Browsing by Author "Seymen, Figen"
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8-12 yaş arası çocuklarda görülen kötü ağız alışkanlıklarının sıklığı
Yıldırım, Mine; Bayram, Merve; Patır, Aslı; Yalçın, Ferhan; Seymen, Figen (Istanbul University Press, 2011)Bu çalışmanın amacı, 8-12 yaşları arasındaki çocuklarda kötü ağız alışkanlıklarının sıklığının değerlendirilmesi ve sonuçlarının yaşa ve ağız sağlığına göre karşılaştırılmasıdır. Yaşları 8 ile 12 arasında değişen 107 çocuk ... -
Alteration of exon definition causes amelogenesis imperfecta
Kim, Young-jae; Kang, Jenny; Seymen, Figen; Koruyucu, Mine; Zhang, Hong; Kasımoǧlu, Yelda; Bayram, Merve; Tuna-İnce, Elif Bahar; Bayrak, Şule; Tüloğlu, Nuray; Hu, Jan C.; Simmer, James P.; Kim, Jung-Wook (SAGE Publications Inc., 2020)Amelogenesis imperfecta (AI) is a collection of genetic disorders affecting the quality and/or quantity of tooth enamel. More than 20 genes are, so far, known to be responsible for this condition. In this study, we recruited ... -
Aquaporin 5 interacts with fluoride and possibly protects against caries
Anjomshoaa, Ida; Briseno-Ruiz, Jessica; Deeley, Kathleen; Poletta, Fernardo; Mereb, Juan; Leite, Aline; Barreta, Priscila; Silva, Thelma; Dizak, Piper; Ruff, Timothy; Patır, Aslı; Koruyucu, Mine; Abbasoğlu, Zerrin; Casado, Priscila; Brown, Andrew; Zaky, Samer; Bayram, Merve; Kuechler, Erika; Cooper, Margaret; Liu, Kai; Marazita, Mary; Tanboğa, İlknur; Granjeiro, Jose; Seymen, Figen; Castilla, Eduardo; Orioli, Ieda; Sfeir, Charles; Owyang, Hongjiao; Buzalaf, Marilia; Vieira, Alexandre (Public Library of Science, 2015)Aquaporins (AQP) are water channel proteins and the genes coding for AQP2, AQP5, and AQP6 are clustered in 12q13. Since AQP5 is expressed in serous acinar cells of salivary glands, we investigated its involvement in caries. ... -
Candidate gene studies in hypodontia suggest role for FGF3
Vieira, Alexandre Rezende; D'Souza, Rena; Mues, Gabriele; Deeley, Kathleen; Hsin, Hongyuan; Küchler, Erika Calvano; Meira, Raquel; Patır, Aslı; Tannure, Patrícia Nivoloni; Lips, Andrea; Meneghim, Marcelo de Castro; Granjeiro, José Mauro; Seymen, Figen; Modesto, Adriana (2013)Introduction The majority of tooth agenesis cases are mild (hypodontia) and typically not associated with the gene mutations linked to oligodontia. From this, we hypothesise that most cases of tooth agenesis fit a polygenic ... -
Clinical and oral findings of a patient with Simpson-Golabi-Behmel syndrome
Bayram, Merve; Yıldırım, Mine; Seymen, Figen (Springer, 2015)Background The Simpson-Golabi-Behmel syndrome (SGBS) is an overgrowth condition characterised by macrosomia, mental deficiency, large head, prominent skull sutures, midface deficiency, hypertelorism, broad nose, wide mouth, ... -
Comparison of root canal length measurement methods in primary teeth
Koruyucu, Mine; Bayram, Merve; Kasımoǧlu, Yelda; Seymen, Figen (University Library System, University of Pittsburgh, 2018)Objectves: The purpose of this study was to evaluate the accuracy of conven5onal radiography, intraoral digital radi- ovisiography and electronic apex locator in determining the working length of root canals in primary ... -
Enamel formation genes influence enamel microhardness before and after cariogenic challenge
Shimizu, Takehiko; Ho, Bao; Deeley, Kathleen; Briseno-Ruiz, Jessica; Faraco, Italo Medeiros; Schupack, Brett Ian; Brancher, Joäo Armando; Pecharki, Giovana Daniela; Küchler, Erika Calvano; Tannure, Patrícia Nivoloni; Lips, Andrea; Vieira, Thays Cristinedos Santos; Patır, Aslı; Yıldırım, Mine; Poletta, Fernando Adrián; Mereb, Juan Carlos; Resick, Judith M.; Brandon, Carla A.; Orioli, Ieda M.; Castilla, Eduardo Enrique; Marazita, Mary Louise; Seymen, Figen; Costa, Marcelo Costra; Granjeiro, José Mauro; Trevilatto, Paula Cristina; Vieira, Alexandre Rezende (Public Library Science, 2012)There is evidence for a genetic component in caries susceptibility, and studies in humans have suggested that variation in enamel formation genes may contribute to caries. For the present study, we used DNA samples collected ... -
