Browsing by Author "Patır, Aslı"
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8-12 yaş arası çocuklarda görülen kötü ağız alışkanlıklarının sıklığı
Yıldırım, Mine; Bayram, Merve; Patır, Aslı; Yalçın, Ferhan; Seymen, Figen (Istanbul University Press, 2011)Bu çalışmanın amacı, 8-12 yaşları arasındaki çocuklarda kötü ağız alışkanlıklarının sıklığının değerlendirilmesi ve sonuçlarının yaşa ve ağız sağlığına göre karşılaştırılmasıdır. Yaşları 8 ile 12 arasında değişen 107 çocuk ... -
Aquaporin 5 interacts with fluoride and possibly protects against caries
Anjomshoaa, Ida; Briseno-Ruiz, Jessica; Deeley, Kathleen; Poletta, Fernardo; Mereb, Juan; Leite, Aline; Barreta, Priscila; Silva, Thelma; Dizak, Piper; Ruff, Timothy; Patır, Aslı; Koruyucu, Mine; Abbasoğlu, Zerrin; Casado, Priscila; Brown, Andrew; Zaky, Samer; Bayram, Merve; Kuechler, Erika; Cooper, Margaret; Liu, Kai; Marazita, Mary; Tanboğa, İlknur; Granjeiro, Jose; Seymen, Figen; Castilla, Eduardo; Orioli, Ieda; Sfeir, Charles; Owyang, Hongjiao; Buzalaf, Marilia; Vieira, Alexandre (Public Library of Science, 2015)Aquaporins (AQP) are water channel proteins and the genes coding for AQP2, AQP5, and AQP6 are clustered in 12q13. Since AQP5 is expressed in serous acinar cells of salivary glands, we investigated its involvement in caries. ... -
Candidate gene studies in hypodontia suggest role for FGF3
Vieira, Alexandre Rezende; D'Souza, Rena; Mues, Gabriele; Deeley, Kathleen; Hsin, Hongyuan; Küchler, Erika Calvano; Meira, Raquel; Patır, Aslı; Tannure, Patrícia Nivoloni; Lips, Andrea; Meneghim, Marcelo de Castro; Granjeiro, José Mauro; Seymen, Figen; Modesto, Adriana (2013)Introduction The majority of tooth agenesis cases are mild (hypodontia) and typically not associated with the gene mutations linked to oligodontia. From this, we hypothesise that most cases of tooth agenesis fit a polygenic ... -
Enamel formation genes influence enamel microhardness before and after cariogenic challenge
Shimizu, Takehiko; Ho, Bao; Deeley, Kathleen; Briseno-Ruiz, Jessica; Faraco, Italo Medeiros; Schupack, Brett Ian; Brancher, Joäo Armando; Pecharki, Giovana Daniela; Küchler, Erika Calvano; Tannure, Patrícia Nivoloni; Lips, Andrea; Vieira, Thays Cristinedos Santos; Patır, Aslı; Yıldırım, Mine; Poletta, Fernando Adrián; Mereb, Juan Carlos; Resick, Judith M.; Brandon, Carla A.; Orioli, Ieda M.; Castilla, Eduardo Enrique; Marazita, Mary Louise; Seymen, Figen; Costa, Marcelo Costra; Granjeiro, José Mauro; Trevilatto, Paula Cristina; Vieira, Alexandre Rezende (Public Library Science, 2012)There is evidence for a genetic component in caries susceptibility, and studies in humans have suggested that variation in enamel formation genes may contribute to caries. For the present study, we used DNA samples collected ... -
Estetik restoratif materyallerin cila işlemlerinden sonra yüzey yapısının sem ile incelenmesi
Yıldırım, Mine; Patır, Aslı; Seymen, Figen; Gençay, Koray (Atatürk Üniversitesi, 2012)Amaç: Bu çalışmanın amacı, ışıkla polimerize olan iki farklı cam iyonomer materyali ile iki farklı posterior bölge kompozit materyalinin yüzey özelliklerini cila işlemleri uygulandıktan sonra analiz etmektir. Gereç-Yöntem: ... -
