Browsing by Author "Erim, Ümit Can"
Now showing items 1-9 of 9
-
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
Arpa, Muhammet Davut; Seçen, İkbal Merve; Erim, Ümit Can; Hoş, Ayşegül; Üstündağ Okur, Neslihan (Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
Aydeğer, Asel; Ayşit, Neşe; Baydaş, Gülsena; Çakıcı, Çağrı; Erim, Ümit Can; Arpa, Muhammet Davut; Özçiçek, İlyas (Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
Development and evaluation of azelaic acid-cyclodextrin hydrogels for treatment of acne
Arpa, Muhammet Davut; Doğan, Nilay; Gündüz, Melisa; Karavelioğlu, Elçin Su; Erim, Ümit Can (Marmara University, 2024)Acne is an inflammatory or non-inflammatory disease that can be seen at every stage of human life and affects daily life both physically and psychologically. In the topical treatment of acne, substances with different ... -
Development of BDNF/NGF/IKVAV peptide modified and gold nanoparticle conductive PCL/PLGA nerve guidance conduit for regeneration of the rat spinal cord injury
Özçiçek, İlyas; Ayşit, Neşe; Balçıkanlı, Zeynep; Ulaş Aytürk, Nilüfer; Aydeğer, Asel; Baydaş, Gülsena; Aydın, Mehmet Şerif; Altıntaş, Esra; Erim, Ümit Can (2024)Spinal cord injuries are very common worldwide, leading to permanent nerve function loss with devastating effects in the affected patients. The challenges and inadequate results in the current clinical treatments are leading ... -
The effects of gold nanoparticles with different surface coatings and sizes on biochemical parameters in mice
Özçiçek, İlyas; Çakıcı, Çağrı; Ayşit, Neşe; Erim, Ümit Can (Prusa Medical Publishing, 2023)Objectives: Gold nanoparticles are very popular metallic nanomaterials and they have a wide spectrum of biomedical applications. This study was aimed to the production of stable and monodisperse polyethyleneimine (PEI) and ... -
The effects of various surface coatings of gold nanorods on toxicity, neuronal localization, microstructural alterations, and in vitro/in vivo biodistribution
Özçiçek, İlyas; Ayşit, Neşe; Çakıcı, Çağrı; Ulaş Aytürk, Nilüfer; Aydeğer, Asel; Erim, Ümit Can (Wiley, 2022)With the development of gold nanorods (AuNRs) for a number of biomedical applications, understanding their various biological effects has become important. Surface functionalization of AuNRs is attracting increasing attention ... -
Formulation, characterization and in vitro release studies of terbinafine hydrochloride loaded buccal films
Arpa, Muhammet Davut; Ünükür, Melike Zeynep; Erim, Ümit Can (Marmara University, 2021)Buccal administration of different active ingredients as an alternative to oral or dermal routes has been widely studied. The films are one of the most investigated dosage forms regarding the buccal formulations developed ... -
Identifying probiotic characteristics of lactobacillus crispatus isolated from the vagina
Er, Sevda; Erim, Ümit Can; Koç, Fatma; Kıvanç, Merih (University of São Paulo, 2019)Lactobacilli prevent overproduction of pathogenic microorganisms and contribute protecting vaginal microbiota. Many probiotic microorganisms are categorized as Lactic Acid Bacteria. In this study, it was aimed identifying ... -
Separation of gold(III) ions by 1,8-diaminonaphthalene-formaldehyde chelating polymer
Erim, Ümit Can; Gülfen, Mustafa; Aydın, Ali Osman (Elsevier Science Bv, 2013)In the present work, a new 1,8-diaminonaphthalene-formaldehyde (1,8-DAN-F) polymer was synthesized by the reaction of 1,8-DAN with formaldehyde solution. The structure of 1,8-DAN-F polymer was characterized by elemental ...
