Browsing by Author "Elmacı, İlhan"
Now showing items 1-16 of 16
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Caprylic acid ameliorates rotenone induced inflammation and oxidative stress in the gut-brain axis in Zebrafish
Cansız, Derya; Ünal, İsmail; Üstündağ, Ünsal Veli; Alturfan, Ahmet Ata; Altınöz, Meriç A.; Elmacı, İlhan; Emekli Alturfan, Ebru (Springer, 2021)Background Dysfunction of the gastrointestinal tract (GIT) is one of the most common non-motor symptom of Parkinson's Disease (PD). Pathological processes causing PD were suggested to initiate in the enteric nervous system ... -
Correlation between SPARC (Osteonectin) expression with immunophenotypical and invasion characteristics of pituitary adenomas
Onoz, Mustafa; Başaran, Recep; Güçlüer, Berrin; Işık, Nejat; Kaner, Tuncay; Sav, Aydın; Elmacı, İlhan (Blackwell Munksgaard, 2015)Pituitary adenomas are the third most common intracranial tumors. Invasive adenomas account for only 0.1-0.2% of pituitary tumors. SPARC is a matrix glycoprotein that plays a role in progression and invasiveness of neoplasms. ... -
Desmoplastic infantile ganglioglioma: Report of an unusual case with a cranial defect
Başaran, Recep; Çakır, Fatma Betül; Işık, Nejat; Sav, Aydın Murat; Elmacı, İlhan (Medknow Publications, 2014)Desmoplastic infantile ganglioglioma (DIG) is a rare tumor that typically occurs in infants under the age of 24 months. These tumors commonly have a good prognosis after surgical resection despite their aggressive radiological ... -
Diagnosis and management of the congenital cranial teratomas: Report of four cases and review
Işık, Nejat; Silav, Gökalp; Güçlüer, Berrin; Elmacı, İlhan (Journal of the Neurological Sciences, 2012)Konjenital intrakraniyal teratomlar iyi bilinen ancak ancak nadir görülen bir patolojidir, ve genellikle normal intrakraniyal yapının tam kaybı ile karakterizedirler. Her üç germ yaprağından da dokular içerirler. Bu yazıda ... -
Evaluation of the association between matrix metalloproteinase 11 and intervertebral disc disease
Aras, Adem Bozkurt; Güven, Mustafa; Balak, Naci; Ayan, Erdoğan; Uyar Bozkurt, Suheyla; Elmacı, İlhan (Turkish Neurosurgical Society, 2016)AIM: The intervertebral disc starts to degenerate when a human being begins to stand and learn to walk. It is known that many extrinsic, intrinsic and genetic factors play a role in disc degeneration. In this study, we ... -
The expression of MMP-11 in benign meningiomas
Ayan, Erdoǧan; Uyar, Süheyla Bozkurt; Çerçi, Ajlan; Altaş, Murat; Bölükbaşı, Fatih Han; Elmacı, İlhan; Sav, Aydın Murat (Journal Neurological Sciences, 2014)The WHO categorises tumours based on their histological properties; however, this classification falls short of understanding their biological behaviours. Recently, there has been an increase in the number of studies on ... -
Focal megalencephaly: Intraoperative ultrasound imaging in epilepsy surgery
Başkan, Özdil; Sılav, Gökalp; Demirci, Sema; Canöz, Özlem; Turanlı, Güzide; Elmacı, İlhan (Springer-Verlag, 2015)Hemimegalencephaly is a rare neuronal migration disorder that can be defined as abnormal neural and glial proliferation localized to all or part of a cerebral hemisphere. Most patients demonstrate intractable epilepsy, ... -
Methylnitrosourea, dimethylbenzanthracene and benzoapyrene differentially affect redox pathways, apoptosis and immunity in zebrafish
Eğimezer, G.; Üstündağ, Ünsal Veli; Ateş, Perihan Seda; Ünal, İsmail; Üstündağ, F. D.; Alturfan, Ahmet Ata; Emekli-Alturfan, Ebru; Adil Altınöz, Meriç; Elmacı, İlhan (SAGE Publications Ltd, 2020)Cancer continues to be a major cause of mortality globally. Zebrafish present suitable models for studying the mechanisms of genotoxic carcinogens. The aim of this study was to investigate the interaction between ... -
