Browsing by Author "Yeşilada, Erdem"
Now showing items 1-14 of 14
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A comparative investigation on the in vitro anti-inflammatory, antioxidant and antimicrobial potentials of subextracts from the aerial parts of Daphne oleoides Schreb. subsp oleoides
Atay Balkan, İrem; Taşkın, Turgut; Doğan, Hacer Tuğba; Deniz, İnci; Akaydın, Galip; Yeşilada, Erdem (Elsevier, 2017)Daphne oleoides Schreb. subsp. oleoides is an evergreen shrub which is known for its folkloric usage against various ailments such as arthritic and infectious diseases. The aim of the present study was to comparatively ... -
Comparative study of the anti-inflammatory, antioxidant and urease inhibitory activities of Eryngium kotschyi Boiss. and E. campestre L. var. virens (Link) Weins extracts
Atay Balkan, İrem; Taşkın, Turgut; Acar Şah, Esra; Akaydın, Galip; Yeşilada, Erdem (Marmara University Press, 2020)Despite widespread traditional usage of Eryngium species in Anatolia (Turkey), only a limited number of scientific studies exists on E. kotschyi, an endemic species. Previously, extracts from E. campestre and E. kotschyi ... -
Design and synthesis of stable N-[2-(Aryl/heteroaryl substituted)ethyl] propanamide derivatives of (S)-ketoprofen and (S)-ibuprofen as non-ulcerogenic anti-inflammatory and analgesic agents
Berk, Barkın; Bender, Ceysu; Akkol Küpeli, Esra; Yeşilada, Erdem (University of Istanbul, 2016)The carboxylic acid groups of (S) ketoprofen and (S) ibuprofen were brought into reaction with substituted ethylamine derivatives to form (S)-2-(4-isobutylphenyl)- and (S)-2-(3-benzoylphenyl)-N-[2-(aryl/heteroaryl substituted) ... -
The effects of topical liposomal resveratrol on incisional and excisional wound healing process
Günal, Mehmet Yalçın; Ayla, Şule; Bedri, Nejda; Beker, Mustafa Çağlar; Çağlayan, Ahmet Burak; Aslan, İsmail; Özdemir, Ekrem Musa; Yeşilada, Erdem; Kılıç, Ülkan (Turkish Society of Dermatology and Venereology, 2019)Background and Design: The objective of this study was to investigate the wound healing activity of different concentrations of liposomal trans-resveratrol formulations on incisional and excisional wounds in rats. Materials ... -
Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components
Atay Balkan, İrem; Doğan, Hacer Tuba; Zengin, Gökhan; Çolak, Nesrin; Ayaz, Faik Ahmet; Gören, Ahmet Ceyhan; Kırmızıbekmez, Hasan; Yeşilada, Erdem (Elsevier Science Bv, 2018)Oleander (Nerium oleander L., fain: Apocynaceae) is an evergreen shrub. Although it is known to be poisonous to humans, a large number of utilizations in folk medicine have been reported against diabetes, rheumatic pain ... -
Evaluation of in vitro anti-inflammatory effects of the remaining water subextract of Cistus laurifolius leaves
Atay, İrem; İlter, Ayça Zeynep; Bagatur, Yeşim; Telci, Dilek; Kırmızbekmez, Hasan; Yeşilada, Erdem (Georg Thieme Verlag, 2015)Cistus laurifolius L. (Cistaceae) is known as 'laden' in Anatolia and the leaves of the plant are used against rheumatismal diseases traditionally [1]. The ethanol extract of the leaves were submitted to solvent-solvent ... -
Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites
Atay, İrem; Kırmızıbekmez, Hasan; Kaiser, Marcel; Akaydın, Galip; Yeşilada, Erdem; Taşdemir, Deniz (Taylor & Francis Ltd, 2016)Context Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases.Objective In the continuation of our studies on the ... -
Evaluation of the in vitro anti-inflammatory activity of Nerium oleander L. flower extracts and activity-guided isolation of the active constituents
Atay Balkan, İrem; Gören, Ahmet Ceyhan; Kırmızıbekmez, Hasan; Yeşilada, Erdem (ACG Publications, 2018)The in vitro anti-inflammatory activity profile of the Nerium oleander flower EtOH extract/its subextracts (n-hexane, CH2Cl2, EtOAc, remaining H2O) were evaluated on LPS induced Raw 264.7 macrophages. The effects of the ... -
Hemostatic activity of cistus creticus extract in wistar albino rats
Karadağ, Ayşe Esra; Çaşkurlu, Ayşegül; Okur, Mehmet Evren; Güzelmeriç, Etil; Üstündağ Okur, Neslihan; Tosun, Fatma; Yeşilada, Erdem; Demirci, Fatih (Springer Nature, 2020)Aerial part preparations of Cistus creticus L., Cistaceae, are traditionally used in Anatolia as a hemostatic agent. The air-dried aerial parts were extracted with methanol. Gels were prepared, followed by the hemostatic ... -
In vitro bioavailability studies on phytochemical profile and antioxidant activity potential of clematis viticella L.
Acar Şah, Esra; Celep, Engin; Yeşilada, Erdem (Marmara University, 2019)Since biotransformation processes generally affect the biological activities of phytochemical compounds, bioavailability is one of the primary steps in determining the potency of the activity. Previous studies have shown ... -
Isolation of anti-inflammatory compounds from Sambucus ebulus leaves through in vitro activity-guided fractionation
Atay, İrem; İlter, Ayça Zeynep; Bagatur, Yeşim; Telci, Dilek; Gören, Ahmet; Kırmızıbekmez, Hasan; Yeşilada, Erdem (Georg Thieme Verlag, 2015)The in vitro anti-inflammatory effects of subextracts (n-hexane, chloroform, ethyl acetate, n-butanol, remaining water) of the methanol extract of the leaves of Sambucus ebulus L. (Adoxaceae) were investigated for their ... -
A new type of Anatolian propolis: Evaluation of its chemical composition, activity profile and botanical origin
Değirmencioğlu, Hacer Tuğba; Güzelmeriç, Etil; Yüksel, Parla Işıl; Kırmızıbekmez, Hasan; Deniz, İnci; Yeşilada, Erdem (Wiley, 2019)This study was undertaken to analyze the phenolic profiles of 19 propolis samples from Turkey by using a high-performance thin-layer chromatographic (HPTLC) method in order to identify their plant origins. Furthermore, ... -
Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs's phosphorylation
Atay Balkan, İrem; İlter Akülke, Ayça Zeynep; Bağatur, Yeşim; Telci, Dilek; Gören, Ahmet Ceyhan; Kırmızıbekmez, Hasan; Yeşilada, Erdem (Elsevier Irelan Ltd, 2017)Ethnopharmacological relevance: The leaves of Sambucus ebulus L. (Adoxaceae) are widely used in Turkish folk medicine particularly against inflammatory disorders. The fresh leaves after wilted over fire or the poultices ...
