognitive Impairment due to Alzheimer’s Disease (ADMCI) | en_US |
dc.subject | Resting State Electroencephalographic (rsEEG) Rhythms | en_US |
dc.subject | Sex | en_US |
dc.title | Resting state alpha electroencephalographic rhythms are affected by sex in cognitively unimpaired seniors and patients with alzheimer's disease and amnesic mild cognitive impairment: A retrospective and exploratory study | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Cerebral Cortex | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) | en_US |
dc.department | İstanbul Medipol Üniversitesi, İMÜ Meslek Yüksekokulu, Elektronörofizyoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-0860-0524 | en_US |
dc.authorid | 0000-0002-7715-3035 | en_US |
dc.authorid | 0000-0003-4292-5717 | en_US |
dc.identifier.volume | 32 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.startpage | 2197 | en_US |
dc.identifier.endpage | 2215 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1093/cercor/bhab348 | en_US |
dc.institutionauthor | Güntekin, Bahar | |
dc.institutionauthor | Yıldırım, Ebru | |
dc.institutionauthor | Hanoğlu, Lütfü | |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.wos | 000789377200001 | en_US |
dc.identifier.scopus | 2-s2.0-85128377064 | en_US |
dc.identifier.pmid | 34613369 | en_US |
dc.identifier.scopusquality | Q1 | en_US |