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Pure posterior alien hand syndrome following a cerebrovascular lesion: Clinicoradiological correlates
(Korean Neurological Association, 2016)
Dear Editor, Alien hand syndrome (AHS) is a sensation of foreignness between the patient and one of his or her hands, where the affected hand is observed to perform autonomic purposive behaviors that are interpreted as ...
Accelerated forgetting and verbal memory consolidation process in idiopathic nondement Parkinson's disease
(Elsevier, 2019)
Objective: Episodic memory impairment and underlying pathophysiology in Parkinson's Disease (PD) is poorly investigated. Formerly, it was thought to be a secondary effect of impairment in fronto-striatal circuit. However, ...
Abnormalities of resting-state EEG in patients with prodromal and overt dementia with Lewy bodies: Relation to clinical symptoms
(Elsevier Ireland Ltd, 2020)
Objective: Here we tested if cortical sources of resting state electroencephalographic (rsEEG) rhythms may differ in sub-groups of patients with prodromal and overt dementia with Lewy bodies (DLB) as a function of relevant ...
Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
(Wiley, 2017)
Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ...
Pramipexole responsive neck numbness: The therapeutic role of dopamine agonists in the spinal cord indicating to a common spinal pathophysiology with restless leg syndrome (RLS)?
(Bentham Science Publishers, 2016)
Background: There is still speculative data regarding the role of spinal dopaminergic neurotransmission in restless leg syndrome (RLS). Methods: We evaluated the therapeutic role of pramipexole in a patient with cervical ...
Lower extremity tremor exacerbation due to rivastigmine administration for treatment of parkinson’s disease dementia
(2018)
Rivastigmine is one of the approved effective treatments for Parkinson's Disease Dementia (PDD). Increase of upper extremity resting tremor is a common adverse effect seen in patients administered rivastigmine and is usually ...
More evidence for the therapeutic role of pramipexole in upper limb restlessness due to cervical disc pathology?
(Bentham Science Publ Ltd, 2018)
Background: The causal link between upper limb restlessness and cervical disc prolapsus is still unclear, and the exact role of the spinal cord in the origination of limb restlessness is not yet completely understood. ...
Abnormalities of resting state cortical EEG rhythms in subjects with mild cognitive impairment due to alzheimer's and lewy body diseases
(IOS Press, 2018)
The present study tested the hypothesis that cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms reveal different abnormalities in cortical neural synchronization in groups of patients ...
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases
(Elsevier Inc., 2023)
Background: Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are associated with metabolic abnormalities. Integrative analysis of human clinical data and animal studies ...
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: A randomised, double-blinded, placebo-controlled phase-II trial
(BioMed Central Ltd, 2023)
Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed ...