Browsing by Author "Saka, Burcu"
Now showing items 1-20 of 37
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Calculation of the Ki67 index in pancreatic neuroendocrine tumors: A comparative analysis of four counting methodologies
Reid, Michelle Dian; Bağcı, Pelin; Ohike, Nobuyuki; Saka, Burcu; Erbarut Seven, İpek; Dursun, Nevra; Balcı, Serdar; Gucer, Hasan; Jang, Kee-Taek; Tajiri, Takuma; Baştürk, Olca; Kong, So Yeon; Goodman, Michael; Akkaş, Gizem; Adsay, Volkan (Nature Publishing Group, 2015)Ki67 index is now an essential part of classification of pancreatic neuroendocrine tumors. However, its adaptation into daily practice has been fraught with challenges related to counting methodology. In this study, three ... -
Can the use of reference pictures improve the interobserver variability on assessment of liver steatosis percentage: A digital platform based approach
Türkmen Çetinaslan, İlknur; Çakır, Aslı; Çapar, Aslı Gizem; Saka, Burcu; Kahraman, Zuhal; Erkan, Sengiz; Özkan, Yücel; Kepil, Nuray; Keser, Sevinç Hallaç; Güçin, Zuhal; Ceyran, Bahar; Çoban, Ganime; Yılmaz Seğmen, Müberra; Arıcı, Sema; Dursun, Nevra; Doğusoy, Gülen Bülbül; Tuncel, Dilek; Özgüven Yılmaz, Banu; Paşaoğlu, Esra; Kamalı Harman, Gülçin; Kırımlıoğlu, Hale; Erdamar, Sibel; Yıldız, Şemsi; Erdoğan Yıldırım, Nilsen; Armutlu, Ayşe (Springer, 2017)… -
Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1 alpha, CXCR4 and CA9 in colorectal carcinoma
Saka, Burcu; Ekinci, Özgür; Dursun, Ayşe; Akyürek, Nalan (Elsevier Gmbh, 2017)Objective: To investigate the immunohistochemical expressions of HIF-1 alpha, CA9 and CXCR4 in resected human CRC specimens in relation to clinicopathologic and prognostic variables. Methods: A total of 186 patients (mean(SD) ... -
Comparison of CT methods for determining graft steatosis in living donor liver transplantation
Şeker, Mehmet; Erol, Cengiz; Sevmiş, Şinasi; Saka, Burcu; Durur-Karakaya, Afak (Springer, 2019)Purpose: To evaluate and compare the diagnostic performance of non-enhanced computed tomography (NECT) and contrast-enhanced CT (CECT) attenuation indices in the assessment of hepatic steatosis by using biopsy as the ... -
The contribution of additional sampling in cholecystectomy materials: A multicenter prospective study
Abdullazade, Samir; Akarca, Fahire Göknur; Esendağlı, Güldal; Turhan, Nesrin; Erden, Esra; Savaş, Berna; Markoç, Fatma; Tuncel, Deniz; Özgüven Yılmaz, Banu; Saka, Burcu; Hallaç Keser, Sevinç; Şengiz Erhan, Selma; Gücin, Zühal; Sağol, Özgül; Ağalar, Anıl Aysal; Çelik, Sevinç; Özer, Hatice; Erbarut Seven, İpek; Ataizi Çelikel, Çiğdem; Ekinci, Özgür; Eğilmez, Hatice Reyhan; Balcı, Serdar; Akyol, Gülen (Federation of Turkish Pathology Societies, 2020)Objective: Cholecystectomy materials arc frequently encountered in routine practice. The aim of this study was to determine the true frequency of gallbladder lesions, the diagnostic consistency, and standardization of ... -
The conversion ofRASstatus in metastatic colorectal cancer patients after first-line biological agent treatment
Arıcı, Serdar; Hamdard, Jamshid; Sakin, Abdullah; Şengiz Erhan, Selma; Atçı, Muhammed Mustafa; Cekin, Ruhper; Saka, Burcu; Köse, Emin; Saydam, Tuba; Geredeli, Çağlayan; Cihan, Şener; Bilici, Ahmet (Wiley, 2021)Aim The aim was to investigate theRASdiscordance between initial and recurrent metastasectomy specimens in metastatic colorectal cancer (mCRC) patients treated with chemotherapy (CT) plus biological agents in a first-line ... -
