Browsing by Author "Omurtag, Gülden Zehra"
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Advers etki sebebiyle pazardan toplatılan ilaçlar
İkinci Çokay, Emine (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2020)Farmakovijilans, advers etkilerin veya ilaçla ilgili olası diğer sorunların tespiti, değerlendirilmesi, anlaşılması ve önlenmesi ile ilgili bilim ve faaliyetlerdir. Advers etki bir beşeri tıbbi ürünün hastalıktan korunma, ... -
Antihipertansif ilaç kullanan hastaların hasta eğitimi, uyuncu ve hasta takibinde klinik eczacının rolü
Göçmen, Ece (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2020)Yüksek kan basıncı olarak da adlandırılan hipertansiyon kan basıncının kronik olarak yüksek olduğu tıbbi durumdur. Hipertansiyon dünya çapında en önemli kardiyovasküler risk faktörlerinden biridir. Antihipertansif ilaçlar ... -
Antioksidan maddelerin mutajenite üzerine etkilerinin ames testi ile incelenmesi
Beceren, Ayfer; Sarıkaya, Betül; Tatlıpınar, Eşref; Omurtag, Gülden Zehra; Şardaş, Semra (Marmara Üniversitesi, 2017)Nowadays, several test systems have been developed in order to observe the mutagenic effects of chemical agents which play crucial roles in human health. The Ames Test is one of these test systems. With the Ames Test, some ... -
The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
Söylemez, Esra; Özçağlı, Eren; Korkmaz, Serol; Tok, Olgu Enis; Aydın, Mehmet Şerif; Omurtag, Gülden Zehra (SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Biological activities of the Ornithogalum orthophyllum and its in silico ADMET profile
Taşkın, Duygu; Şentürk, Şeyda; Güler, Eray Metin; Doğan, Ahmet; Omurtag, Gülden Zehra; Ermanoğlu, Mizgin; Taşkın, Turgut (TMR Publishing Group, 2021)Background: The bulbs and aerial parts of Ornithogalum are used in Turkey both as food and to treat various ailments, and some of its medical applications are well known. However, the biological activities of Ornithogalum ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
Omurtag Özgen, Pınar Sinem; Biltekin, Sevde Nur; İduğ, Tuğba; Macit, Çağlar; Ayran, İrem; Çelik, Sadiye Ayşe; Kültür, Şükran; Kan, Yüksel; Omurtag, Gülden Zehra (Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Comparison of inhaled and intraperitoneal formaldehyde toxicity in rats and the evaluation of the effects of melatonin
Aydemir, Sezgin; Akgün, Sevcan Gül; Topfedaisi Özkan, Nazlı; Yüksel, Meral; Beceren, Ayfer; Erdoğan, Nusret; Omurtag, Gülden Zehra (Elsevier Ireland Ltd, 2016)Formaldehyde (FA) is a genotoxic substance that causes deleterious effects on the nervous system, respiratory system, and reproductive system as a result of occupational exposure. FA is also classified as human carcinogen ... -
Çalışanlarda bireysel sağlığın yönetimi açısından bireysel iyilik halinin ve sağlık risklerinin değerlendirilmesi
Uyar, Metin (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2017)Bu araştırma çalışanlarda bireysel sağlığın yönetimi açısından bireysel iyilik halinin ve sağlık risklerinin değerlendirilmesi amacıyla yapılmıştır. Araştırma kapsamına İstanbul'da belirlenen şirketlerde çalışmakta olan ... -
D vitamini eksikliğinde görülen hastalıklar ve D vitamini eksikliğine etki eden faktörler ve bu hastalara farmasötik bakım sağlanmasında klinik eczacının rolü
Gürol, Cansu (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2019)D vitamini eksikliği özellikle yaşlılarda osteoporoz, çocuklarda raşitizme neden olmakla birlikte diyabetes mellitus, hipertansiyon, hiperkolesterolemi, astım, kronik obstrüktif akciğer hastalığı (KOAH), üst solunum yolları ... -
Diyabet ve kardiyovasküler hastalığı olan bireylerde reçete edilen ilaçlar arasındaki etkileşimin gözlenmesi
Kara Aksoy, Ülfet (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)İnsanlar yaşlandıkça kronik hastalık görülme olasılığı artmaktadır. Kronik hastalıklarla birlikte çoklu ilaç kullanımı da kaçınılmaz olmaktadır. Çoklu ilaç kullanımı kontrol edilmediği takdirde ilaç-ilaç etkileşimi ... -
DNA damage in gasoline station workers caused by occupational exposure to petrol vapour in Turkey
Beceren, Ayfer; Akdemir, Nebahat; Omurtag, Gülden Zehra; Tatlıpınar, Mücteba Eşref; Şardaş, Semra (University of Istanbul, 2016)The refueling of vehicles is a major source of volatile organic compounds generated by used and evaporated fuel. Gasoline workers are directly exposed to various fuel products via many routes in the ambient air. The aim ... -
The effect of carnitine against acrylamide-induced toxicity in rat lung and liver tissues
Aydemir, Sezgin; Güçlü, Hande; Özkan, Nazlı Topfedaisi; Yüksel, Meral; Erdoğan, Nusret; Omurtag, Gülden Zehra (Elsevier Ireland Ltd, 2016)Acrylamide (ACR) has the potential for cytotoxic and genotoxic effects by decreasing oxidative defense system and is known to be neurotoxic, hepatotoxic and carcinogenic to humans. Carnitine plays an important role in the ... -
Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward
Ceylan, Cengizhan; Sancar, Mesut; Beceren, Ayfer; Demir, Ali; Kuş, Coşkun; Omurtag, Gülden Zehra (Marmara University, 2022)Integrating clinical pharmacists in a multidisciplinary patient care team improves the treatment process by identifying and resolving drug-related problems (DRPs). The aim of the study was to determine the effect of clinical ... -
Evaluation of correlations between nutrients, fatty acids, heavy metals, and deoxynivalenol in corn (Zea mays L.)