Estetik restoratif materyallerin cila işlemlerinden sonra yüzey yapısının sem ile incelenmesi
Yıldırım, Mine; Patır, Aslı; Seymen, Figen; Gençay, Koray (Atatürk Üniversitesi, 2012)Amaç: Bu çalışmanın amacı, ışıkla polimerize olan iki farklı cam iyonomer materyali ile iki farklı posterior bölge kompozit materyalinin yüzey özelliklerini cila işlemleri uygulandıktan sonra analiz etmektir. Gereç-Yöntem: ... -
Fine mapping of locus Xq25.1-27-2 for a low caries experience phenotype
Küchler, Erika Calvano; Feng, Ping; Deeley, Kathleen; Fitzgerald, Carly A.; Meyer, Chelsea; Gorbunov, Anastasia; Bezamat, Mariana; Reis, Maria Fernanda; Noel, Jacqueline; Kouzbari, M. Zahir; Granjeiro, Jose Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Vieira, Alexandre Rezende (Pergamon-Elsevier Science Ltd., 2014)Objective: The purpose of this study was to fine map the locus Xq25.1-27-2 in order to identify genetic contributors involved in low caries experience. Design: Seventy-two families from the Philippines were studied. Caries ... -
Fine-Mapping of 5q12.1-13.3 unveils new genetic contributors to caries
Shimizu, Takehiko; Deeley, Kathleen; Briseno Ruiz, Jessica; Faraco, Italo Medeiros; Poletta, Fernando Adrian; Brancher, Joao Armando; Pecharki, Giovana Daniela; Kuechler, Erika Calvano; Tannure, Patricia Nivoloni; Lips, Andrea; Vieira, Thays Cristinedos Santos; Patır, Aslı; Yıldırım, Mine; Mereb, Juan Carlos; Resick, Judith; Brandon, Carla; Cooper, Margaret; Seymen, Figen; Costa, Marcelo de Castro; Granjeiro, Jose Mauro; Trevilatto, Paula Cristina; Orioli, Ieda Maria; Castilla, Eduardo Enrique; Marazita, Mary Louise; Vieira, Alexandre Rezende (Karger, 2013)Caries is a multifactorial disease and little is still known about the host genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified the interval 5q12.1-5q13.3 as linked to low caries ... -
Gene-environment interaction in molar-incisor hypomineralization
Bezamat, Mariana; Souza, Juliana Feltrin de; Silva, Fernanda M.F.; Corrêa, Emilly G.; Fatturi, Aluhê Lopes; Brancher, Joäo Armando; Carvalho, Flávia M.; Cavallari, Tayla; Bertolazo, Laís; Machado-Souza, Cleber; Koruyucu, Mine; Bayram, Merve; Racic, Andrea; Harrison, Benjamin M.; Sweat, Yan Yan; Letra, Ariadne; Studen-Pavlovich, Deborah A.; Seymen, Figen; Amendt, Brad A.; Iani Werneck, Renata; Costa, Marcelo C.; Modesto, Adriana M.; Vieira, Alexandre Rezende (Public Library of Science, 2021)Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. ... -
Genetic influences on dental enamel that impact caries differ between the primary and permanent dentitions
Bayram, Merve; Deeley, Kathleen; Reis, Maria; Trombetta, Vanessa; Ruff, Timothy; Sencak, Regina; Hummel, Michael; Dizak, Piper; Washam, Kelly; Romanos, Helena; Lips, Andrea; Alves, Gutemberg; Costa, Marcelo; Granjeiro, Jose; Antunes, Leonardo; Kuechler, Erika; Seymen, Figen; Vieira, Alexandre (Wiley, 2015)Clinically, primary and permanent teeth are distinct anatomically and the presentation of caries lesions differs between the two dentitions. Hence, the possibility exists that genetic contributions to tooth formation of ... -
Genetic mapping of high caries experience on human chromosome 13
