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Antioxidant activity of CAPE (Caffeic Acid Phenethyl Ester) in vitro can protect human sperm deoxyribonucleic acid from oxidative damage
Ayla, Şule; Tunalı, Gülden; Bilgiç, Bülent Emre; Sofuoğlu, Kenan; Özdemir, A. Arman; Tanrıverdi, Gamze; Özdemir, Semra; Soner, Burak Cem; Öztürk, Bahar; Karahüseyinoğlu, Serçin; Aslan, Esra; Seçkin, İsmail (Elsevier GmbH, 2018)Purpose: Sperm processing (e.g., centrifugation) used in preparation for assisted reproduction can result in excessive generation of reactive oxygen species (ROS) and potential sperm damage. The use of antioxidants during ... -
Effects of different drug treatments on the proliferation of human ovarian carcinoma cell line MDAH-2774
Ayla, Şule; Bilir, Ayhan; Ertürkoğlu, Şenol; Tanrıverdi, Gamze; Soner, Burak Cem; Sofuoğlu, Kenan; Ghisolfi, Laura; Öktem, Gülperi (Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: In this study, the effects of resveratrol as a natural polyphenol compound, gemcitabine as an antimetabolite that has nucleoside structure analogous to deoxycytidine, and para-aminophenol-derived paracetamol ... -
Neuroprotective effect of intrastriatal caffeic acid phenethyl ester treatment in 6-oh dopamine model of parkinson's disease in rats
Soner, Burak Cem; Açıkgöz, Eda; İnan, Salim Yalçın; Ayla, Şule; Şahin, Ayşe Saide; Öktem, Gülperi (Hindawi Ltd, 2021)Parkinson's disease (PD) is the second most common neurodegenerative disorder, and the main cause of PD is still not known. Until now, no cure for Parkinson's disease is yet in sight. Caffeic acid phenethyl ester (CAPE) ...