Browsing by Author "Ganjalikhani Hakemi, Mazdak"

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An in silico investigation on the binding site preference of PD-1 and PD-L1 for designing antibodies for targeted cancer therapy

Abdolmaleki, Sarah; Ganjalikhani Hakemi, Mazdak; Ganjalikhany, Mohamad Reza (2024)

Cancer control and treatment remain a significant challenge in cancer therapy and recently immune checkpoints has considered as a novel treatment strategy to develop anti-cancer drugs. Many cancer types use the immune ...
Morphology-dependent immunomodulatory coating of hydroxyapatite/PEO for magnesium-based bone implants

Farshid, Safoura; Kharaziha, Mahshid; Salehi, Hossein; Ganjalikhani Hakemi, Mazdak (2023)

One of the most critical issues concerning orthopedic implants is the risk of chronic inflammation, which poses a threat to the bone healing process. Osteo-immunomodulation plays a pivotal role in implant technology by ...
Potential diagnostic value of abnormal pyroptosis genes expression in myelodysplastic syndromes (MDS): A primary observational cohort study

Soltani, Mohammad; Sharifi, Mohammad Jafar; Khalilian, Parvin; Sharifi, Mehran; Nematollahi, Pardis; Shapourian, Hooriyeh; Ganjalikhani Hakemi, Mazdak (2024)

Background: Myelodysplastic syndromes (MDS) are determined by ineffective hematopoiesis and bone marrow cytological dysplasia with somatic gene mutations and chromosomal abnormalities. Accumulating evidence has revealed ...