Browsing by Author "Gemici, Aliihsan"
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Adult case series of extramedullary relapsing acute myeloid leukemia (AML) after allogeneic stem cell transplantation in whom a rapid response and a reasonably long remission could be achieved with gemtuzumab ozogamycin (GO)
Sevindik, Ömür Gökmen; Gemici, Aliihsan; Usta, Furkan Selim; Çakır, Aslı; Sadri, Sevil; Bekoz, Hüseyin; Sargın, Fatma Deniz (The American Society of Hematology, 2019)Gemtuzumab Ozogamycin (GO) is a drug conjugated monoclonal antibody which targets CD33 an antigen highly expressed on the surface of AML blasts. GO is approved for the treatment of both newly-diagnosed and relapsed AML. ... -
Charlson comorbidity index (CCI) in diffuse large B-cell lymphoma: A new approach in a multicenter study
Eren, Rafet; Serin, İstemi; Atak, Süheyla; Pirdal, Betül Zehra; Nizam, Nihan; Gemici, Aliihsan; Aydın, Demet; Demirel, Naciye; Doğan, Esma Evrim; Yokuş, Osman (Springer, 2023)Purpose: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of adult lymphomas. The incidence of DLBCL increases with age and has a fairly rapid fatal course without treatment. Patients often have difficulty ... -
Clinical characteristics and therapeutic outcomes of paroxysmal nocturnal hemoglobinuria patients in Turkey: A multicenter experience
Gören Şahin, Deniz; Akay, Olga Meltem; Keklik, Muzaffer; Okan, Vahap; Karakuş, Abdullah; Demir, Cengiz; Erkurt, Mehmet Ali; İlkkılıç, Kadir; Yıldırım, Rahşan; Akgün Çağlıyan, Gülsüm; Aksu, Salih; Doğu, Mehmet Hilmi; Dal, Mehmet Sinan; Karakuş, Volkan; Gemici, Aliihsan; Terzi, Hatice; Kelkitli, Engin; Şıvgın, Serdar; Ünal, Ali; Yılmaz, Mehmet; Ayyıldız, Orhan; Korkmaz, Serdal; Eser, Bülent; Altuntaş, Fevzi (Springer, 2021)The aim of this study is to collect paroxysmal nocturnal hemoglobinuria (PNH) patient data from hematology centers all over Turkey in order to identify clinical features and management of PNH patients. Patients with PNH ... -
Evaluation of neurological imaging after hematopoietic stem cell transplantation in adults
Sadri, Sevil; Polat, Burcu; Balık Aydın, Berrin; Koçar, Hakan; Gemici, Aliihsan; Beköz, Hüseyin Saffet; Sevindik, Ömür Gökmen; Sargın, Fatma Deniz (Yüzüncü Yıl University Faculty of Medicine, 2022)To investigate the risk factors for, and the incidence of, structural abnormalities in brain imaging among hematopoetic stem cell transplant (HSCT) patients and to correlate these findings with physical examinations. This ... -
Evaluation of pai-1 polymorphisms in central and peripheral thromboembolies
Arıcı Düz, Özge; Olmuşçelik, Oktay; Gemici, Aliihsan; Saatçi Sancaktepe, Özlem (Ondokuz Mayıs Üniversitesi, 2021)Thromboembolism is a clinical finding that occurs due to thrombus; formed in the vascular system and has various etiological factors. It can be classified as central and peripheral thromboembolism. Our objective in this ... -
High-dose intravenous immunoglobulin therapy for novel coronavirus disease 2019: A brief report of two cases
Erdoğan, Cem; Çiftçi, Bahadır; Kızılaslan, Deniz; Ekinci, Mürsel; İpteç, Gülşen; Gemici, Aliihsan; Karaaslan, Pelin (Springer, 2020)To the Editor,Novel coronavirus disease 2019 (2019-nCoV) is a global pandemic which threatens all over the world. Thefirst cases were seen in Wuhan, China, in December2019 (Guo et al. 2020; Chen et al. 2020). It has ... -
Otolog kök hücre transplantasyonunda Sitomegalovirüs (CMV) ve Hepatit B (HBV) reaktivasyonu: Tek merkez deneyimi
Gemici, Aliihsan; Beköz, Hüseyin Saffet; Sevindik, Ömür Gökmen; Sadri, Sevil; Serin, İstemi; Erol, Vedat Buğra; Sargın, Fatma Deniz; Kaynar, Leylagül (Lösemi Lenfoma Miyelom Derneği, 2022)Amaç: Sitomegalovirüs (CMV) reaktivasyonu allojenik hematopoetik kök hücre transplantasyo- nu sırasında sık görülür. Hepatit B reaktivasyonu (HBV), akut hepatit ve fulminan karaciğer yet- mezliği veya sadece HBV DNA düzeyinde ... -
Preliminary report of the academic CAR-T (ISIKOK-19) cell clinical trial in Turkey: Characterization of product and outcomes of clinical application
