Browsing by Author "Tok, Olgu Enis"
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The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
Söylemez, Esra; Özçağlı, Eren; Korkmaz, Serol; Tok, Olgu Enis; Aydın, Mehmet Şerif; Omurtag, Gülden Zehra (SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Cannabidiol as a potential novel treatment for endometriosis by its anti-inflammatory, antioxidative and antiangiogenic effects in an experimental rat model
Ökten, Sabri Berkem; Çetin, Çağlar; Tok, Olgu Enis; Güler, Eray Metin; Taha, Sevde Havva; Özcan, Pınar; Fıçıcıoğlu, Cem (Elsevier Science Ltd, 2023)Research question: Can cannabidiol (CBD) be used in the treatment of endometriosis for its anti-inflammatory, antioxidative and antiangiogenic effects? Design: Endometrial implants were surgically induced in 36 female ... -
Comparison of 3 cell-free matrix scaffolds used to treat osteochondral lesions in a rabbit model
Demir, Ahder İrem; Pulatkan, Anıl; Uçan, Vahdet; Yılmaz, Bengi; Tahmasebifar, Aydın; Tok, Olgu Enis; Tuncay, İbrahim; Elmalı, Nurzat; Öztürk, Burak Yağmur; Uzer, Gökçer (SAGE Publications Inc., 2022)Background: Various cell-free scaffolds are already in use for the treatment of osteochondral defects (OCDs); however, a gold standard material has not yet been defined. Purpose: This study compared the macroscopic, ... -
Culturing, freezing, processing, and imaging of entire organoids and spheroids while still in a hydrogel
Tok, Olgu Enis; Demirel, Gamze; Saatçi, Yusuf; Akbulut, Zeynep; Kayalar, Özgecan; Aktaş, Ranan Gülhan (Journal of Visualized Experiments, 2022)Organoids and spheroids, three-dimensional growing structures in cell culture labs, are becoming increasingly recognized as superior models compared to two-dimensional culture models, since they mimic the human body better ... -
Effect of salvianolic acid B on new bone formation in the orthopedically expanded suture: A histological and immunohistochemical study
Kayalar, Emre; Taş Deynek, Gül; Tok, Olgu Enis; Küçük, Sevim (E H Angle Education Research Foundation, Inc., 2021)Objectives: To determine the effects of Salvianolic acid B (Sal B) on new bone formation in the orthopedically expanded premaxillary sutures in rats.Materials and Methods: The sample consisting of Sprague Dawley rats (male, ... -
Effects of cichorium intybus on GABA(A) receptors and apoptosis in pentylenetetrazole-induced kindling in rats
Ergül Erkeç, Özlem; Meral, İsmail; Kara, Mehmet; Eşrefoğlu, Mukaddes; Tok, Olgu Enis; Üstünova, Savaş; Armağan, Metin (Kare Publishing, 2021)Objectives: This study was designed to determine the effects of Cichorium intybus (CI) on apoptosis and GABA(A) receptor density in the brains of rats in pentyleneterazole induced kindling. Methods: The rats were divided ... -
Effects of melatonin on both testicular regeneration and recovery of spermatogenesis in busulfan-treated rats
Taşlıdere, Elif; Eşrefoğlu, Mukaddes; Tok, Olgu Enis; Taşlıdere, Bahadır; Bulut, Huri (Faculdade de Ciencias Farmaceuticas (Biblioteca), 2022)Testicular damage is one of the most hazardous effects of chemotherapy as it is frequently associated with oligozoospermia and azoospermia. This study aimed at evaluating the protective effect of melatonin in a rat model ... -
Effects of platelet rich plasma and amniotic cell culture medium on wound healing following experimental animal tracheal injury model: A comparative study
Mirapoğlu, Semih; Güler, Eray Metin; Tok, Olgu Enis; Aydoğdu, İbrahim; Çay, Ali; Çamlı, Mehmet; Koçyiğit, Abdurrahim; Canter, Halil İbrahim; Yıldız, Kemalettin (Lippincott Williams & Wilkins, 2021)Introduction: Prolonged inflammation after tracheal injury invariably results in a degree of stenosis. The topical application of platelet-rich plasma (PRP) and human amniotic fluid-derived cell culture medium (ACCM) have ... -
The effects of transcranial focused ultrasound stimulation of nucleus accumbens on neuronal gene expression and brain tissue in high alcohol-preferring rats
Deveci, Erdem; Akbaş, Fahri; Ergün, Arif Şanlı; Kurtulmuş, Ayşe; Koçak, Ali Barlas; Boyraz, Rabia Kevser; Tok, Olgu Enis; Aydın, Mehmet Şerif; Kılıç, Özge; Bozkurt, Ayhan; Uysal, Ömer; Eşrefoğlu, Mukaddes (Springer, 2023)We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histological effects on brain tissue. We also aimed at determining the miRNA-mRNA relationship and ... -
The efficiency of ozone therapy and low-level laser therapy in rat facial nerve injury
Yuca, Yusuf; Yücesoy, Türker; Tok, Olgu Enis; Alkan, Alper (Churchill Livingstone, 2020)Purpose: Comparison of low-level laser therapy (LLLT) and ozone therapy (OT) methods for the treatment of facial nerve injury (FNI) in rats, evaluated by histomorphometric measurement analysis. Materials and methods: Thirty ... -
New bone-generative effect of Salvia officinalis L. in the expanded midpalatal suture An in vivo and in vitro study
Kayalar, Emre; Göger, Fatih; Taş Deynek, Gül; Tok, Olgu Enis; Küçük, Sevim (Urban & Vogel, 2022)Purpose The aims of this study were to evaluate the effects of systemic administration of Salvia officinalis Linnaeus (L.) leaf extract on new bone formation in the expanded premaxillary suture in rats in vivo and to examine ... -
The protective effect of platelet-rich plasma administrated on ovarian function in female rats with Cy-induced ovarian damage
Özcan, Pınar; Takmaz, Taha; Tok, Olgu Enis; İşlek, Sevde; Yiğit, Esra Nur; Fıçıcıoğlu, Cem (Springer, 2020)Purpose We evaluated the protective effect of PRP on ovarian function in female rats with cyclophosphamide (Cy)-induced ovarian damage. Methods Thirty-two adult female Sprague-Dawley rats were randomly divided into four ... -
Radyoterapiyi takiben kritik boyutta oluşturulan kemik defektlerinde antibiyotiklerin etkinliğinin deneysel olarak incelenmesi
Günay, Özgün; Doğanay, Özge; Tok, Olgu Enis; Alkan, Alper (2020)Amaç: Çenelerin osteoradyonekrozu (ORN), baş ve boyun kanserlerinde radyasyon tedavisinin bir komplikasyonu olarak karşımıza çıkmaktadır. Tanımı ve sınıflandırması yıllar içinde değişiklik göstermiş, patofizyolojisine dair ...