The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats
Özdenkaya, Yaşar; Ölmüşçelik, Oktay; Basım, Pelin; Saka, Burcu; Arslan, Naciye Çiğdem (Ociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2019)Purpose: To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods: Fourteen adult wistar rats 300 gr were randomized into two groups: Control group (n=7) and study group (n=7). All the ... -
Effects of whey Protein, Omega-3 Fatty Acid and Roux-En-Y gastric bypass on body weight, biochemical parameters and organ functions in an obese rat model: Experimental research
Mert Biberoğlu, Fatma; Erdem, Nihal Zekiye; Özdenkaya, Yaşar; Özdemir, Ekrem Musa; Saka, Burcu (Springer, 2023)Purpose: Extreme obesity (EO) is one of the biggest public health problems in the world and has grown considerably over the years. The aim of the study is to examine the effect of Roux-en-Y gastric bypass (RYGB), whey ... -
Epithelial inclusions in the gallbladder: cytoisospora belli organisms or degenerative intracytoplasmic pas-positive hyaline globules
Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Memiş, Bahar; Saka, Burcu; Bağcı, Pelin; Balcı, Serdar; Cheng, Jeanette; Baştürk, Olca; Reid, Michelle; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Lai et al. reported 18 cases of Cystoisospora belli in the gallbladders (GBs), detected incidentally in 0.5% ofimmunocompetent patients (PMID: 27158759). However, a recent molecular study failed to confirm this ... -
Epithelial inclusions in the gallbladder: cytoisospora belli organisms or degenerative intracytoplasmic pas-positive hyaline globules
Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Memiş, Bahar; Saka, Burcu; Bağcı, Pelin; Balcı, Serdar; Cheng, Jeanette; Baştürk, Olca; Reid, Michelle; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Lai et al. reported 18 cases of Cystoisospora belli in the gallbladders (GBs), detected incidentally in 0.5% ofimmunocompetent patients (PMID: 27158759). However, a recent molecular study failed to confirm this ... -
Field risk ("field-effect"/"field-defect") in the gallbladder and biliary tree: An under-recognized phenomenon with major implications for management and carcinogenesis
Reid, Michelle; Losada, Hector; Muraki, Takashi; Pehlivanoğlu, Burçin; Memiş, Bahar; Koshiol, Jill; Bağcı, Pelin; Seven, İpek Erbarut; Balcı, Serdar; Saka, Burcu; Dursun, Nevra; Jang, Keetaek; Ohike, Nobuyuki; Tajiri, Takuma; Goodman, Michael; Carlos Roa, Juan; Araya, Juan; Bellolio, Enrique; Sarmiento, Juan; Xue, Yue; Baştürk, Olca; Adsay, Volkan (Nature Publishing Group, 2019)... -
Field risk ("field-effect"/"field-defect") in the gallbladder and biliary tree: An under-recognized phenomenon with major implications for management and carcinogenesis
Reid, Michelle; Losada, Hector; Muraki, Takashi; Pehlivanoğlu, Burçin; Memiş, Bahar; Koshiol, Jill; Bağcı, Pelin; Seven, İpek Erbarut; Balcı, Serdar; Saka, Burcu; Dursun, Nevra; Jang, Keetaek; Ohike, Nobuyuki; Tajiri, Takuma; Goodman, Michael; Carlos Roa, Juan; Araya, Juan; Bellolio, Enrique; Sarmiento, Juan; Xue, Yue; Baştürk, Olca; Adsay, Volkan (Nature Publishing Group, 2019)... -
Follicular cholecystitis: Reappraisal of incidence, definition, and clinicopathologic associations in an analysis of 2550 cholecystectomies
