Browsing by Author "Haskó, György"

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A(2A) adenosine receptors regulate multiple organ failure after hemorrhagic shock in mice

Keleştemur, Taha; Németh, Zoltán H.; Pacher, Pal; Antonioli, Luca; Haskó, György (Lippincott Williams and Wilkins, 2022)

Trauma hemorrhagic shock (T/HS) is a clinical condition that causes multiple organ failure that needs rapid intervention. Restricted oxygen at the cellular level causes inflammation and subsequent cell death. Adenosine ...
Adenosine metabolized from extracellular ATP ameliorates organ injury by triggering A2BR signaling

Keleştemur, Taha; Németh, Zoltán H.; Pacher, Pal; Beesley, Jennet; Robson, Simon C.; Eltzschig, Holger K.; Haskó, György (NLM (Medline), 2023)

BACKGROUND: Trauma and a subsequent hemorrhagic shock (T/HS) result in insufficient oxygen delivery to tissues and multiple organ failure. Extracellular adenosine, which is a product of the extracellular degradation of ...