Browsing by Author "Koruyucu, Mine"
Now showing items 1-16 of 16
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Alteration of exon definition causes amelogenesis imperfecta
Kim, Young-jae; Kang, Jenny; Seymen, Figen; Koruyucu, Mine; Zhang, Hong; Kasımoǧlu, Yelda; Bayram, Merve; Tuna-İnce, Elif Bahar; Bayrak, Şule; Tüloğlu, Nuray; Hu, Jan C.; Simmer, James P.; Kim, Jung-Wook (SAGE Publications Inc., 2020)Amelogenesis imperfecta (AI) is a collection of genetic disorders affecting the quality and/or quantity of tooth enamel. More than 20 genes are, so far, known to be responsible for this condition. In this study, we recruited ... -
Aquaporin 5 interacts with fluoride and possibly protects against caries
Anjomshoaa, Ida; Briseno-Ruiz, Jessica; Deeley, Kathleen; Poletta, Fernardo; Mereb, Juan; Leite, Aline; Barreta, Priscila; Silva, Thelma; Dizak, Piper; Ruff, Timothy; Patır, Aslı; Koruyucu, Mine; Abbasoğlu, Zerrin; Casado, Priscila; Brown, Andrew; Zaky, Samer; Bayram, Merve; Kuechler, Erika; Cooper, Margaret; Liu, Kai; Marazita, Mary; Tanboğa, İlknur; Granjeiro, Jose; Seymen, Figen; Castilla, Eduardo; Orioli, Ieda; Sfeir, Charles; Owyang, Hongjiao; Buzalaf, Marilia; Vieira, Alexandre (Public Library of Science, 2015)Aquaporins (AQP) are water channel proteins and the genes coding for AQP2, AQP5, and AQP6 are clustered in 12q13. Since AQP5 is expressed in serous acinar cells of salivary glands, we investigated its involvement in caries. ... -
Comparison of root canal length measurement methods in primary teeth
Koruyucu, Mine; Bayram, Merve; Kasımoǧlu, Yelda; Seymen, Figen (University Library System, University of Pittsburgh, 2018)Objectves: The purpose of this study was to evaluate the accuracy of conven5onal radiography, intraoral digital radi- ovisiography and electronic apex locator in determining the working length of root canals in primary ... -
Erken çocukluk döneminde travmatik diş yaralanmalarının, maloklüzyonların ve diş çürüğünün ağız sağlığı ile ilişkili yaşam kalitesi üzerine etkisi
Gürcan, Aliye Tuğçe; Koruyucu, Mine; Bayram, Merve; Seymen, Figen (Selcuk University, 2021)Amaç: Bu çalışmanın amacı, travmatik diş yaralanmalarının (TDY) ve diş çürüğünün okul öncesi çocukların Ağız Sağlığı ile İlişkili Yaşam Kalitesi (OHRQoL) üzerindeki etkisini değerlendirmektir. Gereç ve Yöntemler: Ağız ... -
Fine mapping of locus Xq25.1-27-2 for a low caries experience phenotype
Küchler, Erika Calvano; Feng, Ping; Deeley, Kathleen; Fitzgerald, Carly A.; Meyer, Chelsea; Gorbunov, Anastasia; Bezamat, Mariana; Reis, Maria Fernanda; Noel, Jacqueline; Kouzbari, M. Zahir; Granjeiro, Jose Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Vieira, Alexandre Rezende (Pergamon-Elsevier Science Ltd., 2014)Objective: The purpose of this study was to fine map the locus Xq25.1-27-2 in order to identify genetic contributors involved in low caries experience. Design: Seventy-two families from the Philippines were studied. Caries ... -
Gene-environment interaction in molar-incisor hypomineralization
Bezamat, Mariana; Souza, Juliana Feltrin de; Silva, Fernanda M.F.; Corrêa, Emilly G.; Fatturi, Aluhê Lopes; Brancher, Joäo Armando; Carvalho, Flávia M.; Cavallari, Tayla; Bertolazo, Laís; Machado-Souza, Cleber; Koruyucu, Mine; Bayram, Merve; Racic, Andrea; Harrison, Benjamin M.; Sweat, Yan Yan; Letra, Ariadne; Studen-Pavlovich, Deborah A.; Seymen, Figen; Amendt, Brad A.; Iani Werneck, Renata; Costa, Marcelo C.; Modesto, Adriana M.; Vieira, Alexandre Rezende (Public Library of Science, 2021)Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. ... -
Genetic mapping of high caries experience on human chromosome 13
Küchler, Erika Calvano; Deeley, Kathleen; Ho, Bao; Linkowski, Samantha; Meyer, Chelsea; Noel, Jacqueline; Kouzbari, M. Zahir; Bezamat, Mariana; Granjeiro, José Mauro; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves; Abreu, Fernanda Volpe De; Meneghim, Marcelo de Castro; Tannure, Patrícia Nivoloni; Seymen, Figen; Koruyucu, Mine; Patır, Aslı; Mereb, Juan Carlos; Poletta, Fernando Adrián; Castilla, Eduardo Enrique; Orioli, Iêda Maria; Marazita, Mary Louise; Vieira, Alexandre Rezende (BMC, 2013)Background: Our previous genome-wide linkage scan mapped five loci for caries experience. The purpose of this study was to fine map one of these loci, the locus 13q31.1, in order to identify genetic contributors to caries. ... -
Investigating the level of knowledge of the community about oral and dental health
