Browsing by Author "Aydın, Ömer"
Now showing items 1-6 of 6
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Effects of droplet composition on nanodroplet-mediated histotripsy
Vlaisavljevich, Eli; Aydın, Ömer; Durmaz Yüksel, Yasemin; Lin, Kuang-Wei; Fowlkes, Brian; Xu, Zhen; ElSayed, Mohamed E. H. (Elsevier Science Inc, 2016)Nanodroplet-mediated histotripsy (NMH) is a targeted ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. In two previous studies, polymer-encapsulated perfluoropentane ... -
Effects of ultrasound frequency on nanodroplet-mediated histotripsy
Vlaisavljevich, Eli; Aydın, Ömer; Yüksel Durmaz, Yasemin; Lin, Kuangwei; Fowlkes, Brian; Elsayed, Mohamed; Xu, Zhen (Elsevier Science, 2015)Nanodroplet-mediated histotripsy (NMH) is a targeted ultrasound ablation technique combining histotripsy with nanodroplets that can be selectively delivered to tumor cells for targeted tumor ablation. In a previous study, ... -
Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
Aydın, Ömer; Youssef, İbrahim; Durmaz Yüksel, Yasemin; Tiruchinapally, Gopinath; ElSayed, Mohamed E. H. (Amer Chemical Soc, 2016)We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ... -
Noninvasive ablation of prostate cancer spheroids using acoustically-activated nanodroplets
Aydın, Ömer; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin; Xu, Zhen; ElSayed, Mohamed E. H. (Amer Chemical Soc, 2016)We have developed acoustically activated nanodroplets (NDs) using an amphiphilic triblock copolymer, which self-assembles and encapsulates different perfluorocarbons including perfluoropentane (PFP) and perfluorohexane ... -
The role of positive and negative pressure on cavitation nucleation in nanodroplet-mediated histotripsy
Vlaisavljevich, Eli; Aydın, Ömer; Lin, Kuang-Wei; Durmaz Yüksel, Yasemin; Fowlkes, Brian; ElSayed, Mohamed; Xu, Zhen (Iop Publishing Ltd, 2016)Nanodroplet-mediated histotripsy (NMH) is an ultrasound ablation technique combining histotripsy with acoustically sensitive perfluorocarbon (PFC) nanodroplets that can be selectively delivered to tumor cells for targeted ... -
Selective binding of pVTK peptide-and bisphosphonate-functionalized micelles to prostate cancer cells, osteoblasts, and osteoclasts
Aydın, Ömer; Tiruchinapally, Gopinath; Youssef, Ibrahim; Ramaraju, Harsha; Yüksel Durmaz, Yasemin; Kozloff, Kenneth M.; Kohn, David H.; Elsayed, Mohamed E. H. (Andover House, Inc., 2022)This report describes the development of functionalized polymeric micelles encapsulating a chemotherapeutic agent. The results indicate the ability to achieve selective uptake into different cell populations in metastatic ...
