Browsing by Author "Gök, Özlem"
Now showing items 1-9 of 9
-
ABCG5 and ABCG8 gene polymorphisms in type 2 diabetes mellitus in the Turkish population
Gök, Özlem; Ermiş Karaali, Zeynep; Acar, Leyla; Kılıç, Ülkan; Ergen, Arzu (Elsevier, 2015)Objective: The aim of the present study was to investigate the relationship between ABCG5 and ABCG8 gene polymorphisms and plasma lipid concentrations in Turkish patients with type 2 diabetes mellitus. Methods: Included ... -
Altered expression of micro-RNA 199a and increased levels of cardiac SIRT1 protein are associated with the occurrence of atrial fibrillation after coronary artery bypass graft surgery
Yamaç, Aylin Hatice; Küçükbuzcu, Sıtkı; Ozansoy, Mehmet; Gök, Özlem; Öz, Kürşat; Ertürk, Mehmet; Yılmaz, Emre; Ersoy, Burak; Zeybek, Rahmi; Göktekin, Ömer; Kılıç, Ülkan (Elsevier Science Inc, 2016)Background: Postoperative atrial fibrillation (POAF) is a potentially life-threatening complication after coronary artery bypass graft (CABG) surgery. The expression of the cardioprotective SIRT1 protein with its antioxidant ... -
Effects of foeniculum vulgare essential oil compounds, fenchone and limonene, on experimental wound healing
Keskin, İlknur; Günal, Mehmet Yalçın; Ayla, Şule; Kolbaşı, Bircan; Sayın Şakul, Arzu Ayşe; Kılıç, Ülkan; Gök, Özlem; Köroğlu, Kutay M.; Özbek, Hanefi (Taylor and Francis Ltd, 2017)We investigated the wound healing efficacy of the Foeniculum vulgare compounds, fenchone and limonene, using an excisional cutaneous wound model in rats. An excision wound was made on the back of the rat and fenchone and ... -
Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease
Gangarapu, Venkatanarayana; Tüzün İnce, Ali; Baysal, Birol; Kayar, Yusuf; Kılıç, Ülkan; Gök, Özlem; Uysal, Ömer; Şentürk, Hakan (Lippincott Williams and Wilkins, 2015)ObjectiveRecent studies have suggested that endotoxin-induced cytokines play an important role in nonalcoholic fatty liver disease (NAFLD). Rifaximin is a nonabsorbable antibiotic that might act on Gram-negative bacteria, ... -
Efficacy of statins on sirtuin 1 and endothelial nitric oxide synthase expression: The role of sirtuin 1 gene variants in human coronary atherosclerosis
Kılıç, Ülkan; Gök, Özlem; Elibol, Birsen; Uysal, Ömer; Bacaksız, Ahmet (Wiley, 2015)Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and are used to reduce the risk of coronary artery disease (CAD) due to their pleiotropic effects. Recently, greater focus has been placed on the role ... -
GAS6 intron 8 c.834+7G > A gene polymorphism in diabetic nephropathy
Erkoç, Reha; Çıkrıkçıoğlu, Mehmet Ali; Aintab, Emre; Erek-Toprak, Aybala; Kılıç, Ülkan; Gök, Özlem; Yasin Çetin, Ayşe İrem; Zorlu, Mehmet; Kıskaç, Muharrem; Çakırca, Mustafa; Erkal, Sena Nur; İsen, Hayati Can; Karatoprak, Cumali (Taylor and Francis, 2015)Background - Aim: In animal experiments, growth arrest-specific 6 (Gas6) protein plays a key role in the development of mesangial cell and glomerular hypertrophy in the early phase of diabetic nephropathy, and diabetic ... -
A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human
Kılıç, Ülkan; Gök, Özlem; Erenberk, Ufuk; Dündaröz, Mehmet Ruşen; Torun, Emel; Küçükardalı, Yaşar; Elibol, Birsen; Uysal, Ömer; Dündar, Tolga Turan (Public Library of Science, 2015)Aging is defined as the accumulation of progressive organ dysfunction. Controlling the rate of aging by clarifying the complex pathways has a significant clinical importance. Nowadays, sirtuins have become famous molecules ... -
SIRT1 gene variants are related to risk of childhood obesity
Kılıç, Ülkan; Gök, Özlem; Elibol, Birsen; Özgen, İlker Tolga; Erenberk, Ufuk; Uysal, Ömer; Dündaröz, Mehmet Ruşen (Springer, 2015)Obesity is a multifactorial disorder resulting from the interaction between genetic, psychological, physical, environmental, and socioeconomic factors. SIRT1 gene has important effects on the regulation of adiponectin, ...
