Browsing by Author "Modesto, Adriana"
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Candidate gene studies in hypodontia suggest role for FGF3
Vieira, Alexandre Rezende; D'Souza, Rena; Mues, Gabriele; Deeley, Kathleen; Hsin, Hongyuan; Küchler, Erika Calvano; Meira, Raquel; Patır, Aslı; Tannure, Patrícia Nivoloni; Lips, Andrea; Meneghim, Marcelo de Castro; Granjeiro, José Mauro; Seymen, Figen; Modesto, Adriana (2013)Introduction The majority of tooth agenesis cases are mild (hypodontia) and typically not associated with the gene mutations linked to oligodontia. From this, we hypothesise that most cases of tooth agenesis fit a polygenic ... -
In vitro acid-mediated initial dental enamel loss is associated with genetic variants previously linked to caries experience
Vieira, Alexandre R.; Bayram, Merve; Seymen, Figen; Sencak, Regina C.; Lippert, Frank; Modesto, Adriana (Frontiers Media S.A., 2017)We have previously shown that AQP5 and BTF3 genetic variation and expression in whole saliva are associated with caries experience suggesting that these genes may have a functional role in protecting against caries. To ... -
Rethinking isolated cleft lip and palate as a syndrome
Koruyucu, Mine; Kasımoğlu, Yelda; Seymen, Figen; Bayram, Merve; Patır Münevveroğlu, Aslı; Ergöz, Nihan; Tuna, Elif Bahar; Gencay, Koray; Deeley, Kathleen; Bussaneli, Diego; Modesto, Adriana; Vieira, Alexandre R. (Elsevier Science Inc, 2018)Objective. The goal of the present work was to use dental conditions that have been independently associated with cleft lip and palate (CL/P) as a tool to identify a broader collection of individuals to be used for gene ...