Browsing by Author "Yüce, Meral"
Now showing items 1-15 of 15
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Aptamer and nanomaterial based FRET biosensors: a review on recent advances (2014–2019)
Pehlivan, Zeki Semih; Torabfam, Milad; Kurt, Hasan; Ow-Yang, Cleva; Hildebrandt, Niko; Yüce, Meral (Springer, 2019)Fluorescence resonance energy transfer, one of the most powerful phenomena for elucidating molecular interactions, has been extensively utilized as a biosensing tool to provide accurate information at the nanoscale. Numerous ... -
Characterization of biological molecule–loaded nanostructures using circular dichroism and fourier transform infrared spectroscopy
Parlar, Ayhan; Kulabhusan, Prabir Kumar; Kurt, Hasan; Gürel, Büşra; Torabfam, Milad; Özata, Başak; Yüce, Meral (Taylor and Francis, 2021)Drug-loaded nanoparticles have many advantages in drug administration, which is an essential step for the impact of the drugs and their mechanism of action. Circular dichroism (CD) is a spectroscopy technique that measures ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
Çapkın, Eda; Kurt, Hasan; Gürel, Büşra; Bıçak, Dilan; Akgün Baş, Sibel; Dağlıkoca, Duygu Emine; Yüce, Meral (American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
The efficacy of Staphylococcus aureus dry biomass in the detection of Cd(II) heavy metal ions
Pishva, Parsa; Bayazıt, Mustafa Kemal; Kurt, Hasan; Yüce, Meral (Springer Nature, 2022)Environmental monitoring of heavy metal ions is vital due to their hazardous nature to living organisms. Among them, Cd(II) is a highly carcinogenic ion that interferes with the enzymatic reactions responsible for repairing ... -
Exploiting stokes and anti-stokes type emission profiles of aptamer-functionalized luminescent nanoprobes for multiplex sensing applications
Yüce, Meral; Kurt, Hasan; Hussain, Babar; Ow-Yang, Cleva W.; Budak, Hikmet (Wiley-VCH Verlag Gmbh, 2018)Multiplex biosensing of four types of bacterial food pathogens in one pot is described. Stokes and anti-Stokes type photoluminescence (PL) of two quantum dots (QD) and two upconverting nanoparticles (UCNP) were utilised ... -
Functionalized graphitic carbon nitrides for environmental and sensing applications
Fidan, Tuçe; Torabfam, Milad; Saleem, Qandeel; Wang, Chao; Kurt, Hasan; Yüce, Meral; Tang, Junwang; Bayazıt, Mustafa Kemal (Wiley, 2021)Graphitic carbon nitride (g-C3N4) is a metal-free semiconductor that has been widely regarded as a promising candidate for sustainable energy production or storage. In recent years, g-C3N4 has become the center of attention ... -
How to make nanobiosensors: Surface modification and characterisation of nanomaterials for biosensing applications
Yüce, Meral; Kurt, Hasan (Royal Society of Chemistry, 2017)This report aims to provide the audience with a guideline for construction and characterisation of nanobiosensors that are based on widely used affinity probes including antibodies and aptamers and nanomaterials such as ... -
A microwave-powered continuous fluidic system for polymer nanocomposite manufacturing: A proof-of-concept study
Torabfam, Milad; Nejatpour, Mona; Fidan, Tuçe; Kurt, Hasan; Yüce, Meral; Bayazıt, Mustafa Kemal (Royal Society of Chemistry, 2022)Continuous manufacturing of pure nanocrystals with a narrow size distribution in a polymer matrix is very challenging, although it is highly crucial to get their full potential for advanced applications. A long-lasting ... -
Microwave-promoted continuous flow synthesis of thermoplastic polyurethane-silver nanocomposites and their antimicrobial performance
Saleem, Qandeel; Torabfam, Milad; Kurt, Hasan; Yüce, Meral; Bayazıt, Mustafa Kemal (Royal Society of Chemistry, 2022)Thermoplastic polyurethane-silver nanocomposites (PU-Ag NCs) have considerable potential in many medical applications due to their superior mechanical and antimicrobial properties. Herein, a microwave-promoted flow system ... -
Microwave-promoted continuous flow systems in nanoparticle synthesis-A perspective
Saleem, Qandeel; Torabfam, Milad; Fidan, Tuçe; Kurt, Hasan; Yüce, Meral; Clarke, Nigel; Bayazıt, Mustafa Kemal (American Chemical Society, 2021)Microwave-promoted continuous flow systems have emerged as a game-changer in nanoparticle synthesis. Owing to the excellent compatibility between fast, sustainable microwave heating and one-step, efficient flow chemistry, ... -
Nanoplasmonic biosensors: Theory, structure, design, and review of recent applications
Kurt, Hasan; Pishva, Parsa; Pehlivan, Zeki Semih; Arsoy, Elif Gül; Saleem, Qandeel; Bayaz, Mustafa Kemal; Yüce, Meral (Elsevier, 2021)Nanoplasmonic biosensing shows an immense potential to satisfy the needs of the global health industry -low-cost, fast, and portable automated systems; highly sensitive and real-time detection; multiplexing and miniaturization. ... -
Plasmonic selection of ssDNA aptamers against fibroblast growth factor receptor
Kurt, Hasan; Eyüpoğlu, Alp Ertunga; Sütlü, Tolga; Budak, Hikmet; Yüce, Meral (American Chemical Society, 2019)In this work, we describe the selection of ssDNA aptamers targeting fibroblast growth factor receptor binding protein 3 K650E, which has roles in cell division, growth, and differentiation through the kinase cascade. The ... -
SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers
Yılmaz, Deniz; Muslu, Tuğdem; Parlar, Ayhan; Kurt, Hasan; Yüce, Meral (Elsevier B.V., 2022)Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial libraries through an iterative in vitro screening process known as Systemic Evolution of Ligands by Exponential Enrichment (SELEX). In ... -
Systematic evolution of ligands by exponential enrichment for aptamer selection
Yüce, Meral; Kurt, Hasan; Hussain, Babar; Budak, Hikmet (Elsevier, 2018)Discovery of aptamers and developments in the field of nanotechnology has made a significant contribution to the field of biosensing. Nanomaterials with various physical, optic, and electronic properties have been ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
Sert, Fatma; Hız, Defne; Gülmez, Mert; Cankurtaran, Selen Ezgi; Kayalan, Cemre Irmak; Kurt, Hasan; Yüce, Meral (MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ...
