Browsing by Author "Aydın, Mehmet Şerif"
Now showing items 1-17 of 17
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Active shrinkage protects neurons following axonal transection
Aydın, Mehmet Şerif; Bay, Sadık; Yiğit, Esra Nur; Özgül, Cemil; Kaval Oğuz, Elif; Yenidünya Konuk, Elçin; Ayşit, Neşe; Cengiz, Nureddin; Erdoğan, Ender; Him, Aydın; Koçak, Mehmet; Eroğlu, Emrah; Öztürk, Gürkan (Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
Kazcı, Yusuf Enes; Şahoğlu Göktaş, Sevilay; Aydın, Mehmet Şerif; Karadoğan, Behnaz; Nebol, Aylin; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
Söylemez, Esra; Özçağlı, Eren; Korkmaz, Serol; Tok, Olgu Enis; Aydın, Mehmet Şerif; Omurtag, Gülden Zehra (SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Different concentrations of mesna application have an effect on the internal ear?
Doğan, Remzi; Eren, Sabri Baki; Gedik, Özge; Yenigün, Alper; Aydın, Mehmet Şerif; Eser, Büşranur; Özturan, Orhan (Elsevier Ireland Ltd, 2018)Objective: The use of Mesna as a chemical dissector in higher concentrations may reduce the length of time of operation by providing more effective dissection as well as being used in otologic pathologies such as ... -
Effect of grape seed extract on bone formation in the expanded inter-premaxillary suture
Aksakallı, Sertaç; Ezirganlı, Şeref; Birlik, Muhammet; Kazancıoğlu, Hakkı Oğuz; Aydın, Mehmet Şerif (Galenos Yayıncılık, 2020)Objective: Widening the inter-maxillary suture is a preferred procedure in orthodontics. However, relapse can occur in some patients after maxillary expansion therapy. This study aimed to increase bone formation in the ... -
Effects of a thermosensitive in situ gel containing mometasone furoate on a rat allergic rhinitis model
Altuntaş, Ebru; Yener, Gülgün; Doğan, Remzi; Aksoy, Fadlullah; Aydın, Mehmet Şerif; Karataş, Ersin (Sage Publications Inc, 2018)Background: Mometasone furoate, one of the second generation intranasal corticosteroids, is currently used in suspension form due to its poor solubility. However, this is not favorable for nasal application because of the ... -
The effects of human amniotic membrane on silicone related capsule formation in rats
Akyürek, Mustafa; Orhan, Erkan; Aydın, Mehmet Şerif; Uysal, Ömer; Karşıdağ, Semra (Taylor and Francis Ltd., 2020)Silicone breast implants are commonly used materials in plastic surgery for breast augmentation and reconstruction and the most severe complication of silicone implants are capsule contraction which occurs in 40% of patients. ... -
The effects of transcranial focused ultrasound stimulation of nucleus accumbens on neuronal gene expression and brain tissue in high alcohol-preferring rats
Deveci, Erdem; Akbaş, Fahri; Ergün, Arif Şanlı; Kurtulmuş, Ayşe; Koçak, Ali Barlas; Boyraz, Rabia Kevser; Tok, Olgu Enis; Aydın, Mehmet Şerif; Kılıç, Özge; Bozkurt, Ayhan; Uysal, Ömer; Eşrefoğlu, Mukaddes (Springer, 2023)We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histological effects on brain tissue. We also aimed at determining the miRNA-mRNA relationship and ... -
Evaluation of ototoxicity of intratympanic administration of Methotrexate in rats
Eren, Sabri Baki; Doğan, Remzi; Yenigün, Alper; Veyseller, Bayram; Tuğrul, Selahattin; Özturan, Orhan; Aydın, Mehmet Şerif (Elsevier Ireland Ltd., 2017)Objective: Methotrexate is a dihydrofolate reductase enzyme inhibitor with very high selectivity, and it is an antiproliferative folic acid antagonist used for the treatment of autoimmune diseases. In this study, our ... -
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
Akgül Çağlar, Tuba; Durdu, Zeynep Begüm; Turhan, M. U.; Günal, Mehmet Yalçın; Aydın, Mehmet Şerif; Öztürk, Gürkan; Çağavi, Esra (Elsevier, 2021)The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ... -
High-resolution mapping of sensory fibers at the healthy and post-myocardial infarct whole transgenic hearts
Göktaş Şahoğlu, Sevilay; Kazcı, Yusuf Enes; Karadoğan, Behnaz; Aydın, Mehmet Şerif; Nebol, Aylin; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Wiley, 2023)The sensory nervous system is critical to maintain cardiac function. As opposed to efferent innervation, less is known about cardiac afferents. For this, we mapped the VGLUT2-expressing cardiac afferent fibers of spinal ... -
Histopathological evaluation of Ankaferd blood stopper use in the rabbit septoplasty model
Orhan, İsrafil; Doǧan, Remzi; Soylu, Erkan; Aksoy, Fadlullah; Veyseller, Bayram; Özturan, Orhan; Eşrefoǧlu, Mukaddes; Aydın, Mehmet Şerif (Elsevier Ireland, 2015)Objective: The purpose of this study was to assess the use of Ankaferd blood stopper (ABS), an organic hemostatic agent of plant origin, in septoplasty operations, and to determine its effect on nasal septal tissues in the ... -
Impaired follicular development and ovulation in PCOS mouse model can rescued by rapamycin treatment
Yaba, Aylin; Aydın, Mehmet Şerif; Ağuş, Sami; Günalan, Elif; Yıldırım, Ecem Nur; Yılmaz, Bayram (Oxford University Press, 2018)Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder affecting 5-10% of women in reproductive age that is characterized by hyperandrogenism, oligo- or anovulation and infertility. However the ... -
Lithium promotes long-term neurological recovery after spinal cord injury in mice by enhancing neuronal survival, gray and white matter remodeling, and long-distance axonal regeneration
Balçıkanlı, Zeynep; Çulha, İrem; Dilsiz, Pelin; Aydın, Mehmet Şerif; Ateş, Nilay; Beker, Mustafa Çağlar; Baltacı, Saltuk Buğra; Koç, Halil İbrahim; Yiğitbaşı, Ahmet; Gündoğar, Mustafa; Doeppner, Thorsten Roland; Hermann, Dirk M. (Frontiers Media S.A., 2022)Spinal cord injury (SCI) induces neurological deficits associated with long-term functional impairments. Since the current treatments remain ineffective, novel therapeutic options are needed. Besides its effect on bipolar ... -
Therapeutic effects of metformin for noise induced hearing loss
Gedik, Özge; Doǧan, Remzi; Babademez, Mehmet Ali; Karataş, Ersin; Aydın, Mehmet Şerif; Koçyiǧit, Abdurrahim; Eşrefoǧlu, Mukaddes; Özturan, Orhan (W.B. Saunders, 2020)Objective: This study aimed to investigate the healing effect of metformin on noise induced hearing loss (NIHL) by measuring audiological, biochemical and histological parameters.Materials and methods: 32 rats were divided ... -
Transfer and integration of breast milk stem cells to the brain of suckling pups
Aydın, Mehmet Şerif; Yiğit, Esra Nur; Vatandaşlar, Emre; Erdoğan, Ender; Öztürk, Gürkan (Nature Publishing Group, 2018)Beside its unique nutritional content breast milk also contains live cells from the mother. Fate of these cells in the offspring has not been adequately described. In this study, we aimed to detect and identify maternal ...
