Browsing by Author "Yuluğ, Burak"
Now showing items 1-20 of 56
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18F-FDG-PET correlates of ımpulse control disorder in a diabetic patient
Yuluğ, Burak; Hanoğlu, Lütfü; Tavlı, Ahmet Mithat; Çakır, Tansel; Khanmammadov, Elmir; Olmusçelik, Oktay (Bentham Scıence Publ Ltd, 2016)Background: Studies have already shown that hyperglycemia and insulin resistance are significantly associated with the impairment of cerebral glucose metabolism that may secondary lead to cognitive disturbances. In this ... -
Accelerated forgetting and verbal memory consolidation process in idiopathic nondement Parkinson's disease
Hanoğlu, Lütfü; Ercan, Fatma Betül; Mantar, Nagihan; Yılmaz, Nesrin Helvacı; Sitrava, Sevilay; Özer, Feriha F.; Yuluğ, Burak (Elsevier, 2019)Objective: Episodic memory impairment and underlying pathophysiology in Parkinson's Disease (PD) is poorly investigated. Formerly, it was thought to be a secondary effect of impairment in fronto-striatal circuit. However, ... -
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
Çağlayan, Ahmet Burak; Beker, Mustafa Çağlar; Çağlayan, Berrak; Yalçın, Esra; Çağlayan, Aysun; Yuluğ, Burak; Hanoğlu, Lütfü; Kutlu, Selim; Doeppner, Thorsten Roland; Hermann, Dirk Matthias; Kılıç, Ertuğrul (Frontiers Media Sa, 2019)Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ... -
Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-kappa b pathways in traumatic brain injury in mice
Çağlayan, Berrak; Kılıç, Ertuğrul; Dalay, Arman; Altunay, Serdar; Tuzcu, Mehmet; Erten, Füsun; Orhan, Cemal; Günal, Mehmet Yalçın; Yuluğ, Burak; Juturu, Vijaya; Şahin, Kazım (Springer, 2019)Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in young adults and children in the industrialized countries; however, there are presently no FDA approved therapies. TBI results in oxidative ... -
Anterior cerebral artery infarcts; Two years follow-up study
Hanoğlu, Lütfü; Khanmammadov, Elmir; Demirci, Sema; Altın, Ümmühan; Kırbaş, Dursun; Hanoğlu, Taha; Yuluğ, Burak (Literatura Medical, 2018)Objectives - Anterior cerebral infarct (ACA) infarcts are reported very rare that is due to the compensatory collateral circulation provided by the anterior communicating artery. There are very few studies reporting the ... -
Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview
Yuluğ, Burak; Hanoğlu, Lütfü; Khanmammadov, Elmir; Arıcı Düz, Özge; Polat, Burcu; Hanoğlu, Taha; Günal, Mehmet Yalçın; Kılıç, Ertuğrul (Bentham Science Publishers B.V., 2018)Repetitive transcranial magnetic stimulation (rTMS) is a well known non-invasive brain stimulation procedure which is capable of inducing the expression of the hippocampal BDNF that has been already shown to exert significant ... -
The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies
Yuluğ, Burak; Hanoğlu, Lütfü; Tavlı, Ahmet Mithat; Yılmaz Helvacı, Nesrin; Kılıç, Ertuğrul (Bentham Science Publishers, 2016)There are rapidly replicating human data suggesting the therapeutic and neurorestorative role of repetitive transcranial magnetic stimulation (rTMS) in clinical depression. However there are only limited experimental studies ... -
Chemogenetic inhibition of MCH neurons does not alter memory performance in mice
Mutlu Burnaz, Özlem; Yuluğ, Burak; Öncül, Merve; Çelik, Eşref; Sayar Atasoy, Nilüfer; Çankaya, Şeyda; Hanoğlu, Lütfü; Velioğlu, Halil Aziz (Elsevier Masson s.r.l., 2022)Memory storage in the brain is one of the most extensively studied subjects in neuroscience. However, due to the highly complex structure of the memory-related systems in the brain, the mystery remains unsolved. Consolidation ... -
Cinnamon polyphenol extract exerts neuroprotective activity in traumatic brain injury in male mice
