Browsing by Author "Sever, Tolga"
Now showing items 1-3 of 3
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Carvacrol alters soluble factors in HCT-116 and HT-29 cell lines
Pakdemirli, Ahu; Karaca, Caner; Sever, Tolga; Daskın, Ezgi; Leblebici, Asım; Yiğitbaşı, Türkan; Başbınar, Yasemin (TUBITAK Scientific & Technical Research Council Turkey, 2020)Background/aim: Natural products are popular insights for researchers to investigate promising anti-cancer agents since some of these substances have lesser adverse effects restricting the treatment than traditional ... -
Curcumin effects on cell proliferation, angiogenesis and metastasis in colorectal cancer
Çalıbaşı-Kocal, Gizem; Pakdemirli, Ahu; Bayrak, Serdar; Özüpek, Nazlı Mert; Sever, Tolga; Başbınar, Yasemin; Ellidokuz, Hülya; Yiğitbaşı, Türkan (Zerbinis Publications, 2019)Purpose: Curcumin is a natural phytopolyphenol compound isolated from the root of turmeric (Curcuma longa) and possesses a wide range of biological properties. The purpose of this study was to evaluate the antiproliferative, ... -
Targeting the tumor metabolism by oxamate potentiates the impact of chemotherapeutics in colorectal cancer cells
Çalıbaşı Koçal, Gizem; Çakıcı, Çağrı; Toksöz, Feriha; İnanç Sürer, Seniz; Sever, Tolga; Başbınar, Yasemin; Yiğitbaşı, Türkan (Dokuz Eylül University Institute of Health Sciences, 2021)Purpose: Cancer cells promote lactate formation via pyruvate rather than oxidative phosphorylation by programming their metabolism to maintain proliferation under the Warburg effect. It has shown that the altered metabolic ...
