Ara
Toplam kayıt 26, listelenen: 11-20
Rapid molecular diagnosis of group a streptococcus with a novel loop mediated isothermal amplification method
(Verlag Klinisches Labor GmbH, 2022)
Background: Group A Streptococcus (GAS) is the most common bacterial cause of acute tonsillopharyngitis. In this study, it was aimed to evaluate the performance of a novel Loop Mediated Isothermal Amplification (LAMP) ...
Corrosion behavior of hydroxyapatite coated AZ31 and AZ91 Mg alloys by electrostatic spray coating
(Walter de Gruyter GmbH, 2022)
Magnesium and its alloys are excellent implant material candidates with their biodegradable structure and mechanical properties close to human bone. In order to provide the desired strength in implant applications, the ...
The multifactorial role of pre-supplementary motor area stimulation in the freezing of gait: An alternative strategy to the classical drug-Target approach
(Bentham Science Publishers, 2022)
Introduction: The pre-supplementary motor area (Pre-SMA) plays a pivotal role in the control of voluntary motor control and freezing of gait (FOG) pathophysiological mechanism. Here, we aimed to modulate if the pre-SMA ...
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)
Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ...
Biological evaluation of imidazopyridine derivatives as potential anticancer agents against breast cancer cells
(Springer, 2022)
Imidazo[1,2-a]pyridine cores have increasing importance in the pharmaceutical industry with their wide range pharmacological activities. In this study, two series of imidazopyridine derivatives were synthesized. It was ...
Modeling and simulation of the "IL-36 cytokine" and CAR-T cells interplay in cancer onset
(World Scientific, 2022)
Background: CAR-T cells are chimeric antigen receptor (CAR)-T cells; they are target-specific engineered cells on tumor cells and produce T cell-mediated antitumor responses. CAR-T cell therapy is the "first-line" therapy ...
Synthesis and microstructure investigation of Ni40Ti50Cu10 intermetallic shape memory alloys by self-propagating combustion method
(Springer India, 2022)
This study concerns the substitution of copper for nickel in the Ni-Ti system in order to obtain a molar ratio of Ni40Ti50Cu10. Effects of preheating temperature were studied to understand the morphology, phase transformation, ...
Inhibition of SARS-CoV-2 main protease: A repurposing study that targets the dimer interface of the protein
(Taylor and Francis Ltd., 2022)
Coronavirus disease-2019 (COVID-19) was firstly reported in Wuhan, China, towards the end of 2019, and emerged as a pandemic. The spread and lethality rates of the COVID-19 have ignited studies that focus on the development ...
Novel β‑hydroxy ketones: Synthesis, spectroscopic characterization, molecular docking, and anticancer activity studies
(Elsevier B. V., 2022)
In this study, a series of novel β‑hydroxy ketone derivatives 3a-o were designed, synthesized, and evaluated for their anticancer activity. The structure of these compounds were characterized by IR, 1H and 13C NMR, mass ...
Characterization and investigation of properties of copper nanoparticle coated TiO2 nanotube surfaces on Ti6Al4V alloy
(Elsevier Ltd, 2022)
In this work, to investigate surface, corrosion and in vitro biological properties of the CuNPs-coated nanotube surfaces, antibacterial, bioactive and biocompatible nanoparticle-coated nanotube surfaces were produced on ...