Browsing by Author "Uysal, Ömer"
Now showing items 1-9 of 9
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Delayed therapeutic administration of melatonin enhances neuronal survival through AKT and MAPK signaling pathways following focal brain ischemia in mice
Kılıç, Ülkan; Elibol, Birsen; Çağlayan, Ahmet Burak; Beker, Mustafa Çağlar; Beker, Merve; Altuğ Tasa, Burcugül; Uysal, Ömer; Yılmaz, Bayram; Kılıç, Ertuğrul (Springer Nature, 2022)Melatonin has a role in the cell survival signaling pathways as a candidate for secondary stroke prevention. Therefore, in the present study, the coordination of ipsilateral and contralateral hemispheres to evaluate delayed ... -
The effects of human amniotic membrane on silicone related capsule formation in rats
Akyürek, Mustafa; Orhan, Erkan; Aydın, Mehmet Şerif; Uysal, Ömer; Karşıdağ, Semra (Taylor and Francis Ltd., 2020)Silicone breast implants are commonly used materials in plastic surgery for breast augmentation and reconstruction and the most severe complication of silicone implants are capsule contraction which occurs in 40% of patients. ... -
Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease
Gangarapu, Venkatanarayana; Tüzün İnce, Ali; Baysal, Birol; Kayar, Yusuf; Kılıç, Ülkan; Gök, Özlem; Uysal, Ömer; Şentürk, Hakan (Lippincott Williams and Wilkins, 2015)ObjectiveRecent studies have suggested that endotoxin-induced cytokines play an important role in nonalcoholic fatty liver disease (NAFLD). Rifaximin is a nonabsorbable antibiotic that might act on Gram-negative bacteria, ... -
Efficacy of statins on sirtuin 1 and endothelial nitric oxide synthase expression: The role of sirtuin 1 gene variants in human coronary atherosclerosis
Kılıç, Ülkan; Gök, Özlem; Elibol, Birsen; Uysal, Ömer; Bacaksız, Ahmet (Wiley, 2015)Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and are used to reduce the risk of coronary artery disease (CAD) due to their pleiotropic effects. Recently, greater focus has been placed on the role ... -
Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives
Başaranoğlu, Metin; Canbakan, Billur; Yıldız, Kemal; Ceylan, Bahadır; Baysal, Birol; Uysal, Ömer; Şentürk, Hakan (AVES, 2014)Background/Aims: We investigated the risk of abdominal operation in patients with fatty liver and the risk of any cancer in first-degree relatives of patients with fatty liver. Materials and Methods: We evaluated 105 ... -
Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives (Retraction of vol 25, pg 138, 2014)
Başaranoğlu, Metin; Canbakan, Billur; Yıldız, Kemal; Ceylan, Bahadır; Baysal, Birol; Uysal, Ömer; Şentürk, Hakan (Aves, 2015)… -
A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human
Kılıç, Ülkan; Gök, Özlem; Erenberk, Ufuk; Dündaröz, Mehmet Ruşen; Torun, Emel; Küçükardalı, Yaşar; Elibol, Birsen; Uysal, Ömer; Dündar, Tolga Turan (Public Library of Science, 2015)Aging is defined as the accumulation of progressive organ dysfunction. Controlling the rate of aging by clarifying the complex pathways has a significant clinical importance. Nowadays, sirtuins have become famous molecules ... -
SIRT1 gene variants are related to risk of childhood obesity
Kılıç, Ülkan; Gök, Özlem; Elibol, Birsen; Özgen, İlker Tolga; Erenberk, Ufuk; Uysal, Ömer; Dündaröz, Mehmet Ruşen (Springer, 2015)Obesity is a multifactorial disorder resulting from the interaction between genetic, psychological, physical, environmental, and socioeconomic factors. SIRT1 gene has important effects on the regulation of adiponectin, ... -
Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia
Kılıç, Ülkan; Elibol, Birsen; Uysal, Ömer; Kılıç, Ertuğrul; Yuluğ, Burak; Sayın Şakul, Arzu; Babacan Yıldız, Gülşen (Pergamon Elsevier Science Ltd, 2018)Sirtuins have gained considerable attention as epigenetic regulators for slowing aging and age-related disorders. The growing association between neurodegeneration and inflammation has led researchers to investigate ...