Browsing by Author "Güzel, Mustafa"
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Correction: The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20 (Oncogene, (2019), 38, 4, (469-482), 10.1038/s41388-018-0472-0)
Lee, Eunmi; Ouzounova, Maria D.; Piranlıoğlu, Raziye; Ma, Minh Thu; Güzel, Mustafa; Marasco, Daniela; Chadli, Ahmed; Gestwicki, Jason E.; Cowell, John K.; Wicha, Max S.; Hassan, Khaled A.; Korkaya, Hasan (Nature Publishing Group, 2019)Following publication of this article the authors noted that the Acknowledgments section had been omitted. This section should read as follows. -
Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents
Giray, Betül; Karadağ, Ayşe Esra; Şavluğ İpek, Özgecan; Pekel, Hanife; Güzel, Mustafa; Başpınar Küçük, Hatice (Elsevier, 2020)In drug-resistant phytopathogenic fungi, there has been extensive research on microbiological and antifungal drug development. In this study, a novel series of cylopentapyrazole bearing a 1,2,3-thiadiazole ring 2a-e were ... -
Essential parameters and risk factors of the patients for diabetes care and treatment
Bener, Abdulbari; Keskin, Fatma Ela; Kurtuluş, Eda Merve; Güzel, Mustafa; Çekirdekçi, Elif İjlal; Kadıoğlu, Pınar; Konukoğlu, Dildar; Öztürk, Mustafa (Elsevier Ltd, 2017)Aim: The aim was to explore the association between Type 2 Diabetes Mellitus [T2DM] treatment satisfactions of patients regarding their socio-economic, life-style, history medication and clinical outcome in a Turkish ... -
Ghrelin o-açil transferaz inhibisyonunun obezite üzerine etkisinin araştırılması
Burul, Şerife Betül (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2019)Obezite, hiperlipidemi, Tip-2 DM, hipertansiyon ve koroner kalp hastalıklarına sebep olan kronik bir hastalıktır ve son yıllarda dünyada ve ülkemizde hasta sayısı hızlı bir şekilde artmaktadır. Obezite, beraberinde ekonomik ... -
Identification and in vitro bioactivity screening of some marine-derived fungi from Turkish coastlines
Heydari, Hajar; Konuklugil, Belma; Giray, Betül; Karadağ, Ayşe Esra; Güzel, Mustafa (Cahiers de Biologie Marine, 2020)The marine environment represents a great variety of conditions of pressure, temperature, salinity, and light depending on depth, latitude and interactions with the continental shelf. These extreme and variable conditions ... -
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
Keskin, Elif; Üçışık, Mehmet Hikmet; Sucu, Bilgesu Onur; Güzel, Mustafa (MDPI, 2019)Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ... -
Özgün metil jasmonat mimetiklerinin hücre canlılığı üzerine etkinliklerinin insan akciğer ve yumurtalık kanser hatlarında incelenmesi
Yazıcı, Büşra Emine (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)Kanser dünyada olduğu gibi ülkemizde de yaygın hastalıkların başında gelmektedir. Warburg hipotezine göre, kanser hücrelerinin enerji tüketimi normal hücrelerden farklıdır. Kanser hücreleri normal hücrelerden farklı olarak ... -
The pleiotropic effects of TNF alpha in breast cancer subtypes is regulated by TNFAIP3/A20 (vol 38, pg 469, 2018)
Lee, Eunmi; Ouzounova, Maria; Piranlıoğlu, Raziye; Ma, Minh Thu; Güzel, Mustafa; Marasco, Daniela; Chadli, Ahmed; Gestwicki, Jason E.; Cowell, John Kenneth; Wicha, Max S.; Hassan, Khaled A.; Korkaya, Hasan (Nature Publishing Group, 2019)Following publication of this article the authors noted that the Acknowledgments section had been omitted. This section should read as follows. -
The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
Lee, Eunmi; Ouzounova, Maria; Piranlıoğlu, Raziye; Ma, Minh Thu; Güzel, Mustafa; Marasco, Daniela; Chadli, Ahmed; Gestwicki, Jason E.; Cowell, John Kenneth; Wicha, Max S.; Hassan, Khaled A.; Korkaya, Hasan (Nature Publishing Group, 2019)TNF alpha is a pleiotropic cytokine which fuels tumor cell growth, invasion, and metastasis in some malignancies, while in others it induces cytotoxic cell death. However, the molecular mechanism by which TNF alpha exerts ... -
Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model
Piranlıoğlu, Raziye; Lee, EunMi; Ouzounova, Maria; Bollag, Roni J.; Vinyard, Alicia H.; Arbab, Ali S.; Marasco, Daniela; Güzel, Mustafa; Cowell, John Kenneth; Thangaraju, Muthushamy; Chadli, Ahmed; Hassan, Khaled A.; Wicha, Max S.; Celis, Esteban; Körkaya, Hasan (Nature Publishing Group, 2019)Although clinically apparent metastasis is associated with late stages of cancer development, micro-metastatic dissemination may be an early event. However, the fate of these early disseminated tumor cells (DTC) remains ... -
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
Onur Sucu, Bilgesu; Savluğ İpek, Özgecan; Özdatlı Kurtuluş, Şükran; Yazıcı, Büşra Emine; Karakaş, Nihal; Güzel, Mustafa (Academic Press Inc Elsevier Science, 2019)Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in ... -
Synthesis of substituted pyridines from 1,2-nucleophilic addition products of functionalized N-acy1-2,3-dihydropyridones
Güzel, Mustafa; Watts, Joshua; McGilvary, Matthew; Wright, Marcus; Kiren, Sezgin (Pergamon-Elsevier Science, 2015)We describe herein a general and efficient synthetic approach toward substituted pyridines from functionalized N-acy1-2,3-dihydropyridones in two steps; 1,2-addition with organocerium reagents and subsequent oxidative ...
