Browsing by Author "Metehan, İlter"

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Catalytically competent non-transforming H-RASG12P mutant provides insight into molecular switch function and GAP-independent GTPase activity of RAS

Metehan, İlter; Şensoy, Özge (Nature Publishing Group, 2019)

RAS mutants have been extensively studied as they are associated with development of cancer; however, H-RASG12P mutant has remained untouched since it does not lead to transformation in the cell. To the best of our knowledge, ...