Pekel, Ahmet Yavuz; Çalık, Ali; Alataş, Mustafa Selçuk; Kuter, Esen; Cengiz, Özcan; Omurtag, Gülden Zehra; İnan, Gül (Oxford University Press, 2019)This study was conducted to develop linear regression equations to estimate nutrients, fatty acids, heavy metals, color characteristics (L,* a,* b*), and deoxynivalenol (DON) level of corn grains (n = 54) collected from ... -
Evaluation of knowledge level about asbestos exposure in urban transformation construction areas
Konak, Özlem; Tatlıpınar, Mücteba Eşref; Omurtag, Gülden Zehra (University of Istanbul, 2017)Since Turkey is in an earthquake zone, historically there has been a lot of demolition in various cities, including Istanbul which contains many historical places. Residents of Istanbul are subject to calamity regulations ... -
Evaluation of the in vivo preclinical toxicity of targeted nanoparticles
Ceylan, Cengizhan; Tatlıpιnar, Mücteba Eşref; Tüccar, Sinem; Omurtag, Gülden Zehra; Akbuğa, Fatma Jülide (Taylor and Francis, 2021)Drug delivery systems include nanoparticles (NPs), nanoemulsions, nanosuspensions, nanoliposomes, niosomes, dendrimers, fullerene, carbon nanotubes, nanogels, polymeric micelles, and solid lipid NPs. Although the drug-based ... -
The influence of different extraction methods/solvents on composition, biological activities and ADMET predictions of phenolics in tribulus terrestris
Taşkın, Duygu; Yılmaz, Beyza Nur; Taşkın, Turgut; Omurtag, Gülden Zehra (Instituto de Tecnologia do Parana, 2021)Tribulus terrestris is a plant that has medical importance in treating diseases such as cancer, urinary tract infections, kidney stones, rheumatism, and hypertension. The aim of this study is to examine the effects of ... -
Investigation of antioxidant and anticonvulsant activity of Hypericum triquetrifolium Turra
Kırmızı Sönmez, Neriman İpek; Güler, Ece; Çam, Muhammet Emin; Ermanoğlu, Mizgin; Gürdal, Bahar; Taşkın, Turgut; Omurtag, Gülden Zehra (Marmara University, 2022)Epilepsy is a state characterized by sudden, recurrent epileptic seizures that are not initiated by an identifiable event. There are various studies has been shown that Hypericum species may be used for their anticonvulsant ... -
Investigation of genotoxicity risk and DNA repair capacity in breast cancer patients using anastrozole
Yeşil Devecioğlu, Tuğçe; Aydoğan, Fatih; Omurtag, Gülden Zehra; Şenel Bese, Nuran; Sardaş, Semra (Kare Publishing, 2018)OBJECTIVE: Breast cancer is the most common cancer in women worldwide and the incidence increases in postmenopausal women. Anastrozole is a non-steroidal (type II), third-generation aromatase inhibitor (AI) that is used ... -
Investigation of the deoxynivalenol and ochratoxin a levels by high-performance liquid chromatography of cereals sold in the markets in Türkiye
Şahin, Semih; Eyüpoğlu, Ozan Emre; Yaman, Mustafa; Çal Doğan, Tuğbagül; Omurtag Korkmaz, Burcu İrem; Omurtag, Gülden Zehra (Sociedade Brasileira de Ciencia e Tecnologia de Alimentos, SBCTA, 2023)The current research was conducted to determine the deoxynivalenol (DON) and ochratoxin A (OTA) levels of 24 pieces of wheat flour, 24 pieces of rice, 24 pieces of corn flour, and 24 pieces of whole wheat flour obtained ...