Fine mapping of locus Xq25.1-27-2 for a low caries experience phenotype
Küchler, Erika Calvano; Feng, Ping; Deeley, Kathleen; Fitzgerald, Carly A.; Meyer, Chelsea; Gorbunov, Anastasia; Bezamat, Mariana; Reis, Maria Fernanda; Noel, Jacqueline; Kouzbari, M. Zahir; Granjeiro, Jose Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Vieira, Alexandre Rezende (Pergamon-Elsevier Science Ltd., 2014)Objective: The purpose of this study was to fine map the locus Xq25.1-27-2 in order to identify genetic contributors involved in low caries experience. Design: Seventy-two families from the Philippines were studied. Caries ... -
Fine-Mapping of 5q12.1-13.3 unveils new genetic contributors to caries
Shimizu, Takehiko; Deeley, Kathleen; Briseno Ruiz, Jessica; Faraco, Italo Medeiros; Poletta, Fernando Adrian; Brancher, Joao Armando; Pecharki, Giovana Daniela; Kuechler, Erika Calvano; Tannure, Patricia Nivoloni; Lips, Andrea; Vieira, Thays Cristinedos Santos; Patır, Aslı; Yıldırım, Mine; Mereb, Juan Carlos; Resick, Judith; Brandon, Carla; Cooper, Margaret; Seymen, Figen; Costa, Marcelo de Castro; Granjeiro, Jose Mauro; Trevilatto, Paula Cristina; Orioli, Ieda Maria; Castilla, Eduardo Enrique; Marazita, Mary Louise; Vieira, Alexandre Rezende (Karger, 2013)Caries is a multifactorial disease and little is still known about the host genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified the interval 5q12.1-5q13.3 as linked to low caries ... -
Genetic mapping of high caries experience on human chromosome 13
Küchler, Erika Calvano; Deeley, Kathleen; Ho, Bao; Linkowski, Samantha; Meyer, Chelsea; Noel, Jacqueline; Kouzbari, M. Zahir; Bezamat, Mariana; Granjeiro, José Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Mereb, Juan Carlos; Poletta, Fernando Adrián; Castilla, Eduardo Enrique; Orioli, Iêda Maria; Marazita, Mary Louise; Vieira, Alexandre Rezende (BMC, 2013)Background: Our previous genome-wide linkage scan mapped five loci for caries experience. The purpose of this study was to fine map one of these loci, the locus 13q31.1, in order to identify genetic contributors to caries. ... -
Role of estrogen related receptor beta (ESRRB) in DFN35B hearing impairment and dental decay
Weber, Megan L.; Hsin, Hong-Yuan; Kalay, Ersan; Brozkova, Dana Safka; Shimizu, Takehiko; Bayram, Merve; Deeley, Kathleen; Kuchler, Erika Calvano; Forella, Jessalyn; Ruff, Timothy; Trombetta, Vanessa M.; Sencak, Regina C.; Hummel, Michael; Briseno-Ruiz, Jessica; Revu, Shankar; Granjeiro, Jose Mauro; Antunes, Leonardo Dos Santos; Alves Antunes, Livia Azeredo; Abreu, Fernanda; Costa, Marcelo Castro; Tannure, Patricia Nivoloni; Koruyucu, Mine; Patır, Aslı; Poletta, Fernando; Mereb, Juan C.; Castilla, Eduardo Enrique; Orioli, Leda M.; Marazita, Mary L.; Ouyang, Hongjiao; Jayaraman, Thottala; Seymen, Figen; Vieira, Alexandre Rezende (BMC, 2014)Background: Congenital forms of hearing impairment can be caused by mutations in the estrogen related receptor beta (ESRRB) gene. Our initial linkage studies suggested the ESRRB locus is linked to high caries experience ...