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A review of the fixed dose use of new oral anticoagulants in obese patients: Is it really enough?
(AVES, 2015)
Obesity is a significant cause of morbidity and mortality, and it is becoming increasingly prevalent worldwide. Altered pharmacodynamics and pharmacokinetics of drugs in obese patients require dose adjustment according to ...
Association of ischemia-modified albumin with oxidative stress status and insulin resistance in obese patients
(University Press, 2017)
Objectives: Obesity is associated with oxidative stress due to the overproduction of free radicals in some accompanying states, such as hyperglycemia, elevated lipid levels and chronic inflammation. Free radical accumulation ...
Evaluation of interleukin-6, leukotriene b-4, and nitric oxide levels in exhaled breath condensate of asymptomatic obese individuals: Are obese patients under risk of developing asthma?
(AVES, 2020)
Objective: If systemic inflammation in relation with obesity causes asthma, the detection of increased airwayinflammation among obese individuals who do not have any respiratory symptoms can be also beneficial inindentifying ...
Impaired melanocortin pathway function in prader-willi syndrome gene-magel2 deficient mice
(Oxford University Press, 2018)
Prader-Willi Syndrome (PWS) is a neurodevelopmental disorder causing social and learning deficits, impaired satiety and severe childhood obesity. Genetic underpinning of PWS involves deletion of a chromosomal region with ...
Functional and anatomical dissection of feeding circuits
(Wiley, 2016)
This chapter reviews the application of new genetically encoded tools in feeding circuits that regulate appetite. Rapid activation and inhibition of agouti related peptide (AgRP) neurons conclusively established a causal ...
Obesity might not be a disadvantage for SWL treatment in children with renal stone
(Springer, 2013)
Although the management of urinary stones in obese patients is a challenge and the impact of the patient-related parameter has been well studied in adults: No study has evaluated the possible impact of obesity in terms of ...
Reaktif oksijen türleri ve obezitede oksidatif stres
(Marmara Üniversitesi, 2015)
Obezite; alınan enerjinin, harcanan enerjiden fazla olmasından kaynaklanan, tüm dünyada prevalansı endişe verici şekilde artan kronik bir hastalıktır. Obeziteye neden olan etkenlerden biri olan oksidatif stres, reaktif ...
Is metabolic syndrome associated with obstructive sleep apnea in obese adolescents?
(American Academy of Sleep Medicine, 2015)
Objective: To investigate whether there is an association between metabolic syndrome and obstructive sleep apnea syndrome (OSAS) in obese adolescents. Methods: In total, 240 pubertal children or prepubertal children older ...
Dynamic thiol/disulphide homeostasis as a novel indicator of oxidative stress in obese children and its relationship with inflammatory-cardiovascular markers
(Turkish Society of Cardiology, 2017)
Objective: Childhood obesity is an important cause of cardiovascular risk with chronic inflammation. Oxidative stress may contribute to the pathogenesis of obesity-related cardiovascular pathologies. We aimed to evaluate ...
