Browsing by Author "Siafaka, Panoraia I."
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An alternative approach to wound healing field; New composite films from natural polymers for Mupirocin dermal delivery
Okur, Neslihan Üstündağ; Hökenek, Nesrin; Okur, Mehmet Evren; Ayla, Şule; Yoltaş, Ayşegül; Siafaka, Panoraia I.; Cevher, Erdal (Elsevier, 2019)In this study, novel adhesive films were prepared for Mupirocin dermal delivery. Natural polymers as chitosan, sodium alginate and carbopol were used for films development to evaluate possible interactions and drug release ... -
Antibacterial evaluation of elettaria cardamomum (L.) Maton, Lavandula angustifolia mill. and salvia fruticosa mill. essential oil combinations in mouthwash preparations
Karadağ, Ayşe Esra; İpekçi, Esra; Yağcılar, Ayşe Pınar; Demirbolat, İlker; Kartal, Murat; Siafaka, Panoraia I.; Üstündaǧ Okur, Neslihan (Badebio Biotechnololgy Ltd, 2020)The aim of this present study was to evalute Elettaria cardamomum (L.) Maton., Lavandula angustifolia Mill. and Salvia fruticosa Mill. essential oils in mouthwashes formulated with different combinations such as 0.1/0.25/0.1; ... -
Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: Current status and applications
Siafaka, Panoraia I.; Özcan Bülbül, Ece; Dilsiz, Pelin; Karantas, Ioannis D.; Okur, Mehmet Evren; Üstündağ Okur, Neslihan (Taylor & Francis Ltd, 2021)Neurodegeneration is defined as the progressive atrophy and loss of function of neurons; it is present in neurodegenerative disorders such as Multiple Sclerosis, Alzheimer's, Huntington's, and Parkinson's diseases. The ... -
Phytochemical compounds loaded to nanocarriers as potential therapeutic substances for alzheimer’s disease-could they be effective?
Polat, Derya Çiçek; Karadağ, Ayşe Esra; Parlar Köprülü, Rabia Edibe; Karantas, Ioannis D.; Mutlu, Gökçe; Çağlar, Emre Şefik; Okur, Mehmet Evren; Üstündağ Okur, Neslihan; Siafaka, Panoraia I. (Bentham Science Publishers, 2022)Alzheimer's disease accounts for a high percentage of dementia cases in elderly individuals. This type of brain disease is caused by damage to the brain cells affecting the ability of the patients to communicate, as well ... -
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
Siafaka, Panoraia I.; Okur, Mehmet Evren; Dilsiz Erim, Pelin; Çağlar, Emre Şefik; Özgenç, Emre; Gündoğdu, Evren; Parlar Köprülü, Rabia Edibe; Karantaş, Ioannis D.; Üstündağ Okur, Neslihan (MDPI, 2022)It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ... -
Surface modified multifunctional and stimuli responsive nanoparticles for drug targeting: Current status and uses
Siafaka, Panoraia I.; Okur Üstündağ, Neslihan; Karavas, Evangelos; Bikiaris, Dimitrios N. (MDPI, 2016)Nanocarriers, due to their unique features, are of increased interest among researchers working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules, involving non-toxic biodegradable polymers, ... -
Two different approaches for oral administration of voriconazole loaded formulations: Electrospun fibers versus beta-cyclodextrin complexes
Siafaka, Panoraia I.; Okur Üstündağ, Neslihan; Mone, Mariza; Giannakopoulou, Spyridoula; Er, Sevda; Pavlidou, Eleni; Karavas, Evangelos; Bikiaris, Dimitrios N. (MDPI, 2016)In this work, a comparison between two different preparation methods for the improvement of dissolution rate of an antifungal agent is presented. Poly(epsilon-caprolactone) (PCL) electrospun fibers and beta-cyclodextrin ...