Küchler, Erika Calvano; Deeley, Kathleen; Ho, Bao; Linkowski, Samantha; Meyer, Chelsea; Noel, Jacqueline; Kouzbari, M. Zahir; Bezamat, Mariana; Granjeiro, José Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Mereb, Juan Carlos; Poletta, Fernando Adrián; Castilla, Eduardo Enrique; Orioli, Iêda Maria; Marazita, Mary Louise; Vieira, Alexandre Rezende (BMC, 2013)Background: Our previous genome-wide linkage scan mapped five loci for caries experience. The purpose of this study was to fine map one of these loci, the locus 13q31.1, in order to identify genetic contributors to caries. ... -
Genetic polymorphisms influence shear bond resistance of orthodontic brackets
Randazzo, Adam C.; Burnheimer, John M.; Bayram, Merve; Seymen, Figen; Vieira, Alexandre Rezende (Elsevier, 2020)Objectives: The purpose of this study was to determine if shear bond resistance of orthodontic brackets bonded to enamel is associated with genes implicated in the enamel mineralization process.Methods: Ninety-two permanent, ... -
In vitro acid-mediated initial dental enamel loss is associated with genetic variants previously linked to caries experience
Vieira, Alexandre R.; Bayram, Merve; Seymen, Figen; Sencak, Regina C.; Lippert, Frank; Modesto, Adriana (Frontiers Media S.A., 2017)We have previously shown that AQP5 and BTF3 genetic variation and expression in whole saliva are associated with caries experience suggesting that these genes may have a functional role in protecting against caries. To ... -
Investigating the level of knowledge of the community about oral and dental health
Birant, Sinem; Koruyucu, Mine; Özcan, Hazal; İlisulu, Ceren; Kasımoğlu, Yelda; Üstün, Nilüfer; Kocaaydın, Simin; Bektaş, Dilara; Usta, Gülsevim; Akay Tekin, Cansu; Bekiroğlu, Nural; Seymen, Figen (Georg Thieme Verlag, 2021)Objectives This study aimed to determine the knowledge and approaches of the participants about oral and dental health. Materials and Methods This was a questionnaire-based cross-sectional survey. Participants' demographic ... -
Investigation of surface topography of different root-end filling materials: an in vitro study
Koruyucu, Mine; Özcan, Hazal; Bayram, Merve; Çankaya, Abdullah Burak; Keklikoǧlu, Nurullah; Seymen, Figen (University Library System, University of Pittsburgh, 2019)Aim: Although there are many materials that can be used for retrograde filling in surgical endodontics, none of them can be regarded as an ideal material yet. The purpose of this study was to compare the surface topography ... -
Mutations in RELT cause autosomal recessive amelogenesis imperfecta
Kim, Jung-Wook; Zhang, Hong; Seymen, Figen; Koruyucu, Mine; Hu, Yuanyuan; Kang, Jenny; Kim, Youn Ju; Ikeda, Atsushi; Kasımoğlu, Yelda; Bayram, Merve; Zhang, Chuhua; Kawasaki, Kazuhiko; Bartlett, John D.; Saunders, Thomas L.; Simmer, James P.; Hu, Jan C-C. (Wiley, 2019)Amelogenesis imperfecta (AI) is a collection of isolated (non-syndromic) inherited diseases affecting dental enamel formation or a clinical phenotype in syndromic conditions. We characterized three consanguineous AI families ... -
Orthodontic treatment needs of children: Comparison of three index
Koruyucu, Mine; İnce Tuna, Elif Bahar; Seymen, Figen; Münevveroğlu Patır, Aslı; Acar, Gözde (Istanbul University, 2014)Purpose: An orthodontic treatment need index is a form of occlusal index devised initially to prioritize the need for treatment and to categorize the malocclusion and identify patients based upon treatment need. The aim ... -
Rethinking isolated cleft lip and palate as a syndrome
Koruyucu, Mine; Kasımoğlu, Yelda; Seymen, Figen; Bayram, Merve; Patır Münevveroğlu, Aslı; Ergöz, Nihan; Tuna, Elif Bahar; Gencay, Koray; Deeley, Kathleen; Bussaneli, Diego; Modesto, Adriana; Vieira, Alexandre R. (Elsevier Science Inc, 2018)Objective. The goal of the present work was to use dental conditions that have been independently associated with cleft lip and palate (CL/P) as a tool to identify a broader collection of individuals to be used for gene ...
