Browsing by Author "Sibai, Mustafa"
Now showing items 1-7 of 7
-
Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl
Sibai, Mustafa; Altuntaş, Ebru; Süzek, Barış Ethem; Şahin, Betül; Parlayan, Cüneyd; Öztürk, Gürkan; Baykal, Ahmet Tarık; Demircan, Turan (Elsevier, 2020)The axolotl (Ambystoma mexicanum) salamander, a urodele amphibian, has an exceptional regenerative capacity to fully restore an amputated limb throughout the life-long lasting neoteny. By contrast, when axolotls are ... -
The first report on circulating microRNAs at Pre- and Post-metamorphic stages of axolotls
Demircan, Turan; Sibai, Mustafa; Avşaroğlu, Mahmut Erhan; Altuntaş, Ebru; Ovezmyradov, Guvanch (Elsevier, 2021)MicroRNAs (miRNAs) are endogenously coded small RNAs, implicated in post-transcriptional gene regulation by targeting messenger RNAs (mRNAs). Circulating miRNAs are cell-free molecules, found in body fluids, such as blood ... -
Integrative analysis of axolotl gene expression data from regenerative and wound healing limb tissues
Sibai, Mustafa; Parlayan, Cüneyd; Tuğlu, Pelin; Öztürk, Gürkan; Demircan, Turan (Nature Research, 2019)Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ... -
An integrative gene-expression analysis of axolotl limb wound healing and regeneration
Sibai, Mustafa (İstanbul Medipol Üniversitesi Fen Bilimleri Enstitüsü, 2019)Axolotl is a member of the urodele amphibians that exhibits extraordinary regenerative and scarless wound healing capabilities, fully restoring a lost limb as well as efficiently healing a damaged one. Axolotl has recently ... -
Microbiome and longevity: High abundance of longevity-linked muribaculaceae in the gut of the long-living rodentspalax leucodon
Sibai, Mustafa; Altuntaş, Ebru; Yıldırım, Berna; Öztürk, Gürkan; Yıldırım, Süleyman; Demircan, Turan (Mary Ann Liebert Inc, 2020)With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the ... -
Preclinical molecular signatures of spinal cord functional restoration: Optimizing the metamorphic axolotl (ambystoma mexicanum) model in regenerative medicine
Demircan, Turan; Hacıbektaşoğlu, Harbiye; Sibai, Mustafa; Cana Fesçioğlu, Ece; Altuntaş, Ebru; Öztürk, Gürkan; Süzek, Barış Ethem (Mary Ann Liebert, 2020)Regenerative medicine offers hope for patients with diseases of the central and peripheral nervous system. Urodele amphibians such as axolotl display an exceptional regenerative capacity and are considered as essential ... -
Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages
Demircan, Turan; Sibai, Mustafa; Altuntaş, Ebru (Elsevier, 2020)The presented data article reports protein expression profiles during a time course of limb regeneration in the highly regenerative neotenic and regeneration-deficient metamorphic axolotl (Ambystoma mexicanum). A protein ...