Microsurgical fenestration and cystoperitoneal shunt through preauricular subtemporal keyhole craniotomy for the treatment of symptomatic middle fossa arachnoid cysts in children
Sılav, Gökalp; Sarı, Ramazan; Bölükbaşı, Fatih Han; Altaş, Murat; Işık, Nejat; Elmacı, İlhan (Springer Verlag, 2015)The optimal surgical treatment for symptomatic middle fossa arachnoid cyst is still controversial. The most leading therapeutic options include cyst shunting and fenestration (endoscopic, microsurgical). We present our ... -
Neuroprotective effects of mitoquinone and oleandrin on Parkinson’s disease model in zebrafish
Ünal, İsmail; Çalışkan Ak, Esin; Üstündağ, Ünsal Veli; Ateş, Perihan Seda; Alturfan, Ahmet Ata; Altınöz, Meriç Adil; Elmacı, İlhan; Emekli Alturfan, Ebru (Taylor and Francis Ltd, 2020)Aim: The aim of this study is to investigate the possible protective effects of mitoquinone and oleandrin on rotenone induced Parkinson’s disease in zebrafish. Materials and methods: Adult zebrafish were exposed to rotenone ... -
A new molecule in aneurysmal subarachnoid hemorrhage: Dendroaspis natriuretic peptide
Şerefhan, Alpay; Altas, Murat; Çerçi, Ajlan; Işık, Nejat; Elmacı, İlhan (Turkish Neurosurgical Society, 2014)AIM: Dendroaspis natriuretic peptide (DNP) is the most recently identified member of the natriuretic peptide family. Although DNP has similar structure and function to other members, it is genetically different. The other ... -
Relation of apparent diffusion coefficient with Ki-67 proliferation index in meningiomas
Başkan, Özdil; Silav, Gökalp; Bölükbaşı, Fatih Han; Canöz, Özlem; Geyik, Serdar; Elmacı, İlhan (British Inst Radiology, 2016)Objective: The purpose of this study was to investigate the relationship between Ki-67 proliferation indexes and apparent diffusion coefficient (ADC) values of low-grade and atypical/anaplastic (high-grade) meningiomas. ... -
Relationship of intraoperative ultrasound characteristics with pathological grades and Ki-67 proliferation index in intracranial gliomas
Başkan, Özdil; Sılav, Gökalp; Sarı, Ramazan; Canöz, Özlem; Elmacı, İlhan (Springer Japan, 2015)The purpose of the present study was to investigate the relationship between the intraoperative ultrasonographic appearances and the histopathological characteristics of glial tumors using the pathological grading system ... -
The role of a single nucleotide polymorphism of the matrix metalloproteinase-1 gene promoter region in invasion and prognosis of meningiomas
Efendioğlu, Mustafa; Başaran, Recep; Bayrak, Ömer Faruk; Işık, Nejat; Kaner, Tuncay; Şahin, Fikrettin; Güçlü, Bülent; Elmacı, İlhan (Turkish Neurosurgical Society, 2014)AIM:The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region ... -
A simple technique for bone storage after decompressive craniectomy in children
Sılav, Gökalp; Bölükbaşı, Fatih Han; Özek, Erdinç; Tönge, Mehmet; Onoz, Mustafa; Elmacı, İlhan (Karger, 2014)Cranial vault reconstruction in the pediatric population is a specialized procedure, which requires additional considerations. Generally, inherent difficulties of bone storage and cranioplasty are neglected in the literature. ... -
Spinal arteriovenous malformation: Use of intraoperative color Doppler ultrasonography guidance for surgical resection. Case report
Başkan, Özdil; Durdağ, Emre; Geyik, Serdar; Elmacı, İlhan (Societatea Romana de Ultrasonografie in Medicina si Biologie-Srumb, 2014)Spinal arteriovenous malformations (AVMs) may be associated with sensory and motor deficits, bowel or bladder dysfunction, radicular pain or deficit, and back pain. Hemorrhage can occur in the parenchyma leading to the ...