Browsing by Author "Doğan, Mustafa"
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Are the leading drugs against Staphylococcus aureus really toxic to cartilage?
Doğan, Mustafa; İşyar, Mehmet; Yılmaz, İbrahim; Bilir, Bülent; Şirin, Duygu Y.; Çakmak, Selami; Mahiroğulları, Mahir (Elsevier Ltd, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Colistin nephrotoxicity increases with age
Balkan, İlker İnanç; Doğan, Mustafa; Durdu, Bülent; Batırel, Ayşe; Hakyemez, İsmail Necati; Çetin, Birsen; Karabay, Oğuz; Gönen, İbak; Özkan, Ahmet Selim; Uzun, Sami; Demirkol, Muhammed Emin; Akbaş, Sedat; Kaçmaz, Asiye Bahar; Aras, Sükrü; Mert, Ali; Tabak, Fehmi (Informa Healthcare, 2014)Background: Colistin (COL) has become the backbone of the treatment of infections due to extensively drug-resistant (XDR) Gram-negative bacteria. The most common restriction to its use is acute kidney injury (AKI). Methods: ... -
Comparison of colistin-carbapenem, colistin-sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter baumannii bloodstream infections
Batirel, Ayşe; Balkan, İlker İnanç; Karabay, Oğuz; Ağalar, Canan; Akalın, Şerife; Alıcı, Özlem; Alp, Emine; Altay, Fatma Aybala; Altın, Nilgün; Arslan, Ferhat; Aslan, Turan; Bekiroğlu, Nuray; Cesur, Salim; Çelik, Aygül Dogan; Doğan, Mustafa; Durdu, Bülent; Duygu, Fazilet; Engin, Aynur; Engin, Derya Öztürk; Gönen, İbak; Güçlü, Ertuğrul; Güven, Tümer; Hatipoğlu, Çiğdem Ataman; Hoşoğlu, Salih; Karahocagil, Mustafa Kasım; Ulu Kılıç, Aysegül; Örmen, Bahar; Özdemir, Davut; Özer, Serdar; Öztoprak, Nefise; Sezak, Nurbanu; Turhan, Vedat; Türker, Nesrin; Yılmaz, Hava (Springer, 2014)The purpose of this investigation was to compare the efficacy of colistin-based therapies in extremely drug-resistant Acinetobacter spp. bloodstream infections (XDR-ABSI). A retrospective study was conducted in 27 tertiary-care ... -
Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?
Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Özbek, Hanefi; Kaya, Yasin Emre; Akyuva, Yener; Kaplan, Necati; Doğan, Mustafa; Gümüştaş, Seyit Ali; Ateş, Özkan; Erdem, İlknur (Inonu University School of Medicine, 2018)Aim: In this study, it was firstly aimed to investigate the effect of Daptomycin (DAP) on the proliferation in Vancomycin (VCM)-administered primary chondrocyte cultures and non-drug-administered primary chondrocyte cultures. ... -
Efficacy of colistin and non-colistin monotherapies in multi-drug resistant acinetobacter baumannii bacteremia/sepsis
Karabay, Oğuz; Batırel, Ayşe; Balkan, İlker İnanç; Ağalar, Canan; Akalın, Şerife; Alıcı, Özlem; Alp, Emine; Aybala Alta, Fatma; Altın, Nilgün; Arslan, Ferhat; Aslan, Turan; Bekiroğlu, Nural; Cesur, Salim; Doğan Çelik, Aygül; Doğan, Mustafa; Durdu, Bülent; Duygu, Fazilet; Engin, Aynur; Öztürk Engin, Derya; Gönen, İbak; Güçlü, Ertuğrul; Güven, Tümer; Ataman Hatipoğlu, Çiğdem; Hoşoğlu, Salih; Karahocagil, Mustafa; Ulu Kılıç, Ayşegül; Örmen, Bahar; Özdemir, Davut; Özer, Serdal; Öztoprak, Nefise; Sezak, Nurbanu; Turhan, Vedat; Türker, Nesrin; Yılmaz, Hava (Acta Medica Mediterranea, 2014)Objective: This retrospective study aimed to investigate the efficacies of colistin and non-colistin monotherapies in multi-drug resistant Acinetobacter baumannii bacteremia (MDR-AB). Materials and methods: Cases with ... -
Evaluation of antibiotic alternatives used in orthopedic departments of 2 hospitals according to rational use of antibiotics
İşyar, Mehmet; Doğan, Mustafa; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Bilir, Bülent; Güler, Olcay; Saraçoğlu Varol, Gamze; Mahiroğulları, Mahir (Kare Yayıncılık ve İletişim Hizmetleri, 2016)Background: The present study is an analysis of appropriateness of antibiotics use for patients in whom infectious agent was detected. Data from patients in orthopedics and traumatology department of 2 hospitals in the ... -
Evaluation of empirical antibiotic treatment in culture negative pyogenic vertebral osteomyelitis
Doğan, Mustafa; Şimşek, Abdullah Talha; Yılmaz, İbrahim; Karaarslan, Numan (Turkish Neurosurgical Society, 2019)AIM: To investigate the efficacy of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis (PVO) cases. MATERIAL and METHODS: The records of patients with culture-negative PVO who were treated ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in spondylodiscitis
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalıskan, Tezcan; Doğan, Mustafa; Bilir, Bülent; Ateş, Özkan (2018)Aim: Spondylodiscitis, if not diagnosed on time, can cause morbidity or mortality at high rates. This study was carried out with the aim of testing the hypothesis that “neutrophil-to-lymphocyte ratio can be used” especially ... -
A study on side effects of antibiotics used in the treatment of patients with head trauma and legal responsibility of clinicians in terms of the right to health
Karaarslan, Abdulkadir; Şimşek, Abdullah Talha; Doğan, Mustafa; Potoğlu, Bilgehan; Yılmaz, İbrahim; Karaarslan, Numan (2019)Aim: Patients with head trauma are routinely, and commonly treated with prophylactic antibiotics, which may also be used for the treatment of infection that may be developed during hospital stay. The relevant antibiotic ...