Yuluğ, Burak; Kılıç, Ertuğrul; Altunay, Serdar; Ersavaş, Cenk; Orhan, Cemal; Dalay, Arman; Tuzcu, Mehmet; Şahin, Nurhan; Juturu, Vijaya; Şahin, Kazım (Bentham Science Publishers Ltd, 2018)Introduction: Cinnamon polyphenol extract is a traditional spice commonly used in different areas of the world for the treatment of different disease conditions which are associated with inflammation and oxidative stress. ... -
Combination therapy with thrombolysis
Yuluğ, Burak; Schaebitz, Wolf-Ruediger (Springer International Publishing AG, 2017)Thrombolysis is the most effective treatment for acute ischemic stroke representing the basic therapeutic standard in the western world. Novel drug treatments are therefore unlikely to be developed as stand-alone approaches ... -
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: A randomised, double-blinded, placebo-controlled phase-II trial
Yuluğ, Burak; Altay, Özlem; Li, Xiangyu; Hanoğlu, Lütfü; Çankaya, Şeyda; Lam, Simon; Velioğlu, Halil Aziz; Yang, Hong; Coşkun, Ebru; İdil, Ezgi; Nogaylar, Rahim; Özşimşek, Ahmet; Bayram, Cemil; Bolat, İsmail; Öner, Sena; Özdemir Tozlu, Özlem; Arslan, Mehmet Enes; Hacimuftüoğlu, Ahmet; Yıldırım, Serkan; Arif, Muhammad; Shoaie, Saeed; Zhang, Cheng; Nielsen, Jens; Türkez, Hasan; Borén, Jan; Uhlén, Mathias; Mardinoglu, Adil (BioMed Central Ltd, 2023)Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed ... -
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases
Türkez, Hasan; Altay, Özlem; Yıldırım, Serkan; Li, Xiangyu; Yang, Hong; Bayram, Cemil; Bolat, İsmail; Öner, Sena; Özdemir Tozlu, Özlem; Arslan, Mehmet Enes; Arif, Muhammad; Yuluğ, Burak; Hanoğlu, Lütfü; Çankaya, Şeyda; Lam, Simon; Velioğlu, Halil Aziz; Coşkun, Ebru; İdil, Ezgi; Nogaylar, Rahim; Özşimşek, Ahmet; Hacımüftüoğlu, Ahmet; Shoaie, Saeed; Zhang, Cheng; Nielsen, Jens; Borén, Jan; Uhlén, Mathias; Mardinoğlu, Adil (Elsevier Inc., 2023)Background: Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are associated with metabolic abnormalities. Integrative analysis of human clinical data and animal studies ... -
Decreased facial emotion recognition in elderly patients with hearing loss reflects diminished social cognition
Saatçi, Özlem; Geden, Hakan; Güneş Çiftçi, Halide; Çiftçi, Zafer; Arıcı Düz, Özge; Yuluğ, Burak (SAGE Publications Inc, 2022)Objective: The main objective of this research was to evaluate the correlation between the severity of hearing loss and the facial emotional recognition as a critical part of social cognition in elderly patients. Methods: ... -
Depressive disorder after pontine ıschemic stroke: Clinicoradiologic correlates
Yuluğ, Burak; Tavlı, Ahmet Mithat; Çakır, Tansel; Hanoğlu, Lütfü (Amer Psychiatric Publishing, Inc, 2016)It is widely known that the occurrence of poststroke mood disorders, especially depression, is one of the most frequent complications of stroke.1 Studies evaluating the association of focal lesions with depressive disorder ... -
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
Yuluğ, Burak; Ozansoy, Mehmet; Çankaya, Şeyda (Wolters Kluwer, 2019)It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ... -
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
Günal, Mehmet Yalçın; Yuluğ, Burak; Çağlayan, Berrak; Ozansoy, Mehmet; Kılıç, Ülkan; Keskin, İlknur; Kılıç, Ertuğrul (Czech Medical Soc, 2019)Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ... -
DLPF targeted repetitive transcranial magnetic stimulation improves brain glucose metabolism along with the clinical and electrophysiological parameters in CBD patients
Toprak, Güven; Hanoğlu, Lütfü; Çakır, Tansel; Güntekin, Bahar; Velioğlu, Halil Aziz; Yuluğ, Burak (Bentham Science Publishers, 2022)Background: Corticobasal Degeneration (CBD) is a rare neurological disease caused by the pathological accumulation of tau protein. The primary pathological features of CBD include progressive neurodegenerative processes ... -
Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
Yuluğ, Burak; Hanoğlu, Lütfü; Kılıç, Ertuğrul (Wiley, 2017)Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ...
