Browsing by Author "Demirci, Fatih"
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ACE2 and LOX enzyme inhibitions of different lavender essential oils and major components linalool and camphor
Biltekin, Sevde Nur; Karadağ, Ayşe Esra; Demirci, Betül; Demirci, Fatih (American Chemical Society, 2022)In this present study, Lavandula angustifolia, Lavandula stoechas, and Lavandula x heterophylla essential oils and their main compounds linalool and camphor were evaluated in vitro for lipoxygenase enzyme (LOX) and for ... -
Anti-inflammatory, analgesic and in vivo-in vitro wound healing potential of the Phlomis rigida Labill. extract
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Kültür, Şükran; Demirci, Betül; Demirci, Fatih (Elsevier Ireland Ltd, 2021)Ethnopharmacological relevance: The preparations of Phlomis aerial parts are used traditionally in Anatolia for wound healing and in inflammatory disorders. Methods: For the identification of the active fraction, the air ... -
Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
Karadağ, Ayşe Esra; Demirci, Betül; Kültür, Şükran; Demirci, Fatih; Başer, K. Hüsnü Can (Taylor and Francis Inc., 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Bioautography for evaluation of several Lavandula L. and origanum species antimicrobial and antioxidant activity
Karavuş, Şule Nur; Çaşkurlu, Ayşegül; Karadağ, Ayşe Esra; Demirci, Fatih (Istanbul Medipol University, 2023)In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal ... -
Chemical characterization and multidirectional biological effects of different solvent extracts of arum elongatum: in vitro and in silico approaches
Fawzi Mahomoodally, Mohamad; Zengin, Gökhan; Roumita, Seebaluck-Sandoram; Caprioli, Giovanni; Mustafa, Ahmed M.; Piatti, Diletta; Yıldıztugay, Evren; Ak, Güneş; Karadağ, Ayşe Esra; Khalid, Asaad; Abdalla, Ashraf N.; İbrahim Uba, Abdullahi; Demirci, Fatih (Wiley-VCH Verlag, 2023)Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual ... -
Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils
Karadağ, Ayşe Esra; Demirci, Betül; Çeçen, Ömer; Tosun, Fatma; Demirci, Fatih (Consejo Superior de Investigaciones Científicas (CSIC), 2021)The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One ... -
Evaluation of in vitro anti-cancer effects of Styphnolobium japonicum root extract in human colon (HT-9), brain (U-87), and prostate (PC-3) cancer cell lines
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Öztunç, Nurşah; Tosyalı, İbrahim Serkut; Demirci, Fatih (İstanbul University, 2020)Background and Aims: Styphnolobium japonicum (L.) Schott. (Sophora japonica) is a medicinal plant applied for various diseases, in the traditional medicine field. The evaluation of methanol extract of S. japonicum root ... -
Hemostatic activity of cistus creticus extract in wistar albino rats
Karadağ, Ayşe Esra; Çaşkurlu, Ayşegül; Okur, Mehmet Evren; Güzelmeriç, Etil; Üstündağ Okur, Neslihan; Tosun, Fatma; Yeşilada, Erdem; Demirci, Fatih (Springer Nature, 2020)Aerial part preparations of Cistus creticus L., Cistaceae, are traditionally used in Anatolia as a hemostatic agent. The air-dried aerial parts were extracted with methanol. Gels were prepared, followed by the hemostatic ... -
In vitro ACE2 and 5-LOX enzyme inhibition by menthol and three different mint essential oils
Demirci, Fatih; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül (SAGE Publications Inc., 2021)Mentha arvensis L., M. citrata L., and M. spicata L. (family Lamiaceae) essential oils, and their characteristic constituent, menthol, were evaluated in vitro for angiotensin converting enzyme 2 (ACE2) and 5-lipoxygenase ... -
In vitro ACE2 and 5-LOX inhibition of rosmarinus officinalis l. essential oil and its major component 1,8-cineole
Demirci, Fatih; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül (ACG Publications, 2022)In this present study, Rosmarinus officinalis L. essential oil, and its major component 1,8-cineole was evaluated in vitro for angiotensin converting enzyme 2 (ACE2), as well as for 5-lipoxygenase (5-LOX) enzyme inhibitory ... -
In vitro ACE2 enzyme inhibitory activity evaluation of different salvia essential oils
Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Demirci, Betül; Demirci, Fatih (Istanbul Medipol University, 2022)In this present study, commertially available Salvia triloba L., S.officinalis L., and S. sclarea L. essential oils were evaluated for their in vitro angiotensin converting enzyme 2 (ACE2) inhibitory activity. The Salvia ... -
