Browsing by Author "Demirel, Erhan"
Now showing items 1-5 of 5
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Bioconjugated beta-cyclodextrin-perfluorohexane nanocone clusters as functional nanoparticles for nanoparticle-mediated histotripsy
Toydemir, Cemran; Hall, Sarah; Demirel, Erhan; Elmacı, Dilşah Nur; Göl, Deniz; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin (American Chemical Society, 2022)Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs). NCCs can be obtained by simply mixing ... -
Development of acoustically active nanocones using the host-guest interaction as a new histotripsy agent
Rehman, Tanzeel Ur; Khirallah, Jennifer; Demirel, Erhan; Howell, Justin; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin (American Chemical Society, 2019)Histotripsy is a noninvasive and nonthermal ultrasound ablation technique, which mechanically ablates the tissues using very short, focused, high-pressured ultrasound pulses to generate dense cavitating bubble cloud. ... -
Effective PEGylation method to improve biocompatibility of graphene derivatives
Demirel, Erhan; Karaca, Ezgi; Yüksel Durmaz, Yasemin (Elsevier, 2020)The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ... -
Nanoparticle-mediated histotripsy (NMH) using perfluorohexane 'nanocones'
Khirallah, Jennifer; Schmieley, Rebecca; Demirel, Erhan; Ur Rehman, Tanzeel; Howell, Justin; Yüksel Durmaz, Yasemin; Vlaisavljevich, Eli (Institute of Physics Publishing, 2019)Nanoparticle-mediated histotripsy (NMH) is an ultrasound treatment strategy that combines acoustically sensitive nanoparticles with histotripsy. Previous NMH studies using perfluorocarbon (PFC) nanodroplets (ND's), ∼200 ... -
PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery
Demirel, Erhan; Yüksel Durmaz, Yasemin (Elsevier Ltd, 2023)Combination therapies involving anticancer drugs and gene therapy agents have become a potential treatment for different cancer types reducing the side effects of anticancer drugs while enhancing their effectiveness. Here, ...