Saka, Burcu; Memiş, Bahar; Erbarut Seven, İpek; Pehlivanoğlu, Burçin; Balcı, Serdar; Bağcı, Pelin; Reid, Michelle; Dursun, Nevra; Tapia Escalano, Oscar; Carlos Roa, Juan; Carlos Araya, Juan; Kong, So Yeon; Baştürk, Olca; Koshiol, Jill; Adsay, N. Volkan (SAGE Publications Inc, 2020)Context.Follicular cholecystitis (FC) is a poorly characterized entity.Objective.To determine its frequency/clinicopathologic associations.Design.A total of 2550 cholecystectomy specimens were examined. Two hundred three ... -
Gallbladder polyps: Correlation of size and clinicopathologic characteristics based on updated definitions
Taşkın, Orhun C.; Baştürk, Olca; Reid, Michelle D.; Dursun, Nevra; Bağcı, Pelin; Saka, Burcu; Balcı, Serdar; Memiş, Bahar; Bellolio, Enrique; Araya, Juan Carlos; Roa, Juan Carlos; Tapia, Oscar; Losada, Hector; Sarmiento, Juan; Jang, Kee-Taek; Jang, Jin-Young; Pehlivanoğlu, Burçin; Erkan, Mert; Adsay, Volkan (Public Library of Science, 2020)Background Different perspectives exist regarding the clinicopathologic characteristics, biology and management of gallbladder polyps. Size is often used as the surrogate evidence of polyp behavior and size of >= 1cm is ... -
Hepatocellular carcinomas with granulomatous inflammation in tumor stroma: Clinicopathologic characteristics
Saka, Burcu; Özden, Ferhat; Armutlu, Ayşe; Ertuğrul, Gökhan (Federation of Turkish Pathology Societies, 2022)Objective: To determine the frequency of granulomatous inflammation within hepatocellular carcinoma (HCC) and its clinicopathologic associations. Material and Method: Fifty-eight HCCs (51 explants, 3 lobectomies, and 4 ... -
Histopathologic infiltration pattern predicts metastasis and progression better than pT-stage and grade in well-differentiated pancreatic neuroendocrine tumors: A proposal for an infiltration-based morphologic grading system
Taşkın, Orhun; Reid, Michelle; Bağcı Çulçi, Pelin; Balcı, Serdar; Armutlu, Ayşe; Demirtaş, Deniz; Pehlivanoğlu, Burçin; Saka, Burcu; Memiş, Bahar; Bozkurtlar, Emine; Leblebici, Can Berk; Corobea, Adelina Birceanu; Xue, Yue; Erkan, Mert; Kapran, Yersu; Sökmensüer, Cenk; Scarpa, Aldo; Luchini, Claudio; Baştürk, Olca; Adsay, Nazmi Volkan (Springer Nature, 2021)... -
Histopathologic infiltration pattern predicts metastasis and progression better than pT-stage and grade in well-differentiated pancreatic neuroendocrine tumors: A proposal for an infiltration-based morphologic grading system
Taşkın, Orhun; Reid, Michelle; Bağcı Çulçi, Pelin; Balcı, Serdar; Armutlu, Ayşe; Demirtaş, Deniz; Pehlivanoğlu, Burçin; Saka, Burcu; Memiş, Bahar; Bozkurtlar, Emine; Leblebici, Can Berk; Corobea, Adelina Birceanu; Xue, Yue; Erkan, Mert; Kapran, Yersu; Sökmensüer, Cenk; Scarpa, Aldo; Luchini, Claudio; Baştürk, Olca; Adsay, Nazmi Volkan (Springer Nature, 2021)... -
Is it justifiable to move the grade-1 ki67 index cut-off from 3% to 5% for pancreatic neuroendocrine tumors as has been proposed? The cases that fall to 3-5% category have clinicopathologic characteristics closer to those > 5%
Reid, Michelle; Balcı, Serdar; Bağcı, Pelin; Saka, Burcu; Pehlivanoğlu, Burçin; Erbarut Seven, İpek; Baştürk, Olca; Adsay, N. Volkan (Nature Publishing Group, 2020)Background: Grading of linear parameters into meaningful (clinically relevant) clusters is a well-known challenge. Recently several groupshave proposed to change the Ki67 index cut-off for grade 1 (G1) category for PanNETs ...