Erdoğan, Ebru; Yalçın, Koray; Hemşinlioğlu, Cansu; Sezgin, Aslıhan; Seyis, Utku; Kançağı, Derya Dilek; Taştan, Cihan; Yurtsever, Bulut; Turan, Raife Dilek; Çakırsoy, Didem; Abanuz, Selen; Sır Karakuş, Gözde; Elek, Muhammer; Beköz, Hüseyin Saffet; Gemici, Aliihsan; Sargın, Deniz; Arat, Mutlu; Ferhanoğlu, Burhan; Pekgüç, Ebru; Örnek, Serdar; Büyüktaş, Deram; Birgen, Nur; Ratip, Siret; Ovalı, Ercüment (Turkish Society of Hematology, 2022)Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products ... -
Prognostic factors and intensive care outcome in post-transplant phase of hematopoietic stem cell transplantation intensive care outcome in hematopoietic stem cell transplantation
Mutlu, Yaşa Gül; Balık Aydın, Berrin; Erdoğan, Cem; Kızılaslan, Deniz; Beköz, Hüseyin Saffet; Gemici, Aliihsan; Kaynar, Leylagül; Sevindik, Ömür Gökmen (Springer India, 2023)Introduction To identify new clinical and biologic parameters associated with short-term survival in allogeneic or autologous hematopoietic stem cell transplantation (HSCT) patients who were admitted to the intensive care ... -
Quality of life assessment with EORTC QLQ in patients with hodgkin lymphoma: Multicenter study
Gemici, Aliihsan; Serin, İstemi; Erol, Vedat Buğra; Doğu, Mehmet Hilmi; İnce, İdris; Eren, Rafet; Tekinalp, Atakan; Karakuş, Volkan; Sevindik, Ömür Gökmen (Ankara Hematology Oncology Association, 2022)Aim: The aim of our study is to obtain data on the quality of life (QoL) in Hodgkin lymphoma (HL) patients in a representative sample of the general population of Turkey with the help of the EORTC QLQ-C30 and QLQ-HL27 ... -
Quality of life assessment with EORTC QLQ in patients with multiple myeloma: Multicenter study
Gemici, Aliihsan; Serin, İstemi; Erol, Vedat Buğra; Doğu, Mehmet Hilmi; İnce, İdris; Eren, Rafet; Tekinalp, Atakan; Karakuş, Volkan; Koç Erol, İklil Nur; Arslan, Zeynep Ece; Tay, Zekiye Nur; Tuncer, Elif Nur; Sevindik, Ömür Gökmen (Galenos Publishing House, 2022)Objective: Both the length of the treatment period and the diversity of the agents used in the treatment significantly affect the quality of life (QoL) of the patients with multiple myeloma (MM). With the aid of the EORTC ... -
A real-life Turkish experience of venetoclax treatment in high-risk myelodysplastic syndrome and acute myeloid leukemia
Gemici, Aliihsan; Özkalemkaş, Fahir; Doğu, Mehmet Hilmi; Tekinalp, Atakan; Alacacıoğlu, İnci; Güney, Tekin; İnce, İdris; Gedük, Ayfer; Akgün Çağlıyan, Gülsüm; Maral, Senem; Serin, İstemi; Gündüz, Eren; Karakuş, Volkan; Beköz, Hüseyin Saffet; Eren, Rafet; Pınar, İbrahim Ethem; Güneş, Ahmet Kürşad; Sargın, Fatma Deniz; Sevindik, Ömür Gökmen (CIG Media Group, 2021)Venetoclax is a selective B-cell lymphoma 2 (BCL2) inhibitor, which is approved to treat elderly patients with newly diagnosed acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS). A total of 60 patients ... -
Rituximab-vemurafenib combination for the treatment of relapsed/Refractory hairy cell leukemia
Sevindik, Ömür; Gemici, Aliihsan; Mutlu, Yaşa Gül; Balık Aydın, Berrin; Çakır, Aslı (CIG Media Group, 2020)Objective: The management of R/R-HCL is not standardized yet. Patients with HCL universally harbor BRAF mutations, which makes BRAF inhibitors a potential treatment approach. The effi cacy and safety of the BRAF inhibitor ... -
A single center cohort of 40 severe COVID-19 patients who were treated with convalescent plasma
Gemici, Aliihsan; Bilgen, Hülya; Erdoğan, Cem; Kansu, Abdullah; Olmuşçelik, Oktay; Beköz, Hüseyin Saffet; Dinleyici, Rümeysa; Mert, Ali; Sevindik, Ömür Gökmen (Tübitak Scientific & Technical Research Council Turkey, 2020)Background/aim: A SARS-Cov2 infection which was first arised from Wuhan in December 2019 and named as COVID-19. Still there lacks either a specific treatment or a vaccine to treat COVID-19. Convalescent plasma (CP) was ... -
Survival outcomes of hypomethylating agents maintenance therapy in new diagnosed AML patients: Real experience data
Karakuş, Volkan; Maral, Senem; Kaya, Egemen; Gemici, Aliihsan; Dere, Yelda; Sevindik, Ömür Gökmen (Kare Publishing, 2022)OBJECTIVE: Acute myeloid leukemia (AML) is a hematological malignancy that frequently affects elderly population. With introducing the hypomethylating agents (HMAs) in elderly AML treatment, survival rates and quality of ...