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of eucalyptus essential oils, 1,8-cineole, and citronellal
Ak Sakallı, Ezgi; Teralı, Kerem; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Koşar, Müberra; Demirci, Betül; Başer, Kemal Hüsnü Can; Demirci, Fatih (SAGE Publications Inc., 2022)Eucalyptus essential oils are well-known and used especially in upper respiratory tract pathologies or diseases as herbal drug preparations. In the present study, the in vitro angiotensin-converting enzyme 2 (ACE2) and ... -
In vitro antibacterial, antioxidant, anti-inflammatory and analgesic evaluation of Rosmarinus officinalis L. flower extract fractions
Karadağ, Ayşe Esra; Demirci, Betül; Çaşkurlu, Ayşegül; Demirci, Fatih; Okur, Mehmet Evren; Orak, Deborah; Sipahi, Hande; Başer, Kemal Hüznü Can (Elsevier, 2019)Rosmarinus officinalis L. (rosemary) is a common culinary spice and herbal drug, which is used for centuries all over the world. In this present study, apolar to polar fractions of R. officinalis flowers were evaluated for ... -
In Vitro Antiviral Evaluations of Coldmix®: An Essential Oil Blend against SARS-CoV-2
Başer, Kemal Hüsnü Can; Karadağ, Ayşe Esra; Biltekin, Sevde Nur; Ertürk, Murat; Demirci, Fatih (NLM (Medline), 2023)Coldmix® is a commercially available Eucalyptus aetheroleum and, Abies aetheroleum blend for medicinal applications. In this present study, the in vitro antiviral potential of Coldmix®, and its major constituents 1,8-cineole ... -
In vitro cytotoxicity evaluation of Marrubium vulgare L. methanol extract
Okur, Mehmet Evren; Karakaş, Nihal; Karadağ, Ayşe Esra; Yılmaz, Rabia; Demirci, Fatih (Marmara University, 2019)Marrubium vulgare L. (Lamiaceae) is a herbal drug used for centuries for many diseases. In this present study the plant material was acquired from commercial sources in pharma grade (PhEur 8.0) quality. The methanol extract ... -
In vivo wound healing and in vitro anti-inflammatory activity evaluation of phlomis russeliana extract gel formulations
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Üstündağ Okur, Neslihan; Özhan, Yağmur; Sipahi, Hande; Ayla, Şule; Daylan, Benay; Demirci, Betül; Demirci, Fatih (MDPI, 2020)The air-dried aerial parts of Phlomis russeliana (Sims) Lag. Ex Benth. was extracted by methanol and fractionated by n-hexane, dichloromethane, and ethyl acetate, respectively. The wound healing properties of P. russeliana ... -
Matrin ve oksimatrinin mikrobiyal transformasyonu ve metabolitlerinin in vitro biyolojik aktivitelerinin incelenmesi
Karadağ, Ayşe Esra; Demirci, Fatih (Mersin Üniversitesi, 2020)Amaç: Matrin ve oksimatrin bileşiklerinin mikrobiyal transformasyon yolu ile metabolitlerin karşılaştırmalı olarak biyolojik aktivitelerinin incelenmesi hedeflenmiştir. Yöntem:30 farklı mikroorganizmanın sıvı besiyerinde ... -
Phytochemical and in vitro pharmacological evaluation of Phlomis Pungens
Okur, Mehmet Evren; Karadağ, Ayşe Esra; Reis, Rengin; Sipahi, Hande; Arslan, Rana; Demirci, Betül; Demirci, Fatih (Ankara University, 2022)Objective: This study aimed to investigate the in vitro wound healing, anti-inflammatory, antimicrobial and antioxidant activity of Phlomis pungens Willd. extract derived from the aerial parts. Material and Method: The ... -
Rosmarinus officinalis L. essential oil encapsulated in new microemulsion formulations for enhanced antimicrobial activity
Karadağ, Ayşe Esra; Üstündağ Okur, Neslihan; Demirci, Betül; Demirci, Fatih (Wiley, 2022)In this present study, Rosmarinus officinalis essential oil and its new microemulsions (MEs) were evaluated both for the in vitro antibacterial and antifungal activity. The essential oil composition was verified initially ... -
Synthesis, antimicrobial and antioxidant activities of pyridyl substituted thiazolyl triazole derivatives
Tay, Naime Funda; Duran, Murat; Kayagil, İsmail; Yurttaş, Leyla; Göger, Gamze; Göğer, Fatih; Demirci, Fatih; Demirayak, Şeref (Universidade de São Paulo, 2022)In this present study, 63 different 5-[4-methyl-2-(pyridin-3/4-yl)thiazole-5-yl]-4-substituted-3-substituted benzylthio-4H-1,2,4-triazole derivatives were synthesized, and evaluated for their in vitro antimicrobial activity ...