Birant, Sinem; Koruyucu, Mine; Özcan, Hazal; İlisulu, Ceren; Kasımoğlu, Yelda; Üstün, Nilüfer; Kocaaydın, Simin; Bektaş, Dilara; Usta, Gülsevim; Akay Tekin, Cansu; Bekiroğlu, Nural; Seymen, Figen (Georg Thieme Verlag, 2021)Objectives This study aimed to determine the knowledge and approaches of the participants about oral and dental health. Materials and Methods This was a questionnaire-based cross-sectional survey. Participants' demographic ... -
Investigation of surface topography of different root-end filling materials: an in vitro study
Koruyucu, Mine; Özcan, Hazal; Bayram, Merve; Çankaya, Abdullah Burak; Keklikoǧlu, Nurullah; Seymen, Figen (University Library System, University of Pittsburgh, 2019)Aim: Although there are many materials that can be used for retrograde filling in surgical endodontics, none of them can be regarded as an ideal material yet. The purpose of this study was to compare the surface topography ... -
Mutations in RELT cause autosomal recessive amelogenesis imperfecta
Kim, Jung-Wook; Zhang, Hong; Seymen, Figen; Koruyucu, Mine; Hu, Yuanyuan; Kang, Jenny; Kim, Youn Ju; Ikeda, Atsushi; Kasımoğlu, Yelda; Bayram, Merve; Zhang, Chuhua; Kawasaki, Kazuhiko; Bartlett, John D.; Saunders, Thomas L.; Simmer, James P.; Hu, Jan C-C. (Wiley, 2019)Amelogenesis imperfecta (AI) is a collection of isolated (non-syndromic) inherited diseases affecting dental enamel formation or a clinical phenotype in syndromic conditions. We characterized three consanguineous AI families ... -
Orthodontic treatment needs of children: Comparison of three index
Koruyucu, Mine; İnce Tuna, Elif Bahar; Seymen, Figen; Münevveroğlu Patır, Aslı; Acar, Gözde (Istanbul University, 2014)Purpose: An orthodontic treatment need index is a form of occlusal index devised initially to prioritize the need for treatment and to categorize the malocclusion and identify patients based upon treatment need. The aim ... -
Rethinking isolated cleft lip and palate as a syndrome
Koruyucu, Mine; Kasımoğlu, Yelda; Seymen, Figen; Bayram, Merve; Patır Münevveroğlu, Aslı; Ergöz, Nihan; Tuna, Elif Bahar; Gencay, Koray; Deeley, Kathleen; Bussaneli, Diego; Modesto, Adriana; Vieira, Alexandre R. (Elsevier Science Inc, 2018)Objective. The goal of the present work was to use dental conditions that have been independently associated with cleft lip and palate (CL/P) as a tool to identify a broader collection of individuals to be used for gene ... -
Risk factors for early childhood caries (ECC) in 2-5 years old children
Münevveroğlu Patır, Aslı; Koruyucu, Mine; Seymen, Figen (Istanbul University, 2014)Purpose: The aim of this study was to determine the association of dietary habits and socioeconomic status for early childhood caries (ECC) among 2-5 years old children. Materials and Methods: A total of 200 children (aged ... -
Role of estrogen related receptor beta (ESRRB) in DFN35B hearing impairment and dental decay
Weber, Megan L.; Hsin, Hong-Yuan; Kalay, Ersan; Brozkova, Dana Safka; Shimizu, Takehiko; Bayram, Merve; Deeley, Kathleen; Kuchler, Erika Calvano; Forella, Jessalyn; Ruff, Timothy; Trombetta, Vanessa M.; Sencak, Regina C.; Hummel, Michael; Briseno-Ruiz, Jessica; Revu, Shankar; Granjeiro, Jose Mauro; Antunes, Leonardo Dos Santos; Alves Antunes, Livia Azeredo; Abreu, Fernanda; Costa, Marcelo Castro; Tannure, Patricia Nivoloni; Koruyucu, Mine; Patır, Aslı; Poletta, Fernando; Mereb, Juan C.; Castilla, Eduardo Enrique; Orioli, Leda M.; Marazita, Mary L.; Ouyang, Hongjiao; Jayaraman, Thottala; Seymen, Figen; Vieira, Alexandre Rezende (BMC, 2014)Background: Congenital forms of hearing impairment can be caused by mutations in the estrogen related receptor beta (ESRRB) gene. Our initial linkage studies suggested the ESRRB locus is linked to high caries experience ... -
Role of TRAV locus in low caries experience
Briseno-Ruiz, Jessica; Shimizu, Takehiko; Deeley, Kathleen; Dizak, Piper; Ruff, Timothy; Faraco, Italo; Poletta, Fernando; Brancher, Joao; Pecharki, Giovana; Kuechler, Erika; Tannure, Patricia; Lips, Andrea; Vieira, Thays; Patir, Asli; Koruyucu, Mine; Mereb, Juan; Resick, Judith; Brandon, Carla; Letra, Ariadne; Silva, Renato; Cooper, Margaret; Seymen, Figen; Costa, Marcelo; Granjeiro, Jose; Trevilatto, Paula; Orioli, Ieda; Castilla, Eduardo; Marazita, Mary; Vieira, Alexandre (Springer, 2013)Caries is the most common chronic, multifactorial disease in the world today; and little is still known about the genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified five loci ... -
Saliva profiles in children with congenital heart disease
Koruyucu, Mine; Batu, Şule; Bayram, Merve; Uslu, Ezel; Güven, Yegane; Seymen, Figen (Istanbul University Press, 2020)Purpose The low salivary pH and buffering capacity are caused by using heart failure medications. For this reason oral health should be supported in cardiac patients, it is necessary that they attend dental clinics for ...