Browsing by Author "Aycan, Zehra"
Now showing items 1-3 of 3
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Comprehensive screening of eight known causative genes in congenital hypothyroidism with gland-in-situ
Nicholas, Adeline K.; Serra, Eva Goncalves; Cangül, Hakan; Al-Yaarubi, Saif; Ullah, Irfan; Schoenmakers, Erik; Deeb, Asma; Habeb, Abdelhadi M.; Almaghamsi, Mohammad; Peters, Catherine; Nathwani, Nisha; Aycan, Zehra; Sağlam, Halil; Bober, Ece; Dattani, Mehul; Shenoy, Savitha; Murray, Philip G.; Babiker, Amir; Willemsen, Ruben; Thankamony, Ajay; Lyons, Greta; Irwin, Rachael; Padidela, Raja; Tharian, Kavitha; Davies, Justin Huw; Puthi, Vijith; Park, Soo-Mi; Massoud, Ahmed F.; Gregory, John W.; Albanese, Assunta; Pease-Gevers, Evelien; Martin, Howard; Brugger, Kim; Maher, Eamonn R.; Chatterjee, V. Krishna K.; Anderson, Carl A.; Schoenmakers, Nadia (Endocrine Society, 2016)Context: Lower TSH screening cutoffs have doubled the ascertainment of congenital hypothyroidism (CH), particularly cases with a eutopically located gland-in-situ (GIS). Although mutations in known dyshormonogenesis genes ... -
Digenic DUOX1 and DUOX2 mutations in cases with congenital hypothyroidism
Aycan, Zehra; Cangül, Hakan; Muzza, Marina; Bas, Veysel N.; Fugazzola, Laura; Chatterjee, V. Krishna; Persani, Luca; Schoenmakers, Nadia (Oxford University Press Inc, 2017)Context: The DUOX2 enzyme generates hydrogen peroxide (H2O2), a crucial electron acceptor for the thyroid peroxidase-catalyzed iodination and coupling reactions mediating thyroid hormone biosynthesis. DUOX2 mutations result ... -
Response to growth hormone treatment in very young patients with growth hormone deficiencies and mini-puberty
Çetinkaya, Semra; Poyrazoğlu, Şükran; Baş, Firdevs; Ercan, Oya; Yıldız, Metin; Adal, Erdal; Bereket, Abdullah; Abalı, Saygın; Aycan, Zehra; Erdeve, Senay Savaş; Berberoğlu, Merih; Şıklar, Zeynep; Tayfun, Meltem; Darcan, Şükran; Mengen, Eda; Bircan, İffet; Jones, Filiz Mine Çizmecioğlu; Şimşek, Enver; Papatya, Esra Deniz; Özbek, Mehmet Nuri; Bolu, Semih; Abacı, Ayhan; Büyükinan, Muammer; Darendeliler, Feyza (Walter de Gruyter Gmbh, 2018)Background: The aim of the study was to assess the response to growth hormone (GH) treatment in very young patients with GH deficiency (GHD) through a national, multi-center study. Possible factors affecting growth response ...
