Browsing by Author "Miski, Mahmut"
Now showing items 1-16 of 16
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Anatolicin, a highly potent and selective cytotoxic sesquiterpene coumarin from the root extract of heptaptera anatolica
Tosun, Fatma; Beutler, John A.; Ransom, Tanya; Miski, Mahmut (MDPI, 2019)Seven known sesquiterpene coumarins and a new sesquiterpene coumarin, anatolicin (8), were isolated from the dichloromethane extract of the roots of Heptaptera anatolica. Structures of these compounds were elucidated based ... -
Antimicrobial activity of the sesquiterpene esters of ferula halophila pesmen
Şahpaz, Sevser; Neut, Christel; Abedini, Amin; Miski, Mahmut (Georg Thieme Verlag Kg, 2013)… -
Biological activities and chemical constituents of ferula anatolica boiss
Kurtoğlu, Sezin; Tan, Nur Amanina Syariff; Meriçli, Ali Hikmet; Miski, Mahmut (Georg Thieme Verlag Kg, 2013)Genus Ferula has about 185 species and widely distributed through out Central Asia, China, Afghanistan, India, Syria, Palestine, Israel, North Africa, North America, South-West and Central Europe. Currently, 23 species and ... -
Biological activities of the essential oil, fruit and root extracts of ferula drudeana korovin
Miski, Mahmut; Kürkçüoğlu, Mine; İşcan, Gökalp; Göğer, Fatih; Tosun, Fatma (Georg Thieme Verlag Kg, 2013)… -
Biological activities of the fruit essential oil, fruit, and root extracts of ferula drudeana korovin, the putative anatolian ecotype of the silphion plant
Tosun, Fatma; Göger, Fatih; İşcan, Gökalp; Kürkçüoğlu, Mine; Kuran, Fadil Kaan; Miski, Mahmut (MDPI, 2023)In the present study, preliminary phytochemical investigations were performed on the fruit essential oil and antioxidant-rich methanolic extracts of the fruits and roots of Ferula drudeana, the putative Anatolian ecotype ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen
Kürkçüoğlu, Mine; İşcan, Gökalp; Tosun, Fatma; Miski, Mahmut (Istanbul Medipol University, 2023)The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
İşcan, Gökalp; Kürkçüoğlu, Mine; Tosun, Fatma; Miski, Mahmut (Istanbul Medipol University, 2023)The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were ... -
Biologically active sesquiterpenes from the indigenous ferula species (Apiaceae) of Turkey
Miski, Mahmut (Georg Thieme Verlag Kg, 2013)The genus Ferula comprises more than 180 species and is the largest genus of Apiaceae in Asia. There are 23 species of Ferula in Turkey and 17 of them are endemic. Ferula species are rich sources of sesquiterpenes with ... -
Butyrylcholinesterase-inhibiting natural coumarin molecules as potential leads
Erdoğan Orhan, İlkay; Tosun, Fatma; Şenol Deniz, Fatma Sezer; Eren, Gökçen; Mıhoğlugil, Feyyaz; Akalgan, Demet; Miski, Mahmut (Elsevier Ltd, 2021)Seventeen natural coumarin derivatives; badrakemin (1), 14′-acetoxybadrakemin (2), badrakemone (3), 14′-acetoxybadrakemone (4), colladonin (5), colladonin acetate (6), 14′-acetoxycolladonin (7), karatavicinol (8), deltoin ... -
Cytotoxic activity of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin
Tosun, Fatma; Miski, Mahmut (Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichlorometh-ane extract of the fruits of H. anatolica showed the ... -
Cytotoxic activity of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin
Tosun, Fatma; Miski, Mahmut (İstanbul Medipol University, 2020)Cytotoxic activities of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the roots of H. anisoptera showed ... -
Cytotoxic sesquiterpene coumarins from the roots of heptaptera cilicica
Tosun, Fatma; Aytar, Erdi Can; Beutler, John A.; Wilson, Jennifer A.; Miski, Mahmut (ACG Publications, 2021)Preliminary 2-day cancer cell screening assays indicated that the dichloromethane extract of the roots of Heptaptera cilicica showed relatively strong cytotoxic activity. Eleven sesquiterpene coumarin ethers with potent ... -
Neopapillarine, an unusual coumarino-alkaloid from the root extract of neocryptodiscus papillaris with cytotoxic activity on renal cancer cells
Tosun, Fatma; Mihoğlugil, Feyyaz; Beutler, John A. A.; Eroğlu Özkan, Esra; Miski, Mahmut (MDPI, 2020)Several simple and prenylated coumarin derivatives were isolated from the dichloromethane extract of the root of Neocryptodiscus papillaris based on moderate cytotoxic activity of the extract in COLO205, KM12 and MCF7 ... -
Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin
Tosun, Fatma; Miski, Mahmut (Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest ... -
Sesquiterpene coumarin ethers with selective cytotoxic activities from the roots of ferula huber-morathii Peşmen (Apiaceae) and unequivocal determination of the absolute stereochemistry of samarcandin
Eruçar, Fatma Memnune; Kuran, Fadıl Kaan; Altıparmak Ülbegi, Gülsüm; Özbey, Süheyla; Karavuş, Şule Nur; Arcan, Gülşah Gamze; Yazıcı Tütüniş, Seçil; Tan, Nur; Aksoy Sağırlı, Pınar; Miski, Mahmut (MDPI, 2023)Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some folkloric recipes used for cancer treatment also contain the resin of Ferula species. The dichloromethane extract of the roots of